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A common genetic factor explains the covariation among ADHD ODD and CD symptoms in 9-10 year old boys and girls
Department of Psychology, University of Southern California, Los Angeles, United States. (CAPS)ORCID iD: 0000-0001-8768-6954
Department of Psychology, University of Southern California, Los Angeles, United States.
Departments of Criminology, Psychiatry, and Psychology, University of Pennsylvania, Los Angeles, United States .
Department of Psychology, University of Southern California, Los Angeles, United States.
2009 (English)In: Journal of Abnormal Child Psychology, ISSN 0091-0627, E-ISSN 1573-2835, Vol. 37, no 2, 153-167 p.Article in journal (Refereed) Published
Abstract [en]

Previous studies examining the covariation among Attention Deficit Hyperactivity Disorder (ADHD), Oppositional Defiant Disorder (ODD) and Conduct Disorder (CD) have yielded inconsistent results. Some studies have concluded that the covariation among these symptoms is due to common genetic influences, whereas others have found a common environmental overlap. The present study investigated the genetic and environmental correlations among these three childhood disorders, based on a sample of 1,219 twins, age 9-10 years. A latent externalizing behavior factor was found to explain the covariance among ADHD, ODD and CD symptoms. Genetic influences explained more than half of the variance in this externalizing factor in both boys and girls. There were also unique genetic and environmental influences in each set of symptoms, suggesting some etiological independence of the three disorders. Our findings have implications for molecular genetic studies trying to identify susceptibility genes for these disorders.

Place, publisher, year, edition, pages
2009. Vol. 37, no 2, 153-167 p.
Keyword [en]
ADHD; CD; Covariation; Genetic influences; ODD; Twins
National Category
Psychology
Research subject
Psychology
Identifiers
URN: urn:nbn:se:oru:diva-41059DOI: 10.1007/s10802-008-9278-9ISI: 000262986600002PubMedID: 19015975Scopus ID: 2-s2.0-59449084667OAI: oai:DiVA.org:oru-41059DiVA: diva2:782607
Available from: 2015-01-21 Created: 2015-01-12 Last updated: 2015-03-31Bibliographically approved

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