oru.sePublikationer
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Smoking cessation and the risk of cataract: a prospective cohort study of cataract extraction among men
Örebro University, School of Health and Medical Sciences, Örebro University, Sweden. Orebro University Hospital. Department of Ophthalmology, Örebro University Hospital, Örebro; Institute of Environmental Medicine, Karolinska Institutet, Stockholm.
Institute of Environmental Medicine, Karolinska Institutet, Stockholm.
Institute of Environmental Medicine, Karolinska Institutet, Stockholm.
2014 (English)In: JAMA ophthalmology, ISSN 2168-6165, E-ISSN 2168-6173, Vol. 132, no 3, 253-7 p.Article in journal (Refereed) Published
Abstract [en]

Importance: Smoking is a risk factor for cataract development, but the effect of smoking cessation on the risk of cataract is uncertain.

Objective: To examine the association between smoking cessation and the risk of cataract extraction.

Design, setting, and participants: A total of 44,371 men, participating in the Cohort of Swedish Men, aged 45 to 79 years, who in 1997 completed a self-administered questionnaire on smoking habits and lifestyle factors. The men were followed up from January 1, 1998, through December 31, 2009. The cohort was matched with the Swedish National Day-Surgery Register and local registers of cataract extraction in the study area.

Main outcomes and measures: Incident cases of age-related cataract extraction.

Results: During 12 years of follow-up, we identified 5713 incident cases of age-related cataract extraction. Smoking intensity and cumulative dose of smoking were associated with an increased risk of cataract extraction (P for trend <.001). Current smokers of more than 15 cigarettes per day had a 42% increased risk of cataract extraction (rate ratio, 1.42; 95% CI, 1.28-1.58) compared with never smokers after adjustment for age and other potential risk factors. Smoking cessation significantly decreased the risk for cataract extraction with time (P for trend <.001). After more than 20 years since stopping smoking, men with a mean smoking intensity of more than 15 cigarettes per day had a 21% increased risk of cataract extraction (rate ratio, 1.21; 95% CI, 1.06-1.39) compared with never smokers. Among men who smoked 15 cigarettes or less per day, the effect of smoking cessation was observed earlier, but more than 2 decades after smoking cessation, the risk of cataract extraction did not decrease to the level of never smokers (rate ratio, 1.13; 95% CI, 1.04-1.24).

Conclusion and relevance: Smoking cessation seems to decrease the risk of cataract extraction with time, although the risk persists for decades. The higher the intensity of smoking, the longer it takes for the increased risk to decline. These findings emphasize the importance of early smoking cessation and preferably the avoidance of smoking.

Place, publisher, year, edition, pages
Chicago, USA: American Medical Association , 2014. Vol. 132, no 3, 253-7 p.
National Category
Ophthalmology
Identifiers
URN: urn:nbn:se:oru:diva-44394DOI: 10.1001/jamaophthalmol.2013.6669ISI: 000332774000003PubMedID: 24385206Scopus ID: 2-s2.0-84896257926OAI: oai:DiVA.org:oru-44394DiVA: diva2:806842
Note

Funding Agencies:

Swedish Council for Working Life and Social Research, Stockholm, Sweden

Örebro County Council, Örebro, Sweden

Available from: 2015-04-21 Created: 2015-04-21 Last updated: 2017-03-15Bibliographically approved

Open Access in DiVA

No full text

Other links

Publisher's full textPubMedScopus

Search in DiVA

By author/editor
Lindblad, Birgitta Ejdervik
By organisation
School of Health and Medical Sciences, Örebro University, SwedenOrebro University Hospital
In the same journal
JAMA ophthalmology
Ophthalmology

Search outside of DiVA

GoogleGoogle Scholar

Altmetric score

Total: 57 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf