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Programming infant gut microbiota: influence of dietary and environmental factors
Alimentary Pharmabiotic Centre (APC), University College Cork, Cork, Ireland; Moorepark Teagasc Food Research Centre, Fermoy, Ireland; Department of Microbiology, University College Cork, Cork, Ireland.
Alimentary Pharmabiotic Centre (APC), Cork, Ireland. (Nutrition-Gut-Brain Interactions Research Centre)
Alimentary Pharmabiotic Centre (APC), Cork, Ireland; Moorepark Teagasc Food Research Centre, Fermoy, Ireland.
Alimentary Pharmabiotic Centre (APC), Cork, Ireland; Department of Microbiology, University College Cork, Cork, Ireland.
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2010 (English)In: Current Opinion in Biotechnology, ISSN 0958-1669, E-ISSN 1879-0429, Vol. 21, no 2, p. 149-156Article, review/survey (Refereed) Published
Abstract [en]

The neonatal period is crucial for intestinal colonisation, and the composition of this ecosystem in early life is influenced by such factors as mode of birth, environment, diet and antibiotics. The intestinal microbiota contributes to protection against pathogens, maturation of the immune system and metabolic welfare of the host, but under some circumstances can contribute to the pathogenesis of certain diseases. Because colonisation with non-pathogenic microbiota is important for infant health and may affect health in later life, it is important to understand how the composition of this microbial organ is established and by which dietary means (e.g. supplementation with prebiotics/probiotics/food ingredients) it can be programmed in order to achieve an ecosystem that is valuable for the host.

Place, publisher, year, edition, pages
Oxford, United Kingdom: Elsevier, 2010. Vol. 21, no 2, p. 149-156
National Category
Medical and Health Sciences Biochemistry and Molecular Biology
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URN: urn:nbn:se:oru:diva-46366DOI: 10.1016/j.copbio.2010.03.020ISI: 000278303100006PubMedID: 20434324Scopus ID: 2-s2.0-77952670363OAI: oai:DiVA.org:oru-46366DiVA, id: diva2:866254
Available from: 2015-11-02 Created: 2015-11-02 Last updated: 2018-09-07Bibliographically approved

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Wall, Rebecca

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