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Cancer Characteristics and Current Treatments of Patients with Renal Cell Carcinoma in Sweden
Department of Surgical and Perioperative Sciences, Urology and Andrology, Umeå University, Umeå, Sweden; Department of Molecular Medicine and Surgery, Section of Urology, Karolinska Institute, Stockholm, Sweden; Surgical Intervention Trials Unit, Nuffield Department of Surgical Sciences, University of Oxford, Oxford, United Kingdom.
Department of Oncology, Karolinska University Hospital, Solna, Stockholm, Sweden.
Örebro University, School of Medicine, Örebro University, Sweden. Dept Urol.
Department of Urology, Akademiska University Hospital, Uppsala, Sweden.
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2015 (English)In: BioMed Research International, ISSN 2314-6133, E-ISSN 2314-6141, 456040Article in journal (Refereed) Published
Abstract [en]

Methodology: Since the start in 2005 virtually all patients with newly diagnosed renal cell carcinoma (RCC) in Sweden are reported to the National Swedish Kidney Cancer Register (NSKCR). The register contains information on histopathology, nuclear grade, clinical stage, preoperative work-up, treatment, recurrence, and survival.

Results: A total of 8556 patients with newly diagnosed RCC were registered in the NSKCR from 2005 to 2013 resulting in a coverage of 99% as compared to the Swedish Cancer Registry. The mean tumor size at detection decreased from 70 mm in 2005 to 64 mm in 2010. The proportion of patients who were incidentally detected increased. The proportion of patients with tumor stage T1a who underwent partial nephrectomy increased from 22% in 2005 to 56% in 2012. Similarly, the proportion of laparoscopically performed radical nephrectomies increased from 6% in 2005 to 17% in 2010. During the five years of follow-up 20% of the patients had a recurrence.

Conclusion: Over the last decade there has been a trend of earlier detection and less advanced tumors at detection in patients with RCC. An increasing proportion of the patients undergo laparoscopic and nephron-sparing procedures.

Place, publisher, year, edition, pages
Hindawi Publishing Corporation, 2015. 456040
National Category
Microbiology in the medical area Cancer and Oncology
Research subject
Biomedicine; Microbiology
Identifiers
URN: urn:nbn:se:oru:diva-46509DOI: 10.1155/2015/456040ISI: 000363574700001PubMedID: 26539495Scopus ID: 2-s2.0-84945951071OAI: oai:DiVA.org:oru-46509DiVA: diva2:871997
Note

Funding Agencies:

Umeå University

Lions Cancer Research Foundation

Research Foundation at the Urology Department of Sahlgrenska University Hospital

Foundation of Anna-Lisa and Bror Björnsson

Stockholm Cancer Society

Capio S:t Görans Hospital

Available from: 2015-11-17 Created: 2015-11-16 Last updated: 2017-03-20Bibliographically approved

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