oru.sePublikationer
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Effects of antenatal lifestyle intervention on offspring obesity: a five year follow-up of a randomized controlled trial
Örebro University, School of Medical Sciences.
Örebro University, School of Health Sciences.
Örebro University, School of Medical Sciences.
(English)Manuscript (preprint) (Other academic)
National Category
Surgery
Research subject
Surgery
Identifiers
URN: urn:nbn:se:oru:diva-51911OAI: oai:DiVA.org:oru-51911DiVA: diva2:957095
Available from: 2016-09-02 Created: 2016-08-31 Last updated: 2017-10-17Bibliographically approved
In thesis
1. Gestational Weight Gain: Implications of an Antenatal Lifestyle Intervention
Open this publication in new window or tab >>Gestational Weight Gain: Implications of an Antenatal Lifestyle Intervention
2016 (English)Doctoral thesis, comprehensive summary (Other academic)
Abstract [en]

Background: Excessive gestational weight gain (GWG) is common in developed countries and is associated with an increased risk of maternal and offspring morbidity. Evidence regarding efficacy and safety of antenatal lifestyle intervention is limited in terms of both systematic reviews and original trials. This thesis is based on the need to further explore this research area. Objectives: To assess and grade current evidence and evaluate short and long-term effects of an antenatal lifestyle intervention on women and their offspring Materials: Controlled trials of intervention publishedbefore August 2009 were systematically searched and reviewed. A randomized controlled trial (RCT) including 445 healthy women aged >18 years with a body mass index (BMI) ≥19 and ≤16 weeks pregnant and their offspring was performed during 2007-2015 in Örebro Region, Sweden. Methods: The Grading of Recommendations, Assessment, Development and Evaluation (GRADE) system was used for review. Our RCT (called the VIGA trial) compared standard care with a composite intervention consisting of education, application of a personalized weight graph, prescription of exercise and more frequent monitoring of weight. Standardized measures of weight and height in offspring waere analysed based on World Health Organization (WHO) Child Growth Standards. Results: Quality of evidence across the studies published pre-August 2009 was concluded to be very low. Our intervention significantly reduced mean GWG (kg) but the proportion of women with excessive GWG, according to recommendations, was not significantly reduced. Short- term postpartum weight retention (PPWR) was significantly lower after the intervention but no significant difference remained 1 year after delivery. Offspring mean BMI z-scores or proportion of obesity did not differ between study groups at either birth or age 5. Conclusions: The antenatal lifestyle intervention reduced mean GWG and short-term PPWR but no long-term effects on maternal weight retention or offspring obesity were seen. Alternative modes and timing of intervention should be considered in future research. Reducing the prevalence of pre-conception obesity must still be considered the primary means to improve maternal and fetal outcome.

Place, publisher, year, edition, pages
Örebro: Örebro university, 2016. 61 p.
Series
Örebro Studies in Medicine, ISSN 1652-4063 ; 146
Keyword
gestational weight gain, maternal health, pregnancy, prevention of obesity, lifestyle intervention, childhood obesity
National Category
Surgery
Research subject
Surgery
Identifiers
urn:nbn:se:oru:diva-51439 (URN)978-91-7529-148-2 (ISBN)
Public defence
2016-09-30, Örebro universitet, Campus USÖ, hörsal C1, Södra Grev Rosengatan 32, Örebro, 09:00 (Swedish)
Opponent
Supervisors
Available from: 2016-07-25 Created: 2016-07-25 Last updated: 2017-10-17Bibliographically approved

Open Access in DiVA

No full text

Search in DiVA

By author/editor
Rönnberg, Ann-KristinHanson, UlfNilsson, Kerstin
By organisation
School of Medical SciencesSchool of Health Sciences
Surgery

Search outside of DiVA

GoogleGoogle Scholar

Total: 92 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf