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Pre- and postoperative atrial fibrillation in CABG patients have similar prognostic impact
Örebro University, School of Health Sciences. Departments of Cardiology and Cardiothoracic Surgery, Örebro University Hospital, Örebro, Sweden.
Karolinska Institute, Department of Clinical Sciences at South Hospital and Arrhythmia Center, Stockholm, Sweden.
Örebro University, School of Medical Sciences. Departments of Cardiology and Cardiothoracic Surgery, Örebro University Hospital, Örebro, Sweden.ORCID iD: 0000-0002-6913-0669
2016 (English)In: Scandinavian Cardiovascular Journal, ISSN 1401-7431, E-ISSN 1651-2006Article in journal (Refereed) Epub ahead of print
Abstract [en]

Objectives: To study pre- and postoperative atrial fibrillation and its long-term effects in a cohort of aortocoronary bypass surgery patients.

Design: Altogether 615 patients undergoing aortocoronary bypass graft surgery in 1999-2000 were studied. Forty-four (7%) had preoperative atrial fibrillation. Postoperative atrial fibrillation occurred in 165/615 patients (27%) while 406/615 patients (66%) had no atrial fibrillation. After a median follow-up of 15 years, symptoms and medication in survivors were recorded, and cause of death in the deceased was obtained.

Results: Death due to cerebral ischaemia was most common in the pre- and postoperative atrial fibrillation groups (7% and 5%, respectively, v. 2% among those without atrial fibrillation, p = 0.038), as were death due to heart failure (18% and 14%, v. 7%, p = 0.007) and sudden death (9% and 5%, v. 2%, p = 0.029). The presence of pre- or postoperative atrial fibrillation was an independent risk factor for late mortality (hazard ratios 1.47 (1.02-2.12) and 1.28 (1.01-1.63), respectively).

Conclusions: Patients with pre- or postoperative atrial fibrillation undergoing aortocoronary bypass surgery have increased long-term mortality and risk of cerebral ischemic and cardiovascular death compared with patients in sinus rhythm.

Place, publisher, year, edition, pages
Oxfordshire, United Kingdom: Taylor & Francis, 2016.
Keyword [en]
Atrial fibrillation, bypass surgery, cerebral ischaemia, anticoagulation, survival
National Category
Cardiac and Cardiovascular Systems
Identifiers
URN: urn:nbn:se:oru:diva-52180DOI: 10.1080/14017431.2016.1234065PubMedID: 27615545OAI: oai:DiVA.org:oru-52180DiVA: diva2:972627
Available from: 2016-09-21 Created: 2016-09-14 Last updated: 2016-09-26Bibliographically approved

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