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  • 1.
    Alexopoulou, Sofia
    et al.
    Örebro universitet, Institutionen för humaniora, utbildnings- och samhällsvetenskap.
    Fart, Frida
    Örebro universitet, Institutionen för medicinska vetenskaper.
    Jonsson, Ann-Sofie
    Örebro universitet, Restaurang- och hotellhögskolan.
    Karni, Liran
    Örebro universitet, Handelshögskolan vid Örebro Universitet.
    Kenalemang, Lame Maatla
    Örebro universitet, Institutionen för humaniora, utbildnings- och samhällsvetenskap.
    Krishna, Sai
    Örebro universitet, Institutionen för naturvetenskap och teknik.
    Lindblad, Katarina
    Örebro universitet, Musikhögskolan.
    Loutfi, Amy
    Örebro universitet, Institutionen för naturvetenskap och teknik.
    Lundin, Elin
    Örebro universitet, Institutionen för hälsovetenskaper.
    Samzelius, Hanna
    Örebro universitet, Institutionen för humaniora, utbildnings- och samhällsvetenskap.
    Schoultz, Magnus
    Örebro universitet, Institutionen för humaniora, utbildnings- och samhällsvetenskap.
    Spang, Lisa
    Örebro universitet, Institutionen för hälsovetenskaper.
    Söderman, Annika
    Örebro universitet, Institutionen för hälsovetenskaper.
    Tarum, Janelle
    Örebro universitet, Institutionen för hälsovetenskaper.
    Tsertsidis, Antonios
    Örebro universitet, Handelshögskolan vid Örebro Universitet.
    Widell, Bettina
    Örebro universitet, Institutionen för humaniora, utbildnings- och samhällsvetenskap.
    Nilsson, Kerstin (Redaktör)
    Örebro universitet, Institutionen för medicinska vetenskaper.
    Successful ageing in an interdisciplinary context: popular science presentations2018Bok (Övrig (populärvetenskap, debatt, mm))
    Ladda ner fulltext (pdf)
    Omslag
    Ladda ner fulltext (pdf)
    Successful ageing in an interdisciplinary context: popular science presentations
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    presentationsbild
  • 2.
    Edholm, Peter
    et al.
    Örebro universitet, Institutionen för hälsovetenskaper.
    Strandberg, Emelie
    Örebro universitet, Institutionen för hälsovetenskaper.
    Kadi, Fawzi
    Örebro universitet, Institutionen för hälsovetenskaper.
    A healthy diet rich in N-3 PUFAS enhances the effects of resistance training in elderly women2017Konferensbidrag (Refereegranskat)
  • 3.
    Edholm, Peter
    et al.
    Örebro universitet, Institutionen för hälsovetenskaper.
    Strandberg, Emelie
    Örebro universitet, Institutionen för hälsovetenskaper.
    Kadi, Fawzi
    Örebro universitet, Institutionen för hälsovetenskaper.
    A healthy diet rich in N-3 PUFAS enhances the effects of resistance training in elderly women2017Konferensbidrag (Refereegranskat)
  • 4.
    Edvardsson, Bo
    Örebro universitet, Institutionen för juridik, psykologi och socialt arbete.
    ADL (activities of daily living) och inlärningsprinciper1976Övrigt (Övrig (populärvetenskap, debatt, mm))
    Ladda ner fulltext (pdf)
    fulltext
  • 5.
    Edvardsson, Bo
    Örebro universitet, Institutionen för juridik, psykologi och socialt arbete. Högskolan i Örebro, Institutionen för psykologi och pedagogik.
    Försök med geriatrisk aktivering1976Övrigt (Övrigt vetenskapligt)
    Ladda ner fulltext (pdf)
    fulltext
  • 6.
    Edvardsson, Bo
    Örebro universitet, Institutionen för juridik, psykologi och socialt arbete. Högskolan i Örebro, Institutionen för psykologi och pedagogik.
    Metodkatalog för "geriatrisk aktivering"1976Rapport (Övrig (populärvetenskap, debatt, mm))
    Abstract [sv]

    Rapporten utgör en redogörelse för idéer och erfarenheter i enkätsvar från 30 svenska sjukhus 1976. Även ger författaren som är psykolog sina synpunkter kring aktiveringsmetoder. 

    Ladda ner fulltext (pdf)
    fulltext
  • 7.
    Edvardsson, Bo
    Örebro universitet, Institutionen för juridik, psykologi och socialt arbete. Socialhögskolan, Örebro & Ulleråkers sjukhus, Uppsala.
    Om aktivering av geriatriska patienter: Ett principiellt diskussionsunderlag och programskiss för avd 115, Ulleråkers sjukhus1976Övrigt (Övrig (populärvetenskap, debatt, mm))
    Ladda ner fulltext (pdf)
    fulltext
  • 8.
    Edvardsson, Bo
    Örebro universitet, Institutionen för juridik, psykologi och socialt arbete.
    Om över- och understimulering av geriatriska patienter med åtgärdsprinciper1976Rapport (Övrigt vetenskapligt)
    Abstract [sv]

    Ett utbildningsPM använt på Somatisk-geriatriska kliniken Ullåkers sjukhus, Uppsala och som tar upp frågor om över- och understimulering

    Ladda ner fulltext (pdf)
    fulltext
  • 9.
    Engelholm, Anders
    Kommunförbundet i Västernorrland, Härnösand, Sverige.
    Blusi, Madeleine
    FOU, Kommunförbundet i Västernorrland, Härnösand, sverigeVästernorrland.
    Lauritzen, Märta (Medarbetare/bidragsgivare)
    Karolinska Universitetssjukhuset, Stockholm, Sverige.
    Sandberg, Agneta (Medarbetare/bidragsgivare)
    Landstinget Blekinge, Karlskrona, Sverige.
    Malmsten, Kristina
    Blåsdysfunktion hos äldre personer: Indikatorer vid urininkontinens och andra symtom vid vård av äldre personer i särskilt boende eller hemsjukvård2016Rapport (Övrigt vetenskapligt)
    Ladda ner fulltext (pdf)
    fulltext
  • 10.
    Fjellström, Christina
    et al.
    Department of Food, Nutrition and Dietetics, Uppsala University, Uppsala, Sweden.
    Starkenberg, Åsa
    Department of Food, Nutrition and Dietetics, Uppsala University, Uppsala, Sweden.
    Wesslén, Annika
    MEDEA Consultant Bureau, Uppsala, Sweden.
    Tysén Bäckstrom, Ann-Christine
    Department of Geriatrics, Karolinska University Hospital, Huddinge, Sweden.
    Faxén-Irving, Gerd
    Division of Clinical Nutrition, Department of Neurobiology, Care Sciences and Society (NVS), Karolinska Institutet, Huddinge, Sweden; Department of Clinical Nutrition and Dietetics, Karolinska University Hospital, Huddinge, Sweden.
    The OmegAD Study group,
    To Be a Good Food Provider: An Exploratory Study Among Spouses of Persons With Alzheimer's Disease2010Ingår i: American Journal of Alzheimer’s Disease and Other Dementia, ISSN 1533-3175, E-ISSN 1938-2731, Vol. 25, nr 6, s. 521-526Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Large proportions of people with dementia live at home and need help from a relative. The aim of the current study was to examine how people living with persons with Alzheimer's disease (AD) perceived everyday life aspects of food choices, cooking, and food-related work. The analyses are based on focus group interviews including women and men acting as caregivers to people with AD and living in Sweden. The main results identified from the data, were how cohabitants to persons with AD struggle with either taking on a new role as a food provider or extending it, but also how they tried to cope as carer, which entailed food being an important part of the treatment of the disease. Those expressing greatest concern were those perceiving themselves as inexperienced food providers and carers, which in this study were all men.

  • 11.
    Granbom, Marianne
    et al.
    Department of Health Sciences, Lund University, Lund, Sweden.
    Iwarsson, Susanne
    Department of Health Sciences, Lund University, Lund, Sweden.
    Kylberg, Marianne
    Department of Health Sciences, Lund University, Lund, Sweden.
    Pettersson, Cecilia
    Department of Health Sciences, Lund University, Lund, Sweden.
    Slaug, Björn
    Department of Health Sciences, Lund University, Lund, Sweden.
    A public health perspective to environmental barriers and accessibility problems for senior citizens living in ordinary housing2016Ingår i: BMC Public Health, ISSN 1471-2458, E-ISSN 1471-2458, Vol. 16, nr 1, artikel-id 772Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    BACKGROUND: Housing environments that hinder performance of daily activities and impede participation in social life have negative health consequences particularly for the older segment of the population. From a public health perspective accessible housing that supports active and healthy ageing is therefore crucial. The objective of the present study was to make an inventory of environmental barriers and investigate accessibility problems in the ordinary housing stock in Sweden as related to the functional capacity of senior citizens. Particular attention was paid to differences between housing types and building periods and to identify environmental barriers generating the most accessibility problems for sub-groups of senior citizens.

    METHODS: Data on environmental barriers in dwellings from three databases on housing and health in old age was analysed (N = 1021). Four functional profiles representing large groups of senior citizens were used in analyses of the magnitude and severity of potential accessibility problems. Differences in terms of type of housing and building period were examined.

    RESULTS: High proportions of one-family houses as well as multi-dwellings had substantial numbers of environmental barriers, with significantly lower numbers in later building periods. Accessibility problems occurred already for senior citizens with few functional limitations, but more profound for those dependent on mobility devices. The most problematic housing sections were entrances in one-family houses and kitchens of multi-dwellings.

    CONCLUSIONS: Despite a high housing standard in the Swedish ordinary housing stock the results show substantial accessibility problems for senior citizens with functional limitations. To make housing accessible large-scale and systematic efforts are required.

  • 12.
    Granbom, Marianne
    et al.
    Institutionen för hälsovetenskaper, Medicinska fakulteten & Centre for Ageing and Supportive Environments (CASE), Lunds universitet, Lund, Sverige.
    Slaug, Björn
    Institutionen för hälsovetenskaper, Medicinska fakulteten & Centre for Ageing and Supportive Environments (CASE), Lunds universitet, Lund, Sverige.
    Kylberg, Marianne
    Institutionen för hälsovetenskaper, Medicinska fakulteten & Centre for Ageing and Supportive Environments (CASE), Lunds universitet, Lund, Sverige.
    Pettersson, Cecilia
    Institutionen för hälsovetenskaper, Medicinska fakulteten & Centre for Ageing and Supportive Environments (CASE), Lunds universitet, Lund, Sverige.
    Iwarsson, Susanne
    Institutionen för hälsovetenskaper, Medicinska fakulteten & Centre for Ageing and Supportive Environments (CASE), Lunds universitet, Lund, Sverige.
    Inventering av miljöhinder och tillgänglighetsproblem för äldre i bostäder på den ordinarie bostadsmarknaden2015Rapport (Övrigt vetenskapligt)
  • 13.
    James, Inger
    et al.
    Örebro universitet, Institutionen för hälsovetenskaper.
    Norell Pejner, Margaretha
    School of Health and Welfare, Department of Health and Nursing, Halmstad University, Halmstad, Sweden.
    Kihlgren, Annica
    Örebro universitet, Institutionen för hälsovetenskaper.
    Creating conditions for a sense of security during the evenings and nights among older persons receiving home health care in ordinary housing: a participatory appreciative action and reflection study2019Ingår i: BMC Geriatrics, ISSN 1471-2318, E-ISSN 1471-2318, Vol. 19, nr 1, artikel-id 351Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    BACKGROUND: Today many older persons in ordinary housing receive home health care. It is stipulated that the care is to provide security; however, deficiencies in home health care are reported in many countries. It may be difficult to implement a sense of security among older persons receiving home health care in ordinary housing, especially during the evenings and nights, due to a lack of knowledge.

    METHODS: This study is part of a larger project with a participatory appreciative action and reflection (PAAR) approach. We invited older persons, relatives, nurse assistants, registered nurses, and their managers to co-create knowledge with us on how conditions for a sense of security can be created during evenings and nights among older persons receiving home health care in ordinary housing. We performed thematic analysis of the data.

    RESULTS: Five subthemes were developed that gave structure to two main themes. The first main theme, To confirm the self-image, has the following subthemes: To see the home as a reflection of the person's identity and To maintain self-determination. The second main theme, To create interaction in a sheltered place, has these subthemes: To undress the power, To create control and lifelines, and To create a good sleeping environment. The two themes interact and are each other's conditions. The person's self-image must be confirmed in order to create interaction in a sheltered place and through the interaction, the self-image is confirmed.

    CONCLUSION: Conditions necessary for older persons to have a sense of security are living in a familiar environment, having habits and routines maintained, and having self-determination. Other conditions are equality, the prevention of falls, and an individualized sleeping environment. Older people's self-determination should be honored, and they should not being excluded from decision-making. We need to ask them if the conditions are sufficient and their sense of security is great enough to allow them to continue living in their ordinary housing.

  • 14.
    Jansen, Willemijn J.
    et al.
    Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Alzheimer Center Limburg, Maastricht University, Maastricht, the Netherlands.
    Ossenkoppele, Rik
    Department of Neurology and Alzheimer Center, VU University Medical Center, Neuroscience Campus Amsterdam, Amsterdam, the Netherlands; Department of Radiology and Nuclear Medicine, VU University Medical Center, Neuroscience Campus Amsterdam, Amsterdam, the Netherlands; Department of Neurology, Memory and Aging Center, University of California, San Francisco; Helen Wills Neuroscience Institute, University of California, Berkeley.
    Knol, Dirk L.
    Department of Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, the Netherlands.
    Tijms, Betty M.
    Department of Neurology and Alzheimer Center, VU University Medical Center, Neuroscience Campus Amsterdam, Amsterdam, the Netherlands.
    Scheltens, Philip
    Department of Neurology and Alzheimer Center, VU University Medical Center, Neuroscience Campus Amsterdam, Amsterdam, the Netherlands.
    Verhey, Frans R. J.
    Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Alzheimer Center Limburg, Maastricht University, Maastricht, the Netherlands.
    Visser, Pieter Jelle
    Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Alzheimer Center Limburg, Maastricht University, Maastricht, the Netherlands; Department of Neurology and Alzheimer Center, VU University Medical Center, Neuroscience Campus Amsterdam, Amsterdam, the Netherlands.
    The Amyloid Biomarker Study Group,
    Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis2015Ingår i: Journal of the American Medical Association (JAMA), ISSN 0098-7484, E-ISSN 1538-3598, Vol. 313, nr 19, s. 1924-1938Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Importance  Cerebral amyloid-β aggregation is an early pathological event in Alzheimer disease (AD), starting decades before dementia onset. Estimates of the prevalence of amyloid pathology in persons without dementia are needed to understand the development of AD and to design prevention studies.

    Objective  To use individual participant data meta-analysis to estimate the prevalence of amyloid pathology as measured with biomarkers in participants with normal cognition, subjective cognitive impairment (SCI), or mild cognitive impairment (MCI).

    Data Sources  Relevant biomarker studies identified by searching studies published before April 2015 using the MEDLINE and Web of Science databases and through personal communication with investigators.

    Study Selection  Studies were included if they provided individual participant data for participants without dementia and used an a priori defined cutoff for amyloid positivity.

    Data Extraction and Synthesis  Individual records were provided for 2914 participants with normal cognition, 697 with SCI, and 3972 with MCI aged 18 to 100 years from 55 studies.

    Main Outcomes and Measures  Prevalence of amyloid pathology on positron emission tomography or in cerebrospinal fluid according to AD risk factors (age, apolipoprotein E [APOE] genotype, sex, and education) estimated by generalized estimating equations.

    Results  The prevalence of amyloid pathology increased from age 50 to 90 years from 10% (95% CI, 8%-13%) to 44% (95% CI, 37%-51%) among participants with normal cognition; from 12% (95% CI, 8%-18%) to 43% (95% CI, 32%-55%) among patients with SCI; and from 27% (95% CI, 23%-32%) to 71% (95% CI, 66%-76%) among patients with MCI. APOE-ε4 carriers had 2 to 3 times higher prevalence estimates than noncarriers. The age at which 15% of the participants with normal cognition were amyloid positive was approximately 40 years for APOE ε4ε4 carriers, 50 years for ε2ε4 carriers, 55 years for ε3ε4 carriers, 65 years for ε3ε3 carriers, and 95 years for ε2ε3 carriers. Amyloid positivity was more common in highly educated participants but not associated with sex or biomarker modality.

    Conclusions and Relevance  Among persons without dementia, the prevalence of cerebral amyloid pathology as determined by positron emission tomography or cerebrospinal fluid findings was associated with age, APOE genotype, and presence of cognitive impairment. These findings suggest a 20- to 30-year interval between first development of amyloid positivity and onset of dementia.

  • 15.
    Jansen, Willemijn J.
    et al.
    Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Alzheimer Center Limburg, Maastricht University, Maastricht, the Netherlands.
    Visser, Pieter Jelle
    Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Alzheimer Center Limburg, Maastricht University, Maastricht, the Netherlands; Department of Neurology and Alzheimer Center, VU University Medical Center, Neuroscience Campus Amsterdam, Amsterdam, the Netherlands.
    Amyloid Biomarker Study Group,
    Association of Cerebral Amyloid-β Aggregation With Cognitive Functioning in Persons Without Dementia2018Ingår i: JAMA psychiatry, ISSN 2168-6238, E-ISSN 2168-622X, Vol. 75, nr 1, s. 84-95Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Importance: Cerebral amyloid-β aggregation is an early event in Alzheimer disease (AD). Understanding the association between amyloid aggregation and cognitive manifestation in persons without dementia is important for a better understanding of the course of AD and for the design of prevention trials.

    Objective: To investigate whether amyloid-β aggregation is associated with cognitive functioning in persons without dementia.

    Design, Setting, and Participants: This cross-sectional study included 2908 participants with normal cognition and 4133 with mild cognitive impairment (MCI) from 53 studies in the multicenter Amyloid Biomarker Study. Normal cognition was defined as having no cognitive concerns for which medical help was sought and scores within the normal range on cognitive tests. Mild cognitive impairment was diagnosed according to published criteria. Study inclusion began in 2013 and is ongoing. Data analysis was performed in January 2017.

    Main Outcomes and Measures: Global cognitive performance as assessed by the Mini-Mental State Examination (MMSE) and episodic memory performance as assessed by a verbal word learning test. Amyloid aggregation was measured with positron emission tomography or cerebrospinal fluid biomarkers and dichotomized as negative (normal) or positive (abnormal) according to study-specific cutoffs. Generalized estimating equations were used to examine the association between amyloid aggregation and low cognitive scores (MMSE score ≤27 or memory z score≤-1.28) and to assess whether this association was moderated by age, sex, educational level, or apolipoprotein E genotype.

    Results: Among 2908 persons with normal cognition (mean [SD] age, 67.4 [12.8] years), amyloid positivity was associated with low memory scores after age 70 years (mean difference in amyloid positive vs negative, 4% [95% CI, 0%-7%] at 72 years and 21% [95% CI, 10%-33%] at 90 years) but was not associated with low MMSE scores (mean difference, 3% [95% CI, -1% to 6%], P = .16). Among 4133 patients with MCI (mean [SD] age, 70.2 [8.5] years), amyloid positivity was associated with low memory (mean difference, 16% [95% CI, 12%-20%], P < .001) and low MMSE (mean difference, 14% [95% CI, 12%-17%], P < .001) scores, and this association decreased with age. Low cognitive scores had limited utility for screening of amyloid positivity in persons with normal cognition and those with MCI. In persons with normal cognition, the age-related increase in low memory score paralleled the age-related increase in amyloid positivity with an intervening period of 10 to 15 years.

    Conclusions and Relevance: Although low memory scores are an early marker of amyloid positivity, their value as a screening measure for early AD among persons without dementia is limited.

  • 16.
    Kollén, Lena
    et al.
    Örebro universitet, Institutionen för hälsovetenskap och medicin. Department of Physiotherapy and Occupational Therapy, Sahlgrenska University Hospital, Gothenburg, Sweden; Örebro University Centre for Health Care Sciences, Örebro University Hospital, Örebro, Sweden.
    Frändin, Kerstin
    Division of Physiotherapy, Department of Neurobiology, Care Sciences and Society, Karolinska Institute, Stockholm, Sweden.
    Möller, Margareta
    Örebro universitet, Institutionen för hälsovetenskap och medicin. Örebro University Centre for Health Care Sciences, Örebro University Hospital, Örebro, Sweden.
    Fagevik Olsén, Monika
    Department of Physiotherapy and Occupational Therapy, Sahlgrenska University Hospital, Gothenburg, Sweden; Department of Physiotherapy, Clinical of Neuroscience and Physiology, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden.
    Möller, Claes
    Örebro universitet, Institutionen för hälsovetenskap och medicin. Audiological Research Center, Örebro University Hospital, Institute for Disability Research, Örebro, Sweden.
    Benign paroxysmal positional vertigo is a common cause of dizziness and unsteadiness in a large populatioin of 75-year-olds2012Ingår i: Aging Clinical and Experimental Research, ISSN 1594-0667, E-ISSN 1720-8319, Vol. 24, nr 4, s. 317-323Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Background and aims: Studies have shown that 65% of people with dizziness may have a vestibular etiologic diagnosis, possibly benign paroxysmal positional vertigo (BPPV). The diagnosis of BPPV is based on medical history and findings after the Dix-Hallpike test. It is sometimes difficult to perform the Dix-Hallpike test in elderly persons, due to the limited range of motion when extending the neck. In this study, we used a side-lying test to stimulate the posterior semicircular canal, while the head and neck were fully supported on the examination table. The aims of this study were to investigate the prevalence of dizziness and/or impaired balance and BPPV in a population of 75-year-olds by means of a questionnaire and clinical tests, and to compare elderly persons with and without BPPV.

    Methods: A representative population sample of 675 persons completed a questionnaire about dizziness and 571 persons underwent side-lying, static balance and dynamic walking tests.

    Results: Subjective dizziness and/or impaired balance were found in 36% of subjects, especially when walking outdoors. A significant gender difference was found, with a higher prevalence in women (40%) compared with men (30%) (p<0.01). BPPV was found in 11% and was significantly more common in women (p<0.01). Elderly individuals with BPPV also displayed significantly impaired balance in static and dynamic balance tests compared with persons without BPPV (p<0.01). Persons with BPPV reported significantly more subjective problems with dizziness and balance compared with persons without BPPV (p<0.001).

    Conclusions: Subjective and objective unsteadiness, dizziness and BPPV are common in the elderly.

  • 17.
    Kristoffersson, Annica
    et al.
    School of Innovation, Design and Engineering, Mälardalen University, Västerås, Sweden; School of Science and Technology, Örebro University, Örebro, Sweden .
    Kolkowska, Ella
    Örebro universitet, Handelshögskolan vid Örebro Universitet.
    Loutfi, Amy
    Örebro universitet, Institutionen för naturvetenskap och teknik.
    Summative evaluation of a sensor-based cognitive assistive technology: Impact on quality of life and perceived utility2019Ingår i: Gerontechnology, ISSN 1569-1101, E-ISSN 1569-111X, Vol. 18, nr 2, s. 59-69Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Background Current research shows that perceived improvement of quality of life (QoL) is among the most important factors influencing acceptance of technology by older adults.

    Research Aim/question(s) The purpose of this study was to assess the utility of a sensor-based cognitive assistive technology (CAT) deployed in real homes and its impact on older adults’ and their informal caregivers’ perceived QoL.

    Methods During a period of five months, we conducted a summative evaluation by deploying a CAT in the home of couples in which one of the partners had a self-perceived memory decline. We applied a mixed method approach. Quantitative and qualitative data was collected via subjective forms, observations and 28 interviews conducted prior to the deployment, when the CAT was deployed and one month after the CAT removal.

    Results The study showed that the CAT had a psychosocial impact on older adults with a self-perceived memory decline and their informal caregivers but no impact on subjective forms measuring physiological and mental health, anxiety, depression or QoL. Additionally, we found that the CAT lacked a number of functionalities and that the test persons experienced several problems of different nature when using it in their homes. This affected the users’ experienced impact of the CAT.

    Conclusions This study contributes to the literature on sensor networks’ impact on QoL. While previous studies often use general forms intended to assess QoL, this summative evaluation indicates that using such instruments without considering contextual factors is not meaningful. The study also outlines a number of factors that sensor network providers might consider in order to increase their products impact on QoL and their perceived utility.

  • 18.
    Kristoffersson, Annica
    et al.
    Örebro universitet, Institutionen för naturvetenskap och teknik.
    Ulfvarson, Johanna
    Karolinska institutet, Stockholm, Sweden.
    Loutfi, Amy
    Örebro universitet, Institutionen för naturvetenskap och teknik.
    Teknik i hemmet - tekniska förutsättningar2019Ingår i: Hemsjukvård: olika perspektiv på trygg och säker vård / [ed] Mirjam Ekstedt & Maria Flink, Liber, 2019, 1, s. 396-421Kapitel i bok, del av antologi (Övrig (populärvetenskap, debatt, mm))
    Abstract [sv]

    I och med den fjärde industriella revolutionen – Industri 4.0 – kommer en nygeneration av teknik att finnas tillgänglig. Det förutspås att robotik och virtualreality kommer att transformera inte bara arbetsplatser utan även utvecklaandra domäner, såsom smarta städer och möjligheten till livsstils- och hälsomonitoreringhemma.Antalet tillgängliga konsument- och medicintekniska produkter ökar irask takt. Hälso- och sjukvårdssystemet ställs inför utmaningar, såsom behovetav att utveckla verktyg för att hantera ny teknologi men också att förändraarbetsprocesser och anpassa organisationen för att kunna hantera teknologin.

    Det här kapitlet ger en översikt över kommande teknologier, förslag på hurteknologi kan användas i hemmiljöer, en översikt över hur sådan teknik utvärderatssamt inte minst en reflektion kring hur dessa teknologier kan harmoniseramed nuvarande organisatoriska processer.

  • 19.
    Källstrand Eriksson, Jeanette
    et al.
    School of Health and Welfare, Halmstad University, Sweden, Halmstad, Sweden.
    Hildingh, Catherine
    School of Health and Welfare, Halmstad University, Sweden, Halmstad, Sweden.
    Buer, Nina
    Örebro universitet, Institutionen för hälsovetenskaper.
    Thulesius, Hans
    FoU Kronoberg, Växjö, Sweden.
    Seniors' self-preservation by maintaining established self and defying deterioration: A grounded theroy2016Ingår i: International Journal of Qualitative Studies on Health and Well-being, ISSN 1748-2623, E-ISSN 1748-2631, Vol. 11, artikel-id 30265Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    The purpose of this classic grounded theory study was to understand how seniors who are living independently resolve issues influenced by visual impairment and high fall risk. We interviewed and observed 13 seniors with visual impairment in their homes. We also interviewed six visual instructors with experience from many hundreds of relevant incidents from the same group of seniors. We found that the seniors are resolving their main concern of ‘‘remaining themselves as who they used to be’’ by self-preservation. Within this category, the strategies maintaining the established self and defying deterioration emerged as the most prominent in our data. The theme maintaining the established self is mostly guided by change inertia and includes living the past (retaining past activities, reminiscing, and keeping the home intact) and facading (hiding impairment, leading to avoidance of becoming a burden and to risk juggling). Defying deterioration is a proactive scheme and involves moving (by exercising, adapting activities, using walking aids, driving), adapting (by finding new ways), and networking by sustaining old support networks or finding new networks. Self-preservation is generic human behavior and modifying this theory to other fields may therefore be worthwhile. In addition, health care providers may have use for the theory in fall preventive planning.

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  • 20.
    Lindner, Helen Y.
    et al.
    Örebro universitet, Institutionen för hälsovetenskaper.
    Montgomery, Scott
    Örebro universitet, Institutionen för medicinska vetenskaper. Clinical Epidemiology Unit, Department of Medicine, Karolinska Institute, Stockholm, Sweden; Department of Epidemiology and Public Health, University College London, UK.
    Hiyoshi, Ayako
    Örebro universitet, Institutionen för medicinska vetenskaper. Region Örebro län. Department of Public Health Sciences, Stockholm University, Sweden.
    Risk of depression following traumatic limb amputation: a general population-based cohort study2019Ingår i: Scandinavian Journal of Public Health, ISSN 1403-4948, E-ISSN 1651-1905, artikel-id 1403494819868038Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Background: Individuals with traumatic limb amputation (TLA) may be at risk of depression, but evidence of increased depression after TLA from longitudinal studies has been limited. It is also unknown whether physical function, cognitive function, and employment prior to amputation affects depression risk. We aimed to examine longitudinal associations between TLA and depression in working age men, and to explore the role of pre-amputation occupational and individual characteristics.

    Methods: A Swedish national register-based cohort of 189,220 men born between 1952 and 1956, and who attended conscription assessments in adolescence, was followed from 1985 to 2009. Physical, cognitive, and psychological characteristics were measured at the conscription examination, and occupational information was obtained from the 1985 census. Main outcome measures were hospital inpatient and outpatient admissions for depression.

    Results: In total, 401 men underwent TLA; mean age at amputation was 42.5 years (SD 7.4). Cox regression produced an unadjusted hazard ratio (95% confidence interval) of 2.61 (1.62–4.21) for risk of subsequent depression associated with TLA compared with the general population. Adjustment for occupational, physical, cognitive, and psychological characteristics did not change the association much, producing a hazard ratio of 2.53 (1.57–4.08).

    Conclusions: TLA is associated with an increased risk of depression in men over more than two decades of follow up. Occupational and individual characteristics prior to amputation did not greatly change depression risk following amputation. We speculate that a coordinated combination of social support and medical management may help reduce persistent depression risk in men who experience amputation.

  • 21.
    Lundqvist, Stefan
    et al.
    Department of Health and Rehabilitation, Unit of Physiotherapy, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Närhälsan Rehabilitation FaR- teamet central and western Gothenburg, Region Västra Götaland, Gothenburg, Sweden.
    Börjesson, Mats
    Department of Food and Nutrition and Sport Science, Faculty of Education, University of Gothenburg, Gothenburg, Sweden; Institute of Neurosc ience and Physiology, Sahlgrenska Academy, Sahlgrenska University Hospital/Östra, Gothenburg, Sweden.
    Larsson, Maria E. H.
    Department of Health and Rehabilitation, Unit of Physiotherapy, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Närhälsan Research and Development Primary Health Care, Region Västra Götaland, Gothenburg, Sweden.
    Hagberg, Lars
    Örebro universitet, Institutionen för hälsovetenskaper. Region Örebro län. Univ Health Care Research Center, Region Örebro County, Örebro, Sweden.
    Cider, Åsa
    Department of Health and Rehabilitation, Unit of Physiotherapy, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
    Physical Activity on Prescription (PAP), in patients with metabolic risk factors: A 6-month follow-up study in primary health care2017Ingår i: PLoS ONE, ISSN 1932-6203, E-ISSN 1932-6203, Vol. 12, nr 4, artikel-id e0175190Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    There is strong evidence that inadequate physical activity (PA) leads to an increased risk of lifestyle-related diseases and premature mortality. Physical activity on prescription (PAP) is a method to increase the level of PA of patients in primary care, but needs further evaluation. The aim of this observational study was to explore the association between PAP-treatment and the PA level of patients with metabolic risk factors and the relationship between changes in the PA level and health outcomes at the 6 month follow-up. This study included 444 patients in primary care, aged 27-85 years (56% females), who were physically inactive with at least one component of metabolic syndrome. The PAP-treatment model included: individualized dialogue concerning PA, prescribed PA, and a structured follow-up. A total of 368 patients (83%) completed the 6 months of follow-up. Of these patients, 73% increased their PA level and 42% moved from an inadequate PA level to sufficient, according to public health recommendations. There were significant improvements (p <= 0.05) in the following metabolic risk factors: body mass index, waist circumference, systolic blood pressure, fasting plasma glucose, cholesterol, and low density lipoprotein. There were also significant improvements regarding health-related quality of life, assessed by the Short Form 36, in: general health, vitality, social function, mental health, role limitation-physical/emotional, mental component summary, and physical component summary. Regression analysis showed a significant association between changes in the PA level and health outcomes. During the first 6-month period, the caregiver provided PAP support 1-2 times. This study indicates that an individual-based model of PAP-treatment has the potential to change people's PA behavior with improved metabolic risk factors and self-reported quality of life at the 6 month follow-up. Thus, PAP seems to be feasible in a clinical primary care practice, with minimum effort from healthcare professionals.

  • 22.
    Nilsson, Andreas
    et al.
    Örebro universitet, Institutionen för hälsovetenskaper.
    Kadi, Fawzi
    Örebro universitet, Institutionen för hälsovetenskaper.
    Fysisk aktivitet gav positiva effekter på graden av åldersinflammation2018Ingår i: Läkartidningen, ISSN 0023-7205, E-ISSN 1652-7518, Vol. 115, nr 16, s. 720-720, artikel-id E43FArtikel i tidskrift (Refereegranskat)
  • 23.
    Nyström, Markus B. T.
    et al.
    Deparment of Psychology, Umeå University, Umeå, Sweden; The Graduate School in Population Dynamics and Public Policy, Umeå University, Umeå, Sweden.
    Sörman, Daniel E.
    Deparment of Psychology, Umeå University, Umeå, Sweden.
    Kormi-Nouri, Reza
    Örebro universitet, Institutionen för juridik, psykologi och socialt arbete.
    Rönnlund, Michael
    Deparment of Psychology, Umeå University, Umeå, Sweden.
    To what extent is subjective well-being in late adulthood related to subjective and objective memory functioning?: Five-year cross-lagged panel analyses2019Ingår i: Aging & Mental Health, ISSN 1360-7863, E-ISSN 1364-6915, Vol. 23, nr 1, s. 92-99Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    BACKGROUND: Population aging motivated a focus in contemporary research on factors, e.g. cognitive functioning, that contribute to 'aging well.' However, something that has been overlooked is relation between memory functioning, determined by objective tests as well as subjective memory ratings, and subjective well-being (SWB).

    OBJECTIVES: The aim of the present study was to investigate cross-sectional and longitudinal (cross-lagged) relationships between episodic memory (both subjective and objective) and SWB.

    METHOD: A total of 586 older individuals (60-90 years) were assessed on multiple measures of the targeted constructs at baseline (Time 1) as part of the Betula cohort study. Five years later (Time 2), 354 of the participants returned for follow-up measurements and were included in cross-lagged panel analyses.

    RESULTS: As expected, objective memory and subjective memory showed a pattern of cross-sectional age deficits and a mean level longitudinal decline was observed for objective memory. By contrast, SWB showed stable mean levels both across age and time. No cross-sectional or cross-lagged associations were observed between SWB and objective memory, whereas subjective memory and SWB showed a cross-sectional association.

    CONCLUSION: The results underscore that successful aging is a multifaceted construct with no or only weak associations between the investigated components. However, SWB and rate of change at the individual level should be considered to define successful aging.

  • 24.
    Pettersson, Cecilia
    et al.
    Department of Health Sciences, Lund University, Lund, Sweden.
    Jörgensen, Sophie
    Department of Health Sciences, Lund University, Lund, Sweden.
    Mårtensson, Lizette
    Department of Health Sciences, Lund University, Lund, Sweden.
    Lexell, Jan
    Department of Health Sciences, Lund University, Lund, Sweden.
    Slaug, Björn
    Department of Health Sciences, Lund University, Lund, Sweden.
    Iwarsson, Susanne
    Department of Health Sciences, Lund University, Lund, Sweden.
    Mobility Device Use and Exploration of Housing Accessibility for Powered Mobility Device Users among People Ageing with Spinal Cord Injury2013Ingår i: Assistive Technology: From Research to Practice / [ed] Pedro Encarnação, Luís Azevedo, Gert Jan Gelderblom, Alan Newell & Niels-Erik Mathiassen, IOS Press, 2013, Vol. 33, s. 226-232Konferensbidrag (Refereegranskat)
    Abstract [en]

    Aim: To describe the use of mobility devices among people ageing with spinal cord injury (SCI), with a specific focus on use of powered mobility devices (PMD) and housing accessibility.

    Method: Data on the use of walking aids (cane, crutch/es or rollator), manual wheelchair and powered wheelchair/scooter were utilized. To describe functional limitations, environmental barriers and the magnitude of accessibility problems in the home and the closest exterior surroundings for each individual, the Housing Enabler instrument was used. Descriptive statistics were used for data analysis.

    Results: Mobility devices: Among participants with paraplegia, the manual wheelchair was the most frequently used mobility device indoors, and among participants with tetraplegia, it was the PMD. The PMD was the most common mobility device used outdoors among those with tetraplegia, and among participants with paraplegia. Housing accessibility: In exterior surroundings, refuse bin difficult to reach was the environmental barrier that generated the most accessibility problems, while at entrances doors that cannot be fastened in open position was identified as the most severe environmental barrier. Indoors, the environmental barrier that generated the most accessibility problems was wall-mounted cupboard and shelves placed high.

    Conclusion: To enable optimal use of the PMD in the home and close neighborhoods, and support everyday activity and participation for people ageing with SCI, it is vital to take into account not only personal and environmental aspects but also the mobility device in question. Though, it could be discussed if all the environmental barriers identified in this study, actually are problems for users of a PMD, since some of them might be possible to overcome.

  • 25.
    Pettersson, Ingvor
    et al.
    Örebro universitet, Institutionen för hälsovetenskap och medicin.
    Hagberg, Lars
    Örebro universitet, Institutionen för hälsovetenskap och medicin.
    Fredriksson, Carin
    Örebro universitet, Institutionen för hälsovetenskap och medicin.
    Hermansson, Liselotte M N
    Örebro universitet, Institutionen för hälsovetenskap och medicin. Department of Prosthetics and Orthotics, Örebro University Hospital, Örebro, Sweden.
    The effect of powered scooters on activity, participation and quality of life in elderly users2016Ingår i: Disability and Rehabilitation: Assistive Technology, ISSN 1748-3107, E-ISSN 1748-3115, Vol. 11, nr 7, s. 558-563Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Purpose: The aim was to explore the effect of using a powered mobility device (PMD) on older peoples’ activity, participation and quality of life (QoL).

    Method: A pre- and post-intervention design with outcome measures for activity, participation (Individually Prioritized Problem Assessment, IPPA; World Health Organization Disability Assessment Schedule, WHODAS 2.0) and QoL (SF-36) were used. T-test was used to analyse the data. The magnitude of the effects was measured by Cohen’s criteria for effect sizes (d).

    Results: The sample consisted of 45 individuals (36 men) aged 66–88 years referred for prescription of a PMD. All were prescribed a powered scooter (PS). A statistically significant improvement with a large effect on IPPA in the ICF domains of Self-care (d¼2.47), Domestic life (d¼2.40), Interpersonal interactions and relationships (d¼2.08), and Community, social, and civic life (d¼2.36) was found. Medium-sized improvement on the WHODAS 2.0 domain of Participation and small improvements in the SF-36 domains of Physical Health and Role-Physical were also found.

    Conclusion: A PS has significant effects on the areas of activity, participation and QoL in elderly people. These findings have implications for prescriptions of a PS to this population.

  • 26.
    Santini, Sara
    et al.
    Istituto Nazionale di Riposo e Cura per Anziani (INRCA), Ancona, Italy.
    Andersson, Gunnel
    Department of Urology, Örebro University Hospital, Örebro, Sweden.
    Lamura, Giovanni
    Istituto Nazionale di Riposo e Cura per Anziani (INRCA), Ancona, Italy.
    Impact of incontinence on the quality of life of caregivers of older persons with incontinence: a qualitative study in four European Countries2016Ingår i: Archives of gerontology and geriatrics (Print), ISSN 0167-4943, E-ISSN 1872-6976, Vol. 63, s. 92-101Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    The aim of this study was to assess the impact of incontinence management on informal caregivers of older persons with incontinence. In order to investigate this phenomenon in different welfare systems via qualitative interviews and a content analysis methodology, the study was carried out in four European countries (Italy, the Netherlands, Slovak Republic and Sweden). To this purpose, 50 semi-structured interviews were conducted with spouses and children of older people receiving their help to manage the consequences of involuntary urinary and/or faecal leakage. Findings show that incontinence has a remarkably strong effect on caregivers’ quality of life, because it results in progressive social isolation, causing them financial problems as well as psychological and physical exhaustion. The lack of appropriate support and the general silence regarding the problem, which is still considered a taboo by many, aggravate thecaregivers’ situation. It is therefore crucial that caregivers can count on a strong public andprivate support network, appropriate information and suitable incontinent products, in orderto better handle incontinence and care tasks in general.

  • 27.
    Shannon, Oliver M.
    et al.
    Human Nutrition Research Centre, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom.
    Stephan, Blossom C. M.
    Institute of Health and Society and Newcastle University Institute of Ageing, Newcastle University, Newcastle upon Tyne, United Kingdom.
    Granic, Antoneta
    Institute of Health and Society and Newcastle University Institute of Ageing, Newcastle University, Newcastle upon Tyne, United Kingdom.
    Lentjes, Marleen
    Örebro universitet, Institutionen för medicinska vetenskaper. Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.
    Hayat, Shabina
    Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.
    Mulligan, Angela
    Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.
    Brayne, Carol
    Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.
    Khaw, Kay-Tee
    Clinical Gerontology Unit, School of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom.
    Bundy, Rafe
    Department of Nutrition and Preventive Medicine, Norwich Medical School, University of East Anglia, Norwich, United Kingdom.
    Aldred, Sarah
    School of Sport, Exercise, and Rehabilitation Sciences, University of Birmingham, Birmingham, United Kingdom.
    Hornberger, Michael
    Norwich Medical School, University of East Anglia, Norwich Research Park, Norwich, United Kingdom.
    Paddick, Stella-Maria
    Northumbria Healthcare NHS Foundation Trust, North Tyneside General Hospital and Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, United Kingdom.
    Muniz-Tererra, Graciela
    Centre for Dementia Prevention, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom.
    Minihane, Anne-Marie
    Department of Nutrition and Preventive Medicine, Norwich Medical School, University of East Anglia, Norwich, United Kingdom.
    Mathers, John C.
    Human Nutrition Research Centre, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom.
    Siervo, Mario
    Human Nutrition Research Centre, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom; School of Life Sciences, The University of Nottingham Medical School, Queen's Medical Centre, Nottingham, United Kingdom.
    Mediterranean diet adherence and cognitive function in older UK adults: the European Prospective Investigation into Cancer and Nutrition-Norfolk (EPIC-Norfolk) Study2019Ingår i: American Journal of Clinical Nutrition, ISSN 0002-9165, E-ISSN 1938-3207, Vol. 110, nr 4, s. 938-948Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    BACKGROUND: In Mediterranean countries, adherence to a traditional Mediterranean dietary pattern (MedDiet) is associated with better cognitive function and reduced dementia risk. It is unclear if similar benefits exist in non-Mediterranean regions.

    OBJECTIVES: The aims of this study were to examine associations between MedDiet adherence and cognitive function in an older UK population and to investigate whether associations differed between individuals with high compared with low cardiovascular disease (CVD) risk.

    METHODS: We conducted an analysis in 8009 older individuals with dietary data at Health Check 1 (1993-1997) and cognitive function data at Health Check 3 (2006-2011) of the European Prospective Investigation into Cancer and Nutrition-Norfolk (EPIC-Norfolk). Associations were explored between MedDiet adherence and global and domain-specific cognitive test scores and risk of poor cognitive performance in the entire cohort, and when stratified according to CVD risk status.

    RESULTS: Higher MedDiet adherence defined by the Pyramid MedDiet score was associated with better global cognition (β ± SE = -0.012 ± 0.002; P < 0.001), verbal episodic memory (β ± SE = -0.009 ± 0.002; P < 0.001), and simple processing speed (β ± SE = -0.002 ± 0.001; P = 0.013). Lower risk of poor verbal episodic memory (OR: 0.784; 95% CI: 0.641, 0.959; P = 0.018), complex processing speed (OR: 0.739; 95% CI: 0.601, 0.907; P = 0.004), and prospective memory (OR: 0.841; 95% CI: 0.724, 0.977; P = 0.023) was also observed for the highest compared with the lowest Pyramid MedDiet tertiles. The effect of a 1-point increase in Pyramid score on global cognitive function was equivalent to 1.7 fewer years of cognitive aging. MedDiet adherence defined by the Mediterranean Diet Adherence Screener (MEDAS) score (mapped through the use of both binary and continuous scoring) showed similar, albeit less consistent, associations. In stratified analyses, associations were evident in individuals at higher CVD risk only (P < 0.05).

    CONCLUSIONS: Higher adherence to the MedDiet is associated with better cognitive function and lower risk of poor cognition in older UK adults. This evidence underpins the development of interventions to enhance MedDiet adherence, particularly in individuals at higher CVD risk, aiming to reduce the risk of age-related cognitive decline in non-Mediterranean populations.

  • 28.
    Shlisky, Julie
    et al.
    The Sackler Institute for Nutrition Science at the New York Academy of Sciences, New York, NY.
    Bloom, David E.
    Department of Global Health and Population, Harvard TH Chan School of Public Health, Boston, MA.
    Beaudreault, Amy R.
    World Food Center, University of California, Davis, Davis, CA.
    Tucker, Katherine L.
    Department of Clinical Laboratory and Nutritional Sciences, University of Massachusetts Lowell, Lowell, MA.
    Keller, Heather H.
    Schlegel-UW Research Institute for Aging, Applied Health Sciences, University of Waterloo, Ontario, Canada.
    Freund-Levi, Yvonne
    Department of Neurobiology, Care Sciences and Society (NVS), Division of Clinical Geriatrics, Karolinska Institutet, Stockholm, Sweden; Department of Geriatrics, Karolinska University Hospital, Huddinge, Sweden; Department of Psychiatry, Tiohundra Hospital, Stockholm, Sweden.
    Fielding, Roger A.
    Nutrition, Exercise Physiology and Sarcopenia Laboratory and Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA.
    Cheng, Feon W.
    The Pennsylvania State University, University Park, PA, United States.
    Jensen, Gordon L.
    University of Vermont College of Medicine, Burlington, VT, United States.
    Wu, Dayong
    Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA.
    Meydani, Simin N.
    Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA.
    Nutritional Considerations for Healthy Aging and Reduction in Age-Related Chronic Disease2017Ingår i: Advances in Nutrition, ISSN 2161-8313, Vol. 8, nr 1, s. 17-26Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    A projected doubling in the global population of people aged ≥60 y by the year 2050 has major health and economic implications, especially in developing regions. Burdens of unhealthy aging associated with chronic noncommunicable and other age-related diseases may be largely preventable with lifestyle modification, including diet. However, as adults age they become at risk of "nutritional frailty," which can compromise their ability to meet nutritional requirements at a time when specific nutrient needs may be high. This review highlights the role of nutrition science in promoting healthy aging and in improving the prognosis in cases of age-related diseases. It serves to identify key knowledge gaps and implementation challenges to support adequate nutrition for healthy aging, including applicability of metrics used in body-composition and diet adequacy for older adults and mechanisms to reduce nutritional frailty and to promote diet resilience. This review also discusses management recommendations for several leading chronic conditions common in aging populations, including cognitive decline and dementia, sarcopenia, and compromised immunity to infectious disease. The role of health systems in incorporating nutrition care routinely for those aged ≥60 y and living independently and current actions to address nutritional status before hospitalization and the development of disease are discussed.

  • 29.
    Soja, E.
    et al.
    Department of Statistics, Cracow University of Economics, Kraków, Poland.
    Soja, P.
    Department of Informatics, Cracow University of Economics, Kraków, Poland.
    Kolkowska, Ella
    Örebro universitet, Handelshögskolan vid Örebro Universitet.
    Kirikova, M.
    Department of Artificial Intelligence and Systems Engineering, Institute of Applied Computer Systems, Riga Technical University, Riga, Latvia.
    The role of gender in supporting active and healthy ageing by ICT Solutions: Learning from Latvian, Polish and Swedish older adults2020Ingår i: European, Mediterranean, and Middle Eastern Conference on Information Systems, Springer, 2020, Vol. 381, s. 344-357Konferensbidrag (Refereegranskat)
    Abstract [en]

    Facing the challenges related to ageing population with the help of ICT solutions may depend on various socioeconomic factors and differences in attitudes between women and men. This quantitative study investigates the role of gender in the possibility of using ICT for an active and healthy ageing in Latvia, Poland, and Sweden focusing on (1) needs which are considered important for independent and satisfying ageing and (2) technological solutions that should be developed to support independent and healthy ageing. In our approach to statistical data analysis we adopted the ordered logistic model. The findings implicate that gender differences in adoption of ICT for active and healthy ageing may vary between countries. In particular, with respect to the needs, the gender differences appear the greatest in Sweden, while as regards technological solutions, the gender gap is visible only in Poland. The results also show a need to develop some technologies regardless of socioeconomic considerations, such as technologies supporting independent living of elderly women and communication technologies allowing older women to participate in cultural activities.

  • 30.
    Spang, Lisa
    et al.
    Örebro universitet, Institutionen för hälsovetenskaper.
    Holmefur, Marie
    Örebro universitet, Institutionen för hälsovetenskaper.
    Hermansson, Liselotte
    Örebro universitet, Institutionen för hälsovetenskaper.
    Lidström-Holmqvist, Kajsa
    Region Örebro län. Örebro universitet, Institutionen för hälsovetenskaper.
    Factors in daily life leading to the need for moving to a nursing home: Experiences from nursing home applicants2019Konferensbidrag (Övrigt vetenskapligt)
    Abstract [en]

    Background/Aim In Sweden, most people age in ordinary housing, called aging in place. To support aging in place, older people can apply for home-based care such as Meals on Wheels or response alarm .Despite this support, the municipalities receive applications to nursing homes on a daily basis, which indicates that aging in place does not fill everyone’s needs. The aim of this study was to describe what experiences in daily life that make older people aging in place apply for a nursing home.

    Method This study has a descriptive design. Face to face interviews were conducted with older people with declining physical health who had a granted application for a place in a nursing home and were waiting for a placement. Some waited in their homes with or without home-based care and some waited in a short-term facility run by the municipality. Interviews were analyzed by qualitative content analysis according to Elo and Kyngäs.

    Preliminary findings One main category emerged - “To move to a nursing home- a way to regain control over my life”. It was characterized by a feeling of decreasing level of independence which led to experiences of lack of social context or being in a state of dependence where someone else controlled decisions of their lives.  The participants had reached a point where they strongly felt that something has to be done to change their situation. This was usually associated with a critical event such as a hospitalization or after been informed of a cancer diagnosis. These experiences are described by three generic categories with seven subcategories.  The generic categories are “The opportunity to belong to a context”, “A state of dependence” and “Reaching a turning point”.

    Conclusions The findings show that a feeling of lost control due to perceived dependence, falling health or critical everyday life events may lead to a nursing home application. Therefore, in order to enhance aging in place it is important to enable older people to be socially involved, get support to stay as independent as possible in their daily activities and to handle critical events such as hospitalization.

  • 31.
    van de Veen, Roelf
    et al.
    Center of Expertise for Long Term Care, Vilans, Utrecht, The Netherlands.
    Versteeg, Marleen
    Center of Expertise for Long Term Care, Vilans, Utrecht, The Netherlands.
    Mak, Sabina
    Center of Expertise for Long Term Care, Vilans, Utrecht, The Netherlands.
    Bodnarova, Bernadina
    Institute for Labour and Family Research, Staré Mesto, Slovakia.
    Selestiakova, Katarina
    Institute for Labour and Family Research, Staré Mesto, Slovakia.
    Hanson, Elizabeth
    The Swedish National Family Care Competence Centre, Kalmar, Sweden.
    Andersson, Gunnel
    Department of Urology, Örebro University Hospital, Örebro, Sweden.
    Santini, Sara
    INRCA, Italian National Research Centre on Aging, MOPACT EU FP7, University of Sheffield, Sheffield, UK.
    Quattrini, Sabrina
    INRCA, Italian National Research Centre on Aging, MOPACT EU FP7, University of Sheffield, Sheffield, UK.
    Lamura, Giovanni
    INRCA, Italian National Research Centre on Aging, MOPACT EU FP7, University of Sheffield, Sheffield, UK.
    Quality of life of carers managing incontinence in Europe: SURVEY REPORT May 20112011Rapport (Övrigt vetenskapligt)
  • 32.
    Van Eyken, Els
    et al.
    Department of Medical Genetics, University of Antwerp (UA), Antwerp, Belgium.
    Van Camp, Guy V.
    Department of Medical Genetics, University of Antwerp (UA), Antwerp, Belgium.
    Fransen, Erik
    Department of Medical Genetics, University of Antwerp (UA), Antwerp, Belgium.
    Topsakal, Vedat V.
    Department of Otorhinolaryngology, University Hospital of Antwerp (UZA), Antwerp, Belgium.
    Hendrickx, Jan Jaap
    Department of Otorhinolaryngology, University Hospital of Antwerp (UZA), Antwerp, Belgium.
    Demeester, Kelly
    Department of Otorhinolaryngology, University Hospital of Antwerp (UZA), Antwerp, Belgium.
    Van de Heyning, Paul
    Department of Otorhinolaryngology, University Hospital of Antwerp (UZA), Antwerp, Belgium.
    Mäki-Torkko, Elina
    Örebro universitet, Institutionen för medicinska vetenskaper. Department of Otorhinolaryngology, University of Oulu, Oulu, Finland.
    Hannula, Samuli
    Department of Otorhinolaryngology, University of Oulu, Oulu, Finland.
    Sorri, Martti J.
    Department of Otorhinolaryngology, University of Oulu, Oulu, Finland.
    Jensen, Mona
    Department of Audiology, Bispebjerg Hospital (BBH), Copenhagen, Denmark.
    Parving, Agnete
    Department of Audiology, Bispebjerg Hospital (BBH), Copenhagen, Denmark.
    Bille, Michael
    Department of Audiology, Bispebjerg Hospital (BBH), Copenhagen, Denmark.
    Baur, Manuela
    Department of Otorhinolaryngology, University of Tuebingen, Tuebingen, Germany.
    Pfister, Markus H.F.
    Department of Otorhinolaryngology, University of Tuebingen, Tuebingen, Germany.
    Bonaconsa, Amanda
    Department of Oto-surgery, University Hospital Padova, Padova, Italy.
    Mazzoli, Manuela
    Department of Oto-surgery, University Hospital Padova, Padova, Italy.
    Orzan, Eva
    Department of Oto-surgery, University Hospital Padova, Padova, Italy.
    Espeso, Angeles
    Welsh hearing Institute, University Hospital of Wales, Cardiff, UK.
    Stephens, Dafydd
    Welsh hearing Institute, University Hospital of Wales, Cardiff, UK.
    Verbruggen, Katia
    Department of Otorhinolaryngology, University Hospital of Gent (UZ), Gent, Belgium.
    Huyghe, Joke
    Department of Otorhinolaryngology, University Hospital of Gent (UZ), Gent, Belgium.
    Dhooge, Ingeborg
    Department of Otorhinolaryngology, University Hospital of Gent (UZ), Gent, Belgium.
    Huygen, Patrick L.M.
    Department of Otorhinolaryngology, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands.
    Kremer, Hannie Ph .
    Department of Otorhinolaryngology, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands.
    Cremers, Cor Wrj R.J.
    Department of Otorhinolaryngology, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands.
    Kunst, Sylvia J.W.
    Department of Otorhinolaryngology, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands.
    Manninen, Minna
    Department of Otorhinolaryngology, University of Tampere, Tampere, Finland.
    Pyykkö, Ilmari V.
    Department of Otorhinolaryngology, University of Tampere, Tampere, Finland.
    Lacava, Amalia Diaz
    Institute of Medical Biometry, Informatics and Epidemiology, University of Bonn, Germany.
    Steffens, Michael
    Institute of Medical Biometry, Informatics and Epidemiology, University of Bonn, Germany.
    Wienker, Thomas F.
    Institute of Medical Biometry, Informatics and Epidemiology, University of Bonn, Germany.
    Van Laer, Lut
    Department of Medical Genetics, University of Antwerp (UA), Antwerp, Belgium.
    Contribution of the N-acetyltransferase 2 polymorphism NAT2*6A to age-related hearing impairment2007Ingår i: Journal of Medical Genetics, ISSN 0022-2593, E-ISSN 1468-6244, Vol. 44, nr 9, s. 570-578Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    BACKGROUND: Age-related hearing impairment (ARHI) is the most common sensory impairment in older people, affecting 50% of those aged 80 years. The proportion of older people is increasing in the general population, and as a consequence, the number of people affected with ARHI is growing. ARHI is a complex disorder, with both environmental and genetic factors contributing to the disease. The first studies to elucidate these genetic factors were recently performed, resulting in the identification of the first two susceptibility genes for ARHI, NAT2 and KCNQ4.

    METHODS: In the present study, the association between ARHI and polymorphisms in genes that contribute to the defence against reactive oxygen species, including GSTT1, GSTM1 and NAT2, was tested. Samples originated from seven different countries and were combined into two test population samples, the general European population and the Finnish population. Two distinct phenotypes for ARHI were studied, Z(low) and Z(high), representing hearing in the low and high frequencies, respectively. Statistical analysis was performed for single polymorphisms (GSTM1, GSTT1, NAT2*5A, NAT2*6A, and NAT2*7A), haplotypes, and gene-environment and gene-gene interactions.

    RESULTS: We found an association between ARHI and GSTT1 and GSTM1 in the Finnish population sample, and with NAT2*6A in the general European population sample. The latter finding replicates previously published data.

    CONCLUSION: As replication is considered the ultimate proof of true associations in the study of complex disorders, this study provides further support for the involvement of NAT2*6A in ARHI.

  • 33.
    Van Laer, Lut
    et al.
    Department of Medical Genetics, University of Antwerp, Antwerp, Belgium.
    Huyghe, Jeroen R.
    Department of Medical Genetics, University of Antwerp, Antwerp, Belgium.
    Hannula, Samuli
    Department of Otorhinolaryngology, University of Oulu, Oulu, Finland.
    Van Eyken, Els
    Department of Medical Genetics, University of Antwerp, Antwerp, Belgium.
    Stephan, Dietrich A.
    Neurogenomics Division, Translational Genomics Research Institute, Phoenix AZ, United States.
    Mäki-Torkko, Elina
    Örebro universitet, Institutionen för medicinska vetenskaper. Department of Otorhinolaryngology, University of Oulu, Oulu, Finland.
    Aikio, Pekka
    Thule Institute, University of Oulu, Oulu, Finland.
    Fransen, Erik
    Department of Medical Genetics, University of Antwerp, Antwerp, Belgium.
    Lysholm-Bernacchi, Alana
    Neurogenomics Division, Translational Genomics Research Institute, Phoenix AZ, United States.
    Sorri, Martti
    Department of Otorhinolaryngology, University of Oulu, Oulu, Finland.
    Huentelman, Matthew J.
    Neurogenomics Division, Translational Genomics Research Institute, Phoenix AZ, United States.
    Van Camp, Guy
    Department of Medical Genetics, University of Antwerp, Antwerp, Belgium.
    A genome-wide association study for age-related hearing impairment in the Saami2010Ingår i: European Journal of Human Genetics, ISSN 1018-4813, E-ISSN 1476-5438, Vol. 18, nr 6, s. 685-693Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    This study aimed at contributing to the elucidation of the genetic basis of age-related hearing impairment (ARHI), a common multifactorial disease with an important genetic contribution as demonstrated by heritability studies. We conducted a genome-wide association study (GWAS) in the Finnish Saami, a small, ancient, genetically isolated population without evidence of demographic expansion. The choice of this study population was motivated by its anticipated higher extent of LD, potentially offering a substantial power advantage for association mapping. DNA samples and audiometric measurements were collected from 352 Finnish Saami individuals, aged between 50 and 75 years. To reduce the burden of multiple testing, we applied principal component (PC) analysis to the multivariate audiometric phenotype. The first three PCs captured 80% of the variation in hearing thresholds, while maintaining biologically important audiometric features. All subjects were genotyped with the Affymetrix 100 K chip. To account for multiple levels of relatedness among subjects, as well as for population stratification, association testing was performed using a mixed model. We summarised the top-ranking association signals for the three traits under study. The top-ranked SNP, rs457717 (P-value 3.55 x 10(-7)), was associated with PC3 and was localised in an intron of the IQ motif-containing GTPase-activating-like protein (IQGAP2). Intriguingly, the SNP rs161927 (P-value 0.000149), seventh-ranked for PC1, was positioned immediately downstream from the metabotropic glutamate receptor-7 gene (GRM7). As a previous GWAS of a European and Finnish sample set already suggested a role for GRM7 in ARHI, this study provides further evidence for the involvement of this gene.

  • 34.
    Van Laer, Lut
    et al.
    Department of Medical Genetics, University of Antwerp, Antwerp, Belgium.
    Van Eyken, Els
    Department of Medical Genetics, University of Antwerp, Antwerp, Belgium.
    Fransen, Erik
    Department of Medical Genetics, University of Antwerp, Antwerp, Belgium.
    Huyghe, Jeroen R.
    Department of Medical Genetics, University of Antwerp, Antwerp, Belgium.
    Topsakal, Vedat
    Department of Otorhinolaryngology, University Hospital of Antwerp, Antwerp, Belgium.
    Hendrickx, Jan-Jaap
    Department of Otorhinolaryngology, University Hospital of Antwerp, Antwerp, Belgium; Department of Otorhinolaryngology, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands.
    Hannula, Samuli
    Department of Otorhinolaryngology, University of Oulu, Oulu, Finland.
    Mäki-Torkko, Elina
    Örebro universitet, Institutionen för medicinska vetenskaper. Department of Otorhinolaryngology, University of Oulu, Oulu, Finland.
    Jensen, Mona
    Department of Audiology, Bispebjerg Hospital, Copenhagen, Denmark.
    Demeester, Kelly
    Department of Otorhinolaryngology, University Hospital of Antwerp, Antwerp, Belgium.
    Baur, Manuela
    Department of Otorhinolaryngology, University of Tübingen, Tübingen, Germany.
    Bonaconsa, Amanda
    Department of Oto-Surgery, University Hospital Padova, Padova, Italy.
    Mazzoli, Manuela
    Department of Oto-Surgery, University Hospital Padova, Padova, Italy.
    Espeso, Angeles
    Welsh Hearing Institute, Cardiff University, Cardiff, United Kingdom.
    Verbruggen, Katia
    Department of Otorhinolaryngology, University Hospital of Ghent, Ghent, Belgium.
    Huyghe, Joke
    Department of Otorhinolaryngology, University Hospital of Ghent, Ghent, Belgium.
    Huygen, Patrick
    Department of Otorhinolaryngology, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands.
    Kunst, Sylvia
    Department of Otorhinolaryngology, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands.
    Manninen, Minna
    Department of Otorhinolaryngology, University of Tampere, Tampere, Finland.
    Konings, Annelies
    Department of Medical Genetics, University of Antwerp, Antwerp, Belgium.
    Diaz-Lacava, Amalia N.
    Institute of Medical Biometry, Informatics and Epidemiology, University of Bonn, Bonn, Germany.
    Steffens, Michael
    Institute of Medical Biometry, Informatics and Epidemiology, University of Bonn, Bonn, Germany.
    Wienker, Thomas F.
    Institute of Medical Biometry, Informatics and Epidemiology, University of Bonn, Bonn, Germany.
    Pyykkö, Ilmari
    Department of Otorhinolaryngology, University of Tampere, Tampere, Finland.
    Cremers, Cor W. R. J.
    Department of Otorhinolaryngology, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands.
    Kremer, Hannie
    Department of Otorhinolaryngology, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands.
    Dhooge, Ingeborg
    Department of Otorhinolaryngology, University Hospital of Ghent, Ghent, Belgium.
    Stephens, Dafydd
    Welsh Hearing Institute, Cardiff University, Cardiff, United Kingdom.
    Orzan, Eva
    Department of Oto-Surgery, University Hospital Padova, Padova, Italy.
    Pfister, Markus
    Department of Otorhinolaryngology, University of Tübingen, Tübingen, Germany.
    Bille, Michael
    Department of Audiology, Bispebjerg Hospital, Copenhagen, Denmark.
    Parving, Agnete
    Department of Audiology, Bispebjerg Hospital, Copenhagen, Denmark.
    Sorri, Martti
    Department of Otorhinolaryngology, University of Oulu, Oulu, Finland.
    Van de Heyning, Paul H.
    Department of Otorhinolaryngology, University Hospital of Antwerp, Antwerp, Belgium.
    Van Camp, Guy
    Department of Medical Genetics, University of Antwerp, Antwerp, Belgium.
    The grainyhead like 2 gene (GRHL2), alias TFCP2L3, is associated with age-related hearing impairment2008Ingår i: Human Molecular Genetics, ISSN 0964-6906, E-ISSN 1460-2083, Vol. 17, nr 2, s. 159-169Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Age-related hearing impairment (ARHI) is the most prevalent sensory impairment in the elderly. ARHI is a complex disease caused by an interaction between environmental and genetic factors. The contribution of various environmental factors has been relatively extensively studied. In contrast, investigations to identify the genetic risk factors have only recently been initiated. In this paper we describe the results of an association study performed on 2418 ARHI samples derived from nine centers from seven European countries. In 70 candidate genes, a total of 768 tag single nucleotide polymorphisms (SNPs) were selected based on HAPMAP data. These genes were chosen among the monogenic hearing loss genes identified in mice and men in addition to several strong functional candidates. After genotyping and data polishing, statistical analysis of all samples combined resulted in a P-value that survived correction for multiple testing for one SNP in the GRHL2 gene. Other SNPs in this gene were also associated, albeit to a lesser degree. Subsequently, an analysis of the most significant GRHL2 SNP was performed separately for each center. The direction of the association was identical in all nine centers. Two centers showed significant associations and a third center showed a trend towards significance. Subsequent fine mapping of this locus demonstrated that the majority of the associated SNPs reside in intron 1. We hypothesize that the causative variant may change the expression levels of a GRHL2 isoform.

  • 35.
    Winberg, C.
    et al.
    Department of Health Sciences, Lund University, Lund, Sweden.
    Kylberg, M.
    Department of Health Sciences, Lund University, Lund, Sweden.
    Pettersson, Cecilia
    Department of Architecture and Civil Engineering, Chalmers University of Technology, Gothenburg, Sweden.
    Harnett, T.
    School of Social Work, Lund University, Lund, Sweden.
    Hedvall, P.-O.
    Department of Design Sciences, Lund University, Lund, Sweden.
    Mattsson, T.
    Department of Law, Lund University, Lund, Sweden.
    Månsson Lexell, E.
    Department of Neurology and Rehabilitation Medicine, Skåne University Hospital, Lund-Malmö, Sweden.
    The Use of Apps for Health in Persons with Multiple Sclerosis, Parkinson's Disease and Stroke: Barriers and Facilitators2017Ingår i: Harnessing the Power of Technology to Improve Lives / [ed] Cudd, P DeWitte, L, IOS Press, 2017, s. 638-641Konferensbidrag (Refereegranskat)
    Abstract [en]

    Introduction: The importance of mobile health has increased during recent years but few studies have described the use of apps among persons with neurological disabilities.

    Aim: The aim of this paper was to describe how persons ageing with a neurological disability experience barriers and facilitators in relation to using apps in everyday life.

    Method: A qualitative approach was used. 16 persons with neurological disorders participated in two group discussions. Data were analyzed by content analysis.

    Results: The analysis formed four categories; Impairments make apps harder to use, Use of apps is increased by learnability and sharing, Valuating the information in an app, and Apps act supportive and motivating.

    Conclusion: The participants used apps in the same way as persons without disabilities. Impairments and trustworthiness were perceived as barriers, which need to be acknowledged when developing apps for this population. Use of apps was facilitated by the possibility to share data and to connect with others. Apps may have the potential to improve self-management for persons ageing with disabilities but further research is needed.

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