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  • 1.
    Alfaro-Moreno, Ernesto
    et al.
    Örebro University, School of Science and Technology.
    Quintana-Belmares, R.
    Instituto Nacional de Cancerologia, Investigacion Basica, Mexico City, Mexico.
    Montiel-Davalos, A.
    Instituto Nacional de Cancerologia, Investigacion Basica, Mexico City, Mexico.
    Gustafsson, A.
    Örebro University, Man-Technology-Environment Research Center, Örebro, Sweden.
    Miranda, J.
    Universidad Nacional Autonoma de Mexico, Instituto de Fisica, Mexico City, Mexico.
    Lopez-Marure, R.
    Instituto Nacional de Cardiologia, Investigacion, Mexico City, Mexico.
    Rosas-Perez, I.
    Universidad Nacional Autonoma de Mexico, Centro de Ciencias de la Atmosfera, Mexico City, Mexico.
    Expression of receptors for adhesion molecules in monocytes exposed to urban particulate matter is independent of size and composition of the particles2019In: Toxicology Letters, ISSN 0378-4274, E-ISSN 1879-3169, Vol. 314, no Suppl., p. S232-S233Article in journal (Other academic)
  • 2.
    Ax, Erika
    et al.
    Uppsala Univeristy, Uppsala, Sweden.
    Salihovic, Samira
    Örebro University, School of Science and Technology.
    Lind, P. Monica
    Occupational & Environmental Medicine, Uppsala University, Uppsala, Sweden.
    van Bavel, Bert
    Örebro University, School of Science and Technology.
    Lind, Lars
    Acute & Internal Medicine, Uppsala University, Uppsala, Sweden.
    Lampa, Erik
    Occupational & Environmental Medicine, Uppsala University, Uppsala, Sweden.
    Sjögren, Per
    Clinical Nutrition & Metabolism, Uppsala University, Uppsala, Sweden.
    Circulating levels of environmental contaminants are associated with dietary pattern2012In: Toxicology Letters, ISSN 0378-4274, E-ISSN 1879-3169, Vol. 211, no Supplement, p. S101-S101Article in journal (Refereed)
  • 3.
    Lampa, Erik
    et al.
    Uppsala University, Uppsala, Sweden.
    Lind, Lars
    Dept. of Medicine, Uppsala University, Uppsala, Sweden.
    Salihovic, Samira
    Örebro University, School of Science and Technology.
    van Bavel, Bert
    Örebro University, School of Science and Technology.
    Lind, P. Monica
    Occupt and Environ Med, Uppsala University, Uppsala, Sweden.
    Mixtures of environmental contaminants and the metabolic syndrome2012In: Toxicology Letters, ISSN 0378-4274, E-ISSN 1879-3169, Vol. 211, no Supplement, p. S35-, article id OS1-2Article in journal (Refereed)
  • 4.
    Larsson, Maria
    et al.
    Örebro University, School of Science and Technology.
    Orbe, Dan
    MTM Research Centre, Sweden.
    Engwall, Magnus
    Örebro University, School of Science and Technology.
    Ah receptor activating capacity of polycyclic aromatic hydrocarbon derivatives2012In: Toxicology Letters, ISSN 0378-4274, E-ISSN 1879-3169, Vol. 211, no Supplement, p. s127-, article id P16-18Article in journal (Refereed)
  • 5.
    Lind, L.
    et al.
    Uppsala University, Uppsala, Sweden.
    Salihovic, Samira
    Örebro University, School of Science and Technology. Uppsala University, Uppsala, Sweden.
    Van Bavel, Bert
    Örebro University, School of Science and Technology.
    Lind, M.
    Uppsala University, Uppsala, Sweden.
    Circulating levels of perfluorinated compounds and left ventricular geometry2015In: Toxicology Letters, ISSN 0378-4274, E-ISSN 1879-3169, Vol. 238, no 2, p. S93-S93Article in journal (Other academic)
  • 6.
    Lind, Lars
    et al.
    Uppsala University, Uppsala, Sweden.
    Nordfors, Louise
    Karolinska Institutet, Stockholm, Sweden.
    Luttrop, Karin
    Karolinska Institutet, Stockholm, Sweden.
    Syvänen, Ann-Christine
    Dep of Medicine, Uppsala University, Uppsala, Sweden.
    Salihovic, Samira
    Örebro University, School of Science and Technology.
    van Bavel, Bert
    Örebro University, School of Science and Technology.
    Lind, P. Monica
    Occup and Environ Medicine, Uppsala University, Uppsala, Sweden.
    DNA methylation and persistent organic pollutants2012In: Toxicology Letters, ISSN 0378-4274, E-ISSN 1879-3169, Vol. 211, no Supplement, p. S82-Article in journal (Refereed)
  • 7. Lind, Lars
    et al.
    Salihovic, Samira
    Örebro University, School of Science and Technology.
    van Bavel, Bert
    Örebro University, School of Science and Technology.
    Riserius, Ulf
    Lind, P. Monica
    An environmental and life-style wide association study (ELWAS) approach2012In: Toxicology Letters, ISSN 0378-4274, E-ISSN 1879-3169, Vol. 211, no Supplement, p. S81-S81Article in journal (Refereed)
  • 8.
    Lind, M.
    et al.
    Occupational and Environmental Medicine, Uppsala University, Uppsala, Sweden.
    Salihovic, Samira
    Örebro University, School of Science and Technology. Department of Medicine, Uppsala University, Uppsala, Sweden.
    Larsson, A.
    Department of Clinical Chemistry, Uppsala University, Uppsala, Sweden.
    van Bavel, Bert
    Örebro University, School of Science and Technology.
    Lind, L.
    Department of Medicine, Uppsala University, Uppsala, Sweden.
    Circulating levels of perfluoroalkyl substances and biomarkers of liver function in a large population based sample of elderly men and women from Sweden2015In: Toxicology Letters, ISSN 0378-4274, E-ISSN 1879-3169, Vol. 238, no 2, p. S91-S91Article in journal (Other academic)
    Abstract [en]

    Objective: Since perfluoroalkyl substances (PFAS), also called perfluorinated compounds (PFCs), have been shown to accumulate in the liver in experimental studies, we investigated the relationships between PFAS and biomarkers of liver function in the general population.

    Methods: 1016 subjects aged 70 years were investigated in the Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS) study. Eight PFAS were detected in almost all participants era by liquid chromatograph/tandem mass spectrometry. Several biomarkers of liver function were measured in parallel.

    Results: Bilirubin levels were significantly related to several of the PFAS, like perfluoroheptanoic acid (PFHpA), perfluorooctanoicacid (PFOA), perfluorononanoic acid (PFNA), perfluorodecanoic acid (PFDA), and perfluoroundecanoic acid (PFUnDA). Of those, PFHpA, PFOA, PFDA, and PFNA were also related to Alanine Aminotransferase (ALT) levels. PFNA and PFUnDA were inversely related to alkaline phosphatases, while only PFHpA levels were significantly related to gamma-glutamyl transferase (GGT) levels. All associations were adjusted for life-style factors, like smoking, education, exercise habits, energy and alcohol intake.

    Conclusion: Circulating level of PFAS were related to biomarkers of liver function in this population-based sample, suggesting that PFAS could have a negative effect on liver function also in humans.

  • 9.
    Lind, Monica
    et al.
    Uppsala University, Uppsala, Sweden.
    Roos, Vendela
    Occ and Env Med, Uppsala University, Uppsala, Sweden.
    Rönn, Monika
    Occ and Env Med, Uppsala University, Uppsala, Sweden.
    Salihovic, Samira
    Örebro University, School of Science and Technology.
    van Bavel, Bert
    Örebro University, School of Science and Technology.
    Ahlström, Håkan
    Department of Radiolog, Uppsala University, Uppsala, Sweden.
    Johansson, Lars
    Department of Radiolog, Uppsala University, Uppsala, Sweden.
    Kullberg, Joel
    Department of Radiolog, Uppsala University, Uppsala, Sweden.
    Lind, Lars
    Department of Medicine, Uppsala University, Uppsala, Sweden.
    Persistent organic pollutants and adipose tissue distribution2012In: Toxicology Letters, ISSN 0378-4274, E-ISSN 1879-3169, Vol. 211, no Supplement, p. S82-, article id P11-09Article in journal (Refereed)
  • 10.
    Lind, P. Monica
    et al.
    Uppsala University, Uppsala, Sweden.
    Salihovic, Samira
    Örebro University, School of Science and Technology.
    van Bavel, Bert
    Örebro University, School of Science and Technology.
    Lind, Lars
    Department of Medicine, Uppsala University, Uppsala, Sweden.
    Circulating levels of pp-DDE and hypertension2012In: Toxicology Letters, ISSN 0378-4274, E-ISSN 1879-3169, Vol. 211, no Supplement, p. S83-, article id P11-12Article in journal (Refereed)
  • 11.
    Sjöberg Lind, Ylva
    et al.
    Linköping University Hospital, Linköping, Sweden.
    Lind, P. Monica
    Occup and Environ Medicine, Uppsala University, Uppsala, Sweden.
    Salihovic, Samira
    Örebro University, School of Science and Technology.
    van Bavel, Bert
    Örebro University, School of Science and Technology.
    POPs are associated with left ventricular systolic and diastolic dysfunction2012In: Toxicology Letters, ISSN 0378-4274, E-ISSN 1879-3169, Vol. 211, no Supplement, p. S83-, article id P11-13Article in journal (Refereed)
  • 12.
    Söderqvist, Fredrik
    et al.
    Örebro University, School of Health and Medical Sciences.
    Carlberg, Michael
    Universitetssjukhuset Örebro.
    Hansson Mild, Kjell
    Umeå universitet.
    Hardell, Lennart
    Örebro University, School of Health and Medical Sciences.
    Exposure to an 890-MHz mobile phone-like signal and serum levels of S100B and transthyretin in volunteers2009In: Toxicology Letters, ISSN 0378-4274, E-ISSN 1879-3169, Vol. 189, no 1, p. 63-66Article in journal (Refereed)
    Abstract [en]

    Whether low-intensity non-thermal microwave radiation alters the integrity of the blood-brain barrier has been debated since the late 1970s, yet no experimental study has been carried out on humans. The aim of this study was to test, using peripheral markers, whether exposure to a mobile phone-like signal alters the integrity of the human blood-brain and blood-cerebrospinal fluid barriers. A provocation study was carried out that exposed 41 volunteers to a 30 min GSM 890 MHz signal with an average specific energy absorption rate distribution of 1.0 W/kg in the temporal area of the head as measured over any 1g of contiguous tissue. The outcome was assessed by changes in serum concentrations of two putative markers of brain barrier integrity, S100B and transthyretin. Repeated blood sampling before and after the provocation showed no statistically significant increase in the serum levels of S100B, while for transthyretin a statistically significant increase was seen in the final blood sample 60 min after the end of the provocation as compared to the prior sample taken immediately after provocation (p=0.02). The clinical significance of this finding, if any, is unknown. Further randomized studies with use of additional more brain specific markers are needed.

  • 13.
    Söderqvist, Fredrik
    et al.
    Centre for Clinical Research, Uppsala University, Västerås Hospital, Västerås, Sweden.
    Carlberg, Michael
    Department of Oncology, Faculty of Medicine and Health, Örebro University, Örebro, Sweden .
    Hardell, Lennart
    Department of Oncology, Faculty of Medicine and Health, Örebro University, Örebro, Sweden .
    Biomarkers in volunteers exposed to mobile phone radiation2015In: Toxicology Letters, ISSN 0378-4274, E-ISSN 1879-3169, Vol. 235, no 2, p. 140-146Article in journal (Refereed)
    Abstract [en]

    For some time it has been investigated whether low-intensity non-thermal microwave radiation from mobile phones adversely affects the mammalian blood-brain barrier (BBB). All such studies except one have been either in vitro or experimental animal studies. The one carried out on humans showed a statistically significant increase in serum transthyretin (TTR) 60 min after finishing of a 30-min microwave exposure session. The aim of the present study was to follow up on the finding of the previous one using a better study design. Using biomarkers analyzed in blood serum before and after the exposure this single blinded randomized counterbalanced study, including 24 healthy subjects aged 18-30 years that all underwent three exposure conditions (SAR(10G) = 2 W/kg, SAR(10G) = 0.2 W/kg, sham), tested whether microwaves from an 890-MHz phone-like signal give acute effects on the integrity of brain-shielding barriers. Over time, statistically significant variations were found for two of the three biomarkers (TTR; beta-trace protein); however, no such difference was found between the different exposure conditions nor was there any interaction between exposure condition and time of blood sampling. In conclusion this study failed to show any acute clinically or statistically significant effect of short term microwave exposure on the serum levels of S100 beta, TTR and b-trace protein with a follow up limited to two hours. The study was hampered by the fact that all study persons were regular wireless phone users and thus not naive as to microwave exposure. (C) 2015 Elsevier Ireland Ltd. All rights reserved.

  • 14.
    Westman, Ola
    et al.
    Örebro University, School of Science and Technology.
    Nordén, Marcus
    Örebro University, School of Science and Technology.
    Larsson, Maria
    Örebro University, School of Science and Technology.
    Venizelos, Nikolaos
    Örebro University, School of Science and Technology.
    Hollert, Henner
    RWTH Aachen University, Aachen, Germany.
    Engwall, Magnus
    Örebro University, School of Science and Technology.
    Reduced beta-oxidation in avian following exposure of polycyclic aromatic hydrocarbons2012In: Toxicology Letters, ISSN 0378-4274, E-ISSN 1879-3169, Vol. 211, no Supplement, p. s86-s87Article in journal (Refereed)
1 - 14 of 14
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