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  • 1.
    Nygren, Heli
    et al.
    VTT Technical Research Centre of Finland, Espoo, Finland.
    Pöhö, Päivi
    VTT Technical Research Centre of Finland, Espoo, Finland.
    Seppänen-Laakso, Tuulikki
    VTT Technical Research Centre of Finland, Espoo, Finland.
    Lahtinen, Ulla
    VTT Technical Research Centre of Finland, Espoo, Finland.
    Oresic, Matej
    VTT Technical Research Centre of Finland, Espoo, Finland.
    Hyötyläinen, Tuulia
    VTT Technical Research Centre of Finland, Espoo, Finland.
    Ultrahigh-performance liquid chromatography-mass spectrometry in Lipidomics2014In: LC GC North America, ISSN 1527-5949, E-ISSN 1939-1889, Vol. 32, no 4, p. 286-293Article in journal (Refereed)
    Abstract [en]

    An analytical method for the global profiling of molecular lipids in biological samples, with particular emphasis on the plasmalogen lipids, is described. The global profiling method is based on ultrahigh-performance liquid chromatography combined with quadrupole time-of-flight-mass spectrometry (UHPLC-QTOE-MS). The profiling approach is complemented by UHPLC-LTQ-Orbitrap mass spectrometry in MSn mode for de novo lipid identification.

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