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  • 1.
    Aaboen, Lise
    et al.
    Department of Industrial Economics and Technology Management, Norwegian University of Science and Technology, Trondheim, Norway.
    Laage-Hellman, Jens
    Department of Technology Management and Economics, Chalmers University of Technology, Gothenburg, Sweden.
    Lind, Frida
    Department of Technology Management and Economics, Chalmers University of Technology, Gothenburg, Sweden.
    Öberg, Christina
    Örebro University, Örebro University School of Business.
    Shih, Tommy
    Department of Business Administration, Lund University, Lund, Sweden.
    Exploring the roles of university spin-offs in business networks2016In: Industrial Marketing Management, ISSN 0019-8501, E-ISSN 1873-2062, Vol. 59, p. 157-166Article in journal (Refereed)
    Abstract [en]

    This paper identifies different university spin-off (USO) roles related to resource interaction among business parties. It does so by mapping how USOs become part of business networks in terms of their roles relative to other parties. The theoretical frame of reference focuses on roles and resource interaction based on an industrial network approach to business markets. The empirical research is based onfive cases of USOs representing a variety in terms of technology, degree of newness, sector, and area of application. As a result of the analysis, three different roles are identified: the USO as resource mediator, resource re-combiner and resource renewer. These roles reflect how USOs adapt resources to, or require changes among, business parties' resources. The paper also discusses the main resource interfaces associated with the three roles and related challenges. The paper contributes to previous research through illustrating USOs' roles relative to business parties from a resource interaction point of view, and by pointing to the establishment of new companies in business networks as a way of implementing innovation. Finally, the paper discusses the managerial implications of the research in terms of the USO's need to understand which role to take and how to develop it.

  • 2. AAboen, Lise
    et al.
    Laage-Hellman, Jens
    Chalmers University of technology, Gothenburg, Sweden.
    Lind, Frida
    Chalmers University of technology, Gothenburg, Sweden.
    Öberg, Christina
    Örebro University, Örebro University School of Business.
    Shih, Tommy
    Lund University, Lund, Sweden.
    University spin-offs and their roles in business networks2014In: IMP Conference, 2014Conference paper (Refereed)
  • 3.
    Abatecola, Gianpaolo
    et al.
    University of Rome Tor Vergata, Rome, Italy.
    Breslin, Dermot
    Sheffield University Management School, Sheffield, UK.
    Kask, Johan
    Örebro University, Örebro University School of Business.
    Discussing co-evolutionary research in management studies: a critical account of the new millennium2018Conference paper (Refereed)
  • 4.
    Abatecola, Gianpaolo
    et al.
    University of Rome Tor Vergata, Rome, Italy.
    Breslin, Dermot
    University of Sheffield, Sheffield, UK.
    Kask, Johan
    Örebro University, Örebro University School of Business.
    Lo sviluppo dell’approccio co-evolutivo negli studi di management: Un’analisi del nuovo Millennio2018In: Evoluzionismo sistemico: il fascino della precarietà / [ed] Paniccia, P. and Barile S., Aracne , 2018, p. 13-20Conference paper (Other academic)
  • 5.
    Abbas, Asad
    et al.
    Örebro University, Örebro University School of Business.
    Faiz, Ali
    Örebro University, Örebro University School of Business.
    Reasons for the failure of government IT projects in Pakistan: A Contemporary Study2013Independent thesis Advanced level (degree of Master (Two Years)), 10 credits / 15 HE creditsStudent thesis
  • 6.
    Abbas, Asad
    et al.
    Örebro University, Örebro University School of Business.
    Faiz, Ali
    Örebro University, Örebro University School of Business.
    Usefulness of Digital and Traditional Library in Higher Education2012Independent thesis Advanced level (degree of Master (One Year)), 10 credits / 15 HE creditsStudent thesis
  • 7.
    Abdelnour, Samer
    et al.
    Erasmus University, Rotterdam, The Netherlands.
    Hasselbladh, Hans
    Örebro University, Örebro University School of Business.
    Kallinikos, Jannis
    London School of Economics and Political Science, London, UK.
    Agency and Instituions in Organization Studies2017In: Organization Studies, ISSN 0170-8406, E-ISSN 1741-3044, Vol. 38, no 12, p. 1775-1792Article in journal (Refereed)
    Abstract [en]

    Agency and institutions are essential concepts within institutional theory. In this Perspectives issue, we draw on a select group of Organization Studies articles to provide an overview of the topic of agency and institutions. We first consider different ways of defining agency and institutions and examine their implications for institutional theory. We then analyse the relationship of actors and institutions through four lenses – the wilful actor, collective intentionality, patchwork institutions and modular individuals. Our analysis leads us to dissociate agency from individuals and view it as a capacity or quality that stems from resources, rights and obligations tied to the roles and social positions actors occupy. Roles and social positions are institutionally engineered. It is social actors qua occupants of roles and positions (not individuals) that enter the social ‘stage’ and exercise agency.

  • 8.
    Abdulhomeed, Bashar
    Örebro University, Örebro University School of Business.
    Contemporary Research on e-democracy: A Literature Review2013Independent thesis Advanced level (degree of Master (Two Years)), 10 credits / 15 HE creditsStudent thesis
  • 9.
    Abrahamsson, Axel
    et al.
    Örebro University, Örebro University School of Business.
    Nordén, Fredrik
    Örebro University, Örebro University School of Business.
    Värdering till verkligt värde - En kvantitativ studie om företags efterlevnad av upplysningskraven i IFRS 132018Independent thesis Advanced level (degree of Master (Two Years)), 20 credits / 30 HE creditsStudent thesis
  • 10.
    Abrahamsson, Axel
    et al.
    Örebro University, Örebro University School of Business.
    Nordén, Fredrik
    Örebro University, Örebro University School of Business.
    Odenå, Oscar
    Örebro University, Örebro University School of Business.
    Efterlevnadsgraden av IAS 36 p. 134 - Utifrån ett isomorfistiskt perspektiv2016Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
  • 11.
    Abrahamsson, Catrin
    et al.
    Örebro University, Örebro University School of Business.
    Atterfors, Sofia
    Örebro University, Örebro University School of Business.
    Erlandsson, Sofia
    Örebro University, Örebro University School of Business.
    Från ideell förening till hybridorganisation - En kvalitativ studie i elitidrottsföreningar2015Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
  • 12.
    Abrahamsson, Catrin
    et al.
    Örebro University, Örebro University School of Business.
    Blixt, Elizabeth
    Örebro University, Örebro University School of Business.
    Lean - effektivitet och minskning av slöseri till priset av stress?: En kvalitativ studie av teamworks och kommunikationens påverkan på anställdas upplevda stress2016Independent thesis Advanced level (degree of Master (Two Years)), 20 credits / 30 HE creditsStudent thesis
  • 13.
    Abrahamsson, Gun
    et al.
    Örebro University, Örebro University School of Business.
    Englund, Hans
    Örebro University, Örebro University School of Business.
    Gerdin, Jonas
    Örebro University, Örebro University School of Business.
    On the (re)construction of numbers and operational reality: A study of face-to-face interactions2016In: Qualitative Research in Accounting & Management/Emerald, ISSN 1176-6093, E-ISSN 1758-7654, Vol. 13, no 2, p. 159-188Article in journal (Refereed)
    Abstract [en]

    Purpose: This paper aims to examine the mobilization of management accounting (MA) numbers and metrics in social interactions. The purpose is to develop a model of how and why managers perceive and mobilize (new) MA numbers/metrics in a changing way over time in situated face-to-face interactions.

    Design/methodology/approach: An observation-based qualitative field study of a change project in a large manufacturing company is used as the basis for our analysis.

    Findings: The empirical study shows that MA numbers and metrics are essential when semi-distant managers strive to solve problems and achieve radical improvement targets, but that the ways in which existing and new metrics are perceived and mobilized during face-to-face interactions change over time. The study provides both a detailed account of the emergent nature of the transformation process and a number of mechanisms as to why managers (inter-)act the way they do to produce such change.

    Originality/value: The paper problematizes the generally held view that MA numbers and metrics primarily work as a structuring device in face-to-face interactions, and also, how the processes are constituted through which MA is transformed into such a structuring device. The paper also adds new insights to our understandings of why managers (inter-)act the way they do to produce MA change.

  • 14.
    Abrahamsson, Gun
    et al.
    Örebro University, Örebro University School of Business.
    Englund, Hans
    Örebro University, Örebro University School of Business.
    Gerdin, Jonas
    Örebro University, Örebro University School of Business.
    Organizational identity and management accounting change2011In: Accounting, Auditing & Accountability Journal, ISSN 1368-0668, E-ISSN 1758-4205, Vol. 24, no 3, p. 345-376Article in journal (Refereed)
    Abstract [en]

    Purpose – This paper aims to examine how and why management accounting practices are linked to an organization's identity and identity discrepancies.

    Design/methodology/approach – A qualitative field study of a one-year change project in a large manufacturing company is used as the basis for the analysis.

    Findings – The empirical study reveals how discrepancies between organizational members' perceived identity and their construed external (and desired future) image both influence and are influenced by emergent accounting practices. Empirical evidence suggests such a reciprocal relationship between accounting and identity, since accounting practices are an important means of (de)legitimizing an organization's current self-perception.

    Research limitations/implications – The uncovered reciprocal relationship between management accounting practices and organizational identity (discrepancies) have implications for a broader literature, including the works on how different forms of control interact as a “control package” and the discourse on potential sources of organizational identity change.

    Originality/value – Although it has previously been suggested that management accounting may be an important means for, as well as an outcome of, processes of identity (re)constructions in organizations, this study suggests a more complex interplay than has previously been noted in the literature. Specifically, it was found that organizational identity may for a considerable time work as a highly influential and largely unquestioned categorical imperative, signifying the boundaries of appropriate organizational action. At times, however, accounting practices may spark (re)constructions of identity discrepancies through: providing identity-inconsistent evidence; and using (new) measures in a “feed-forward” manner to explore possible ways to close such perceived discrepancies.

  • 15.
    Abrahamsson, Gun
    et al.
    Örebro University, Örebro University School of Business.
    Gerdin, Jonas
    Örebro University, Örebro University School of Business.
    Helin, Sven
    Örebro University, Örebro University School of Business.
    Management accounting and organizational change - an institutional perspective2005Conference paper (Refereed)
  • 16.
    Abrahamsson, Gun
    et al.
    Örebro University, Örebro University School of Business.
    Helin, SvenÖrebro University, Örebro University School of Business.
    Accounting and Continuous Improvements: some notes on how accounting can support or hinder establishment of Continuous Improvements1998Conference proceedings (editor) (Refereed)
  • 17.
    Abrahamsson, Gun
    et al.
    Örebro University, Örebro University School of Business.
    Helin, Sven
    Örebro University, Örebro University School of Business.
    Continuous Improvement-work under Ambiguity: the role of Management Accounting Control2000Conference paper (Refereed)
  • 18.
    Abrahamsson, Gun
    et al.
    Örebro University, Örebro University School of Business.
    Helin, Sven
    Örebro University, Örebro University School of Business.
    Ekonomistyrning och förbättringsarbete: En fallstudie om hur ekonomistyrning kan stödja respektive hindra förbättringsarbete2000Licentiate thesis, monograph (Other academic)
  • 19.
    Abrahamsson, Gun
    et al.
    Örebro University, Örebro University School of Business.
    Helin, Sven
    Örebro University, Örebro University School of Business.
    Hur kan ekonomistyrningen stödja eller hindra ett kontinuerligt och systematiskt förändringsarbete?1999Conference paper (Refereed)
  • 20.
    Abrahamsson, Gun
    et al.
    Örebro University, Örebro University School of Business.
    Helin, Sven
    Örebro University, Örebro University School of Business.
    'It's the singer not the song'- how Management Accounting Influence Problem Solving Activities on Shop Floor Level: a Case Study2001Conference paper (Refereed)
  • 21.
    Abrahamsson, Gun
    et al.
    Örebro University, Örebro University School of Business.
    Johansson, Tobias
    Örebro University, Örebro University School of Business.
    Ekonomiska ansvarsenheter2013In: Perspektiv på ekonomistyrning / [ed] Erik Jannesson, Matti Skoog, Stockholm: Liber, 2013, 1, p. 14-35Chapter in book (Other academic)
  • 22.
    Abrahamsson, Nathalie
    et al.
    Örebro University, Örebro University School of Business.
    Altun, Sultan
    Örebro University, Örebro University School of Business.
    Kundlojalitet En studie om hur en fysisk telefonbutik kan bevara och stärka kundlojalitet 2016Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
  • 23.
    Abrahamsson, Nathalie
    et al.
    Örebro University, Örebro University School of Business.
    Celik, Evelin
    Örebro University, Örebro University School of Business.
    Mati, Mikaela
    Örebro University, Örebro University School of Business.
    Motstånd och bristande engagemang vid en organisationsförändring2017Independent thesis Advanced level (degree of Master (Two Years)), 20 credits / 30 HE creditsStudent thesis
  • 24.
    Abrahamsson, Valensia
    et al.
    Örebro University, Örebro University School of Business.
    Halef, Charbel
    Örebro University, Örebro University School of Business.
    Anställdas motivation inom tillverkningsindustrin: En kvalitativ fallstudie med utgångspunkt i förväntansteorin 2018Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
  • 25.
    Abramsson, Alexander
    et al.
    Örebro University, Örebro University School of Business.
    Happonen, Anna
    Örebro University, Örebro University School of Business.
    Malmsten, Dennis
    Örebro University, Örebro University School of Business.
    Aktieindexobligationer: En studie om struktur och prissättning av produkter på den svenska marknaden2013Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
  • 26.
    Acar, Augin
    et al.
    Örebro University, Örebro University School of Business.
    Törmänen, Anton
    Örebro University, Örebro University School of Business.
    Rosenberg, Daniel
    Örebro University, Örebro University School of Business.
    Legitimitetssökande i en kontroversiell bransch En studie av tre spelbolags hållbarhetsredovisningar2016Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
  • 27.
    Ackfjärd, Rickard
    et al.
    Örebro University, Örebro University School of Business.
    Karlsson, Mattias
    Örebro University, Örebro University School of Business.
    Förslag till ett nytt ramverk för utvärdering och utveckling av ARP-poisoning-skydd2016Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
  • 28.
    Adams, Richard
    et al.
    University of Exeter Business School, Exeter, UK.
    Alexander, Allen
    University of Exeter Business School, Exeter, UK.
    Öberg, Christina
    Örebro University, Örebro University School of Business.
    Innovation management capabilities for start-ups and spin-offs: A literature review2014Conference paper (Refereed)
  • 29.
    Adawi, Ali
    et al.
    Örebro University, Örebro University School of Business.
    Björnius, Emil
    Örebro University, Örebro University School of Business.
    "Den enes bröd, den andres spam" En studie om studenters uppfattning om och mottaglighet till e-postreklam2014Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
  • 30.
    Adawi, Ali
    et al.
    Örebro University, Örebro University School of Business.
    Oguz, Muzaffer
    Örebro University, Örebro University School of Business.
    CSR-relaterade aktiviteter i kontroversiella branscher - Tobaksbolaget Swedish Match legitimitetsförsök mellan 1999-2014.2016Independent thesis Advanced level (degree of Master (Two Years)), 20 credits / 30 HE creditsStudent thesis
  • 31.
    Adlund, Ardalan
    et al.
    Örebro University, Örebro University School of Business.
    Afzali, Shafi
    Örebro University, Örebro University School of Business.
    Rasheed, Pirman
    Örebro University, Örebro University School of Business.
    Motivation En fallstudie kring Systembolaget En fallstudie om motivation och hur det uppfattas av cheferna respektive de anställda.2014Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
  • 32.
    Adolfsson, Emelie
    et al.
    Örebro University, Örebro University School of Business.
    Bergkvist, Sofia
    Örebro University, Örebro University School of Business.
    Bjärkstedt, Anna
    Örebro University, Örebro University School of Business.
    Kvinnliga revisorers avancemang inom revisionsbranschen: En studie om jämställdhet och struktur 2018Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
  • 33.
    Adolfsson, Per
    et al.
    Örebro University, Örebro University School of Business.
    Ivic, Marijo
    Örebro University, Örebro University School of Business.
    Ett försök till att statistiskt modellera matchutfall för fotbollens division 1 för herrar i Sverige2012Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
  • 34.
    Af Robson, Siri
    et al.
    Örebro University, Örebro University School of Business.
    Irhem, Sophie
    Örebro University, Örebro University School of Business.
    Ekologiska aktier - en studie om bolags anslutning till FTSE4Good2016Independent thesis Advanced level (degree of Master (Two Years)), 20 credits / 30 HE creditsStudent thesis
  • 35.
    AF Robson, Siri
    et al.
    Örebro University, Örebro University School of Business.
    Ronell, Kristina
    Örebro University, Örebro University School of Business.
    Generation Y i Restaurangbranschen: Attityder på Arbetsplatsen2014Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
  • 36.
    AGALOMBA, CHRISTINE AFANDI
    Örebro University, Örebro University School of Business.
    Factors contributing to failure of egovernment projects in developing countries: a literature review2012Independent thesis Advanced level (degree of Master (Two Years)), 10 credits / 15 HE creditsStudent thesis
  • 37.
    Age, Oskar
    et al.
    Örebro University, Örebro University School of Business.
    Carlsson, Anna
    Örebro University, Örebro University School of Business.
    Larsson-Torri, Emma
    Örebro University, Örebro University School of Business.
    Vad motiverar redovisningsval?: En litteraturgenomgång från millenniumskiftet fram till idag2018Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
  • 38.
    Agebro, Jessica
    et al.
    Örebro University, Örebro University School of Business.
    Bergetoft, Fanny
    Örebro University, Örebro University School of Business.
    Sponsring av individuella elitidrottare ur ett företagsperspektiv2018Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
  • 39.
    Agewall, Cecilia
    et al.
    Örebro University, Örebro University School of Business.
    Sommarström, Julina
    Örebro University, Örebro University School of Business.
    Legitimitet som en nyckel till acceptans: En studie om legitimitetsskapande2014Independent thesis Advanced level (degree of Master (Two Years)), 20 credits / 30 HE creditsStudent thesis
  • 40.
    Aghanavesi, Somayeh
    et al.
    Computer Engineering, School of Technology and Business Studies, Borlänge, Dalarna University, Sweden.
    Bergquist, Filip
    Dept. of Pharmacology, University of Gothenburg, Gothenburg, Sweden.
    Nyholm, Dag
    Dept. of Neuroscience, Neurology, Uppsala University, Uppsala, Sweden.
    Senek, Marina
    Dept. of Neuroscience, Neurology, Uppsala University, Uppsala, Sweden.
    Memedi, Mevludin
    Örebro University, Örebro University School of Business.
    Objective assessment of Parkinson’s disease motor symptoms during leg agility test using motion sensors2018Conference paper (Refereed)
    Abstract [en]

    Title: Objective assessment of Parkinson’s disease motor symptoms during leg agility test using motion sensors

    Objective: To develop and evaluate machine learning methods for assessment of Parkinson’s disease (PD) motor symptoms using leg agility (LA) data collected with motion sensors during a single dose experiment.

    Background: Nineteen advanced PD patients (Gender: 14 males and 5 females, mean age: 71.4, mean years with PD: 9.7, mean years with levodopa: 9.5) were recruited in a single center, open label, single dose clinical trial in Sweden [1].

    Methods: The patients performed up to 15 LA tasks while wearing motions sensors on their foot ankle. They performed tests at pre-defined time points starting from baseline, at the time they received a morning dose (150% of their levodopa equivalent morning dose), and at follow-up time points until the medication wore off. The patients were video recorded while performing the motor tasks. and three movement disorder experts rated the observed motor symptoms using 4 items from the Unified PD Rating Scale (UPDRS) motor section including UPDRS #26 (leg agility), UPDRS #27 (Arising from chair), UPDRS #29 (Gait), UPDRS #31 (Body Bradykinesia and Hypokinesia), and dyskinesia scale. In addition, they rated the overall mobility of the patients using Treatment Response Scale (TRS), ranging from -3 (very off) to 3 (very dyskinetic). Sensors data were processed and their quantitative measures were used to develop machine learning methods, which mapped them to the mean ratings of the three raters. The quality of measurements of the machine learning methods was assessed by convergence validity, test-retest reliability and sensitivity to treatment.

    Results: Results from the 10-fold cross validation showed good convergent validity of the machine learning methods (Support Vector Machines, SVM) with correlation coefficients of 0.81 for TRS, 0.78 for UPDRS #26, 0.69 for UPDRS #27, 0.78 for UPDRS #29, 0.83 for UPDRS #31, and 0.67 for dyskinesia scale (P<0.001). There were good correlations between scores produced by the methods during the first (baseline) and second tests with coefficients ranging from 0.58 to 0.96, indicating good test-retest reliability. The machine learning methods had lower sensitivity than mean clinical ratings (Figure. 1).

    Conclusions: The presented methodology was able to assess motor symptoms in PD well, comparable to movement disorder experts. The leg agility test did not reflect treatment related changes.

  • 41.
    Aghanavesi, Somayeh
    et al.
    Computer Engineering, School of Technology and Business Studies, Dalarna University, Borlänge, Sweden.
    Filip, Bergquist
    Dept. of Pharmacology, University of Gothenburg, Gothenbrug, Sweden.
    Nyholm, Dag
    Dept. of Neuroscience, Neurology, Uppsala University, Uppsala, Sweden.
    Senek, Marina
    Dept. of Neuroscience, Neurology, Uppsala University, Uppsala, Sweden.
    Memedi, Mevludin
    Örebro University, Örebro University School of Business.
    Feasibility of a multi-sensor data fusion method for assessment of Parkinson’s disease motor symptoms2018Conference paper (Other academic)
    Abstract [en]

    Title: Feasibility of a multi-sensor data fusion method for assessment of Parkinson’s disease motor symptoms

    Objective: To assess the feasibility of measuring Parkinson’s disease (PD) motor symptoms with a multi-sensor data fusion method. More specifically, the aim is to assess validity, reliability and sensitivity to treatment of the methods.

    Background: Data from 19 advanced PD patients (Gender: 14 males and 5 females, mean age: 71.4, mean years with PD: 9.7, mean years with levodopa: 9.5) were collected in a single center, open label, single dose clinical trial in Sweden [1].

    Methods: The patients performed leg agility and 2-5 meter straight walking tests while wearing motion sensors on their limbs. They performed the tests at baseline, at the time they received the morning dose, and at pre-specified time points until the medication wore off. While performing the tests the patients were video recorded. The videos were observed by three movement disorder specialists who rated the symptoms using a treatment response scale (TRS), ranging from -3 (very off) to 3 (very dyskinetic). The sensor data consisted of lower limb data during leg agility, upper limb data during walking, and lower limb data during walking. Time series analysis was performed on the raw sensor data extracted from 17 patients to derive a set of quantitative measures, which were then used during machine learning to be mapped to mean ratings of the three raters on the TRS scale. Combinations of data were tested during the machine learning procedure.

    Results: Using data from both tests, the Support Vector Machines (SVM) could predict the motor states of the patients on the TRS scale with a good agreement in relation to the mean ratings of the three raters (correlation coefficient = 0.92, root mean square error = 0.42, p<0.001). Additionally, there was good test-retest reliability of the SVM scores during baseline and second tests with intraclass-correlation coefficient of 0.84. Sensitivity to treatment for SVM was good (Figure 1), indicating its ability to detect changes in motor symptoms. The upper limb data during walking was more informative than lower limb data during walking since SVMs had higher correlation coefficient to mean ratings.  

    Conclusions: The methodology demonstrates good validity, reliability, and sensitivity to treatment. This indicates that it could be useful for individualized optimization of treatments among PD patients, leading to an improvement in health-related quality of life.

  • 42.
    Aghanavesi, Somayeh
    et al.
    School of Technology and Business Studies, Computer Engineering, Dalarna University, Falun, Sweden.
    Memedi, Mevludin
    Örebro University, Örebro University School of Business.
    Dougherty, Mark
    School of Technology and Business Studies, Computer Engineering, Dalarna University, Falun, Sweden.
    Nyholm, Dag
    Department of Neuroscience, Neurology, Uppsala University, Uppsala, Sweden.
    Westin, Jerker
    School of Technology and Business Studies, Computer Engineering, Dalarna University, Falun, Sweden.
    Verification of a Method for Measuring Parkinson’s Disease Related Temporal Irregularity in Spiral Drawings2017In: Sensors, ISSN 1424-8220, E-ISSN 1424-8220, Vol. 17, no 10, article id 2341Article in journal (Refereed)
    Abstract [en]

    Parkinson’s disease (PD) is a progressive movement disorder caused by the death of dopamine-producing cells in the midbrain. There is a need for frequent symptom assessment, since the treatment needs to be individualized as the disease progresses. The aim of this paper was to verify and further investigate the clinimetric properties of an entropy-based method for measuring PD-related upper limb temporal irregularities during spiral drawing tasks. More specifically, properties of a temporal irregularity score (TIS) for patients at different stages of PD, and medication time points were investigated. Nineteen PD patients and 22 healthy controls performed repeated spiral drawing tasks on a smartphone. Patients performed the tests before a single levodopa dose and at specific time intervals after the dose was given. Three movement disorder specialists rated videos of the patients based on the unified PD rating scale (UPDRS) and the Dyskinesia scale. Differences in mean TIS between the groups of patients and healthy subjects were assessed. Test-retest reliability of the TIS was measured. The ability of TIS to detect changes from baseline (before medication) to later time points was investigated. Correlations between TIS and clinical rating scores were assessed. The mean TIS was significantly different between healthy subjects and patients in advanced groups (p-value = 0.02). Test-retest reliability of TIS was good with Intra-class Correlation Coefficient of 0.81. When assessing changes in relation to treatment, TIS contained some information to capture changes from Off to On and wearing off effects. However, the correlations between TIS and clinical scores (UPDRS and Dyskinesia) were weak. TIS was able to differentiate spiral drawings drawn by patients in an advanced stage from those drawn by healthy subjects, and TIS had good test-retest reliability. TIS was somewhat responsive to single-dose levodopa treatment. Since TIS is an upper limb high-frequency-based measure, it cannot be detected during clinical assessment.

  • 43.
    Aghanavesi, Somayeh
    et al.
    Computer Engineering, School of Technology and Business Studies, Dalarna University, Borlänge, Sweden.
    Memedi, Mevludin
    Örebro University, Örebro University School of Business.
    Westin, Jerker
    Computer Engineering, School of Technology and Business Studies, Dalarna University, Borlänge, Sweden.
    Measuring temporal irregularity in spiral drawings of patients with Parkinson’s disease2017In: Abstracts of the 21st International Congress of Parkinson's Disease and Movement Disorders, John Wiley & Sons, 2017, Vol. 32, p. s252-s252, article id 654Conference paper (Other (popular science, discussion, etc.))
    Abstract [en]

    Objective: The aim of this work is to evaluate clinimetric properties of a method for measuring Parkinson’s disease (PD) upper limb temporal irregularities during spiral drawing tasks.

    Background: Basal ganglia fluctuations of PD patients are associated with motor symptoms and relating them to objective sensor-based measures may facilitate the assessment of temporal irregularities, which could be difficult to be assessed visually. The present study investigated the upper limb temporal irregularity of patients at different stages of PD and medication time points.

    Methods: Nineteen PD patients and 22 healthy controls performed repeated spiral drawing tasks on a smartphone. Patients performed the tests before a single levodopa dose and at specific time intervals after the dose was given. Three movement disorder specialists rated the videos of patients' performance according to six items of UPDRS-III, dyskinesia (Dys), and Treatment Response Scale (TRS). A temporal irregularity score (TIS) was developed using approximate entropy (ApEn) method. Differences in mean TIS between two groups of patients and healthy subjects, and also across four subject groups: early, intermediate, advanced patients and, healthy subjects were assessed. The relative ability of TIS to detect changes from baseline (no medication) to later time points when patients were on medication was assessed. Correlations between TIS and clinical rating scales were assessed by Pearson correlation coefficients and test-retest reliability of TIS was measured by intra-class correlation coefficients (ICC).

    Results: The mean TIS was significantly different between healthy subjects and patients (P<0.0001). When assessing the changes in relation to treatment, clinical-based scores (TRS and Dys) had better responsiveness than TIS. However, the TIS was able to capture changes from Off to On, and the wearing off effects. Correlations between TIS and clinical scales were low indicating poor validity. Test-retest reliability correlation coefficient of the mean TIS was good (ICC=0.67).

    Conclusions: Our study found that TIS was able to differentiate spiral drawings drawn by patients from those drawn by healthy subjects. In addition, TIS could capture changes throughout the levodopa cycle.TIS was weakly correlated to clinical ratings indicating that TIS measures high frequency upper limb temporal irregularities that could be difficult to be detected during clinical observations.

  • 44.
    Aghanavesi, Somayeh
    et al.
    Computer Engineering, School of Technology and Business Studies, Dalarna University, Falun, Sweden.
    Nyholm, Dag
    Dept. of Neuroscience, Neurology, Uppsala University, Uppsala, Sweden.
    Senek, Marina
    Dept. of Neuroscience, Neurology, Uppsala University, Uppsala, Sweden.
    Bergquist, Filip
    Dept. of Pharmacology, University of Gothenburg, Gothenburg, Sweden.
    Memedi, Mevludin
    Örebro University, Örebro University School of Business. Computer Engineering, School of Technology and Business Studies, Dalarna University, Falun, Sweden.
    A smartphone-based system to quantify dexterity in Parkinson's disease patients2017In: Informatics in Medicine Unlocked, ISSN 2352-9148Article in journal (Refereed)
    Abstract [en]

    Objectives

    The aim of this paper is to investigate whether a smartphone-based system can be used to quantify dexterity in Parkinson's disease (PD). More specifically, the aim was to develop data-driven methods to quantify and characterize dexterity in PD.

    Methods

    Nineteen advanced PD patients and 22 healthy controls participated in a clinical trial in Uppsala, Sweden. The subjects were asked to perform tapping and spiral drawing tests using a smartphone. Patients performed the tests before, and at pre-specified time points after they received 150% of their usual levodopa morning dose. Patients were video recorded and their motor symptoms were assessed by three movement disorder specialists using three Unified PD Rating Scale (UPDRS) motor items from part III, the dyskinesia scoring and the treatment response scale (TRS). The raw tapping and spiral data were processed and analyzed with time series analysis techniques to extract 37 spatiotemporal features. For each of the five scales, separate machine learning models were built and tested by using principal components of the features as predictors and mean ratings of the three specialists as target variables.

    Results

    There were weak to moderate correlations between smartphone-based scores and mean ratings of UPDRS item #23 (0.52; finger tapping), UPDRS #25 (0.47; rapid alternating movements of hands), UPDRS #31 (0.57; body bradykinesia and hypokinesia), sum of the three UPDRS items (0.46), dyskinesia (0.64), and TRS (0.59). When assessing the test-retest reliability of the scores it was found that, in general, the clinical scores had better test-retest reliability than the smartphone-based scores. Only the smartphone-based predicted scores on the TRS and dyskinesia scales had good repeatability with intra-class correlation coefficients of 0.51 and 0.84, respectively. Clinician-based scores had higher effect sizes than smartphone-based scores indicating a better responsiveness in detecting changes in relation to treatment interventions. However, the first principal component of the 37 features was able to capture changes throughout the levodopa cycle and had trends similar to the clinical TRS and dyskinesia scales. Smartphone-based scores differed significantly between patients and healthy controls.

    Conclusions

    Quantifying PD motor symptoms via instrumented, dexterity tests employed in a smartphone is feasible and data from such tests can also be used for measuring treatment-related changes in patients.

  • 45.
    Agneson, Henry
    et al.
    Örebro University, Örebro University School of Business.
    Lundberg, Sara
    Örebro University, Örebro University School of Business.
    Von Bothmer, Henrik
    Örebro University, Örebro University School of Business.
    Hållbarhetsredovisning i svenska företag - En branschspecifik studie2016Independent thesis Basic level (degree of Bachelor), 10 credits / 15 HE creditsStudent thesis
  • 46.
    Agélii Genlott, Annika
    et al.
    Örebro University, Örebro University School of Business.
    Grönlund, Åke
    Örebro University, Örebro University School of Business.
    Att lära sig läsa och skriva - i nutid och för framtid2014In: Interaktiva medier och lärandemiljöer / [ed] Elza Dunkels; Simon Lindgren, Malmö: Gleerups Utbildning AB, 2014, 1, p. 155-166Chapter in book (Refereed)
  • 47.
    Agélii Genlott, Annika
    et al.
    Örebro University, Örebro University School of Business.
    Grönlund, Åke
    Örebro University, Örebro University School of Business.
    Closing the gaps: Improving literacy and mathematics by ict-enhanced collaboration2016In: Computers and education, ISSN 0360-1315, E-ISSN 1873-782X, Vol. 99, p. 68-80Article in journal (Refereed)
    Abstract [en]

    Literacy and mathematics are necessary skills that for different reasons unfortunately not everybody acquires sufficiently. In OECD countries there is also a gender gap; boys lag behind girls in literacy but often outperform girls in mathematics (OECD, 2012). ICT (Information and communication technologies) may contribute useful tools to address both these problems but in order to effectively create better educational conditions there is yet a need to develop effective methods that combine ICT with key factors for learning. This research contributes to this by measuring effects of the “Write to Learn” (WTL) method. WTL lets children from 1st grade use several ICT tools to write texts and subsequently discuss and refine them together with classmates and teachers using digital real-time formative feedback and assessment. The central learning factor addressed, in mathematics as well as in literacy, is the written communication allowing the learners to interact with peers and teachers. WTL draws on methods from socio-cultural theory, including continuous social interaction and written real-time formative feedback among peers, using shared electronic forums for collaboration, thereby providing social meaning and increased learning of literacy and mathematics, among both boys and girls.

    The study uses quantitative methods and two control groups, one using traditional method (no ICT) and one using technology individually (without integrated social interaction and formative feedback), to compare results from 502 students in grade 3 national tests in mathematics and literacy. WTL yields by far best results; higher average score both in literacy and mathematics, smaller gender gap, and significantly better results for the under-achievers. The ITU method performs worst, which shows that ICT use must be well integrated into the pedagogy to be useful.

  • 48.
    Ahdrian, Micaela
    et al.
    Örebro University, Örebro University School of Business.
    Nilsson, Annika
    Örebro University, Örebro University School of Business.
    Marknadskanalsystemets evolution på den svenska klädmarknaden 1991-2012: En dominant design-analys2013Independent thesis Advanced level (degree of Master (One Year)), 20 credits / 30 HE creditsStudent thesis
  • 49.
    Ahlberg, Annéa
    et al.
    Örebro University, Örebro University School of Business.
    Andersson, Sarah
    Örebro University, Örebro University School of Business.
    Intentioner till hållbart konsumentbeteende: Med fokus på hållbara fonder2015Independent thesis Advanced level (degree of Master (Two Years)), 20 credits / 30 HE creditsStudent thesis
  • 50.
    Ahlberg, Joakim
    Örebro University, Örebro University School of Business.
    Analysis of discrete multi-unit, common value auctions: a study of three sealed-bid mechanismsManuscript (preprint) (Other academic)
    Abstract [en]

    This paper proposes a discrete bidding model for both quantities and pricing. It has a two-unit demand environment where subjects bid for contracts with an unknown redemption value, common to all bidders. Prior to bidding, the bidders receive private signals of information on the (common) value. The value and the signals are drawn from a known discrete affiliated joint distribution. The relevant task for the paper is to compare the equilibrium strategies and the seller’s revenue of three auction formats. We find that, of the three auctionformats below with two players, the discriminatory auction always gives the largest revenue to the seller; both the uniform and the Vickrey auction have zero revenue equilibrium strategies that put them further down in the revenue ranking. In equilibrium, bidders bid the same amount on both items in the discriminatory auction; a phenomenon not noted in either of the other auction formats.

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