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  • 1.
    Jerlström, Tomas
    et al.
    Department of Urology, University Hospital, Örebro, Sweden.
    Gardmark, Truls
    Dept Surg & Urol, Danderyd Hosp, Danderyd, Sweden.
    Carringer, Malcolm
    Örebro University Hospital. Department of Urology, Örebro University Hospital, Örebro, Sweden.
    Holmang, Sten
    Dept Urol, Sahlgrens Univ Hosp, Gothenburg, Sweden.
    Liedberg, Fredrik
    Dept Urol, Skåne Univ Hosp, Malmö, Sweden.
    Hosseini, Abolfazl
    Dept Mol Med & Surg, Urol Sect, Karolinska Inst, Stockholm, Sweden.
    Malmström, Per-Uno
    Dept Surg Sci, Uppsala Univ, Uppsala, Sweden.
    Ljungberg, Börje
    Dept Surg & Perioperat Sci Urol & Androl, Norrlands Univ Hosp, Umeå, Sweden.
    Hagberg, Oskar
    Reg Canc Ctr South, Lund, Sweden.
    Jahnson, Staffan
    Dept Clin & Expt Med, Div Urol, Linköping Univ Hosp, Linköping, Sweden.
    Urinary bladder cancer treated with radical cystectomy: Perioperative parameters and early complications prospectively registered in a national population-based database2014In: Scandinavian journal of urology, ISSN 2168-1805, E-ISSN 2168-1813, Vol. 48, no 4, p. 334-340Article in journal (Refereed)
    Abstract [en]

    Objective: Cystectomy combined with pelvic lymph-node dissection and urinary diversion entails high morbidity and mortality. Improvements are needed, and a first step is to collect information on the current situation. In 2011, this group took the initiative to start a population-based database in Sweden (population 9.5 million in 2011) with prospective registration of patients and complications until 90 days after cystectomy. This article reports findings from the first year of registration.

    Material and methods: Participation was voluntary, and data were reported by local urologists or research nurses. Perioperative parameters and early complications classified according to the modified Clavien system were registered, and selected variables of possible importance for complications were analysed by univariate and multivariate logistic regression.

    Results: During 2011, 285 (65%) of 435 cystectomies performed in Sweden were registered in the database, the majority reported by the seven academic centres. Median blood loss was 1000 ml, operating time 318 min, and length of hospital stay 15 days. Any complications were registered for 103 patients (36%). Clavien grades 1-2 and 3-5 were noted in 19% and 15%, respectively. Thirty-seven patients (13%) were reoperated on at least once. In logistic regression analysis elevated risk of complications was significantly associated with operating time exceeding 318 min in both univariate and multivariate analysis, and with age 76-89 years only in multivariate analysis.

    Conclusions: It was feasible to start a national population-based registry of radical cystectomies for bladder cancer. The evaluation of the first year shows an increased risk of complications in patients with longer operating time and higher age. The results agree with some previously published series but should be interpreted with caution considering the relatively low coverage, which is expected to be higher in the future.

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