oru.sePublications
Change search
Refine search result
1 - 4 of 4
CiteExportLink to result list
Permanent link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Rows per page
  • 5
  • 10
  • 20
  • 50
  • 100
  • 250
Sort
  • Standard (Relevance)
  • Author A-Ö
  • Author Ö-A
  • Title A-Ö
  • Title Ö-A
  • Publication type A-Ö
  • Publication type Ö-A
  • Issued (Oldest first)
  • Issued (Newest first)
  • Created (Oldest first)
  • Created (Newest first)
  • Last updated (Oldest first)
  • Last updated (Newest first)
  • Disputation date (earliest first)
  • Disputation date (latest first)
  • Standard (Relevance)
  • Author A-Ö
  • Author Ö-A
  • Title A-Ö
  • Title Ö-A
  • Publication type A-Ö
  • Publication type Ö-A
  • Issued (Oldest first)
  • Issued (Newest first)
  • Created (Oldest first)
  • Created (Newest first)
  • Last updated (Oldest first)
  • Last updated (Newest first)
  • Disputation date (earliest first)
  • Disputation date (latest first)
Select
The maximal number of hits you can export is 250. When you want to export more records please use the Create feeds function.
  • 1.
    Ganda Mall, John-Peter
    et al.
    Örebro University, School of Medical Sciences.
    Fart, Frida
    Örebro University, School of Medical Sciences.
    Sabet, Julia
    Örebro University, School of Medical Sciences.
    Lindqvist, Carl-Mårten
    Örebro University, School of Medical Sciences.
    Keita, Åsa V.
    Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden.
    Brummer, Robert J.
    Örebro University, School of Medical Sciences.
    Schoultz, Ida
    Örebro University, School of Medical Sciences.
    Effects of dietary fibres on indomethacin-induced intestinal permeability in elderly: A randomised placebo controlled parallel clinical trialManuscript (preprint) (Other academic)
  • 2.
    Hiyoshi, Ayako
    et al.
    Örebro University, School of Medical Sciences.
    Sabet, Julia A.
    Örebro University, School of Medical Sciences.
    Sjöqvist, Hugo
    Örebro University, Örebro University School of Business.
    Melinder, Carren
    Örebro University, School of Medical Sciences.
    Brummer, Robert Jan
    Örebro University, School of Medical Sciences.
    Montgomery, Scott
    Örebro University, School of Medical Sciences. Clinical Epidemiology Unit, Karolinska Institutet, Stockholm, Sweden; Department of Epidemiology and Public Health, University College London, London, UK .
    Precursors in adolescence of adult-onset bipolar disorder2017In: Journal of Affective Disorders, ISSN 0165-0327, E-ISSN 1573-2517, Vol. 218, p. 353-358Article in journal (Refereed)
    Abstract [en]

    Background: Although the estimated contribution of genetic factors is high in bipolar disorder, environmental factors may also play a role. This Swedish register-based cohort study of men examined if physical and psychological characteristics in late adolescence, including factors previously linked with bipolar disorder (body mass index, asthma and allergy), are associated with subsequent bipolar disorder in adulthood. Unipolar depression and anxiety are analysed as additional outcomes to identify bipolar disorder-specific associations.

    Methods: A total of 213,693 men born between 1952 and 1956, who participated in compulsory military conscription assessments in late adolescence were followed up to 2009, excluding men with any psychiatric diagnoses at baseline. Cox regression estimated risk of bipolar disorder, depression and anxiety in adulthood associated with body mass index, asthma, allergy, muscular strength stress resilience and cognitive function in adolescence.

    Results: BMI, asthma and allergy were not associated with bipolar disorder. Higher grip strength, cognitive function and stress resilience were associated with a reduced risk of bipolar disorder and the other disease outcomes.

    Limitations: The sample consisted only of men; even though the characteristics in adolescence pre-dated disease onset, they may have been the consequence of prodromal disease.

    Conclusions: Associations with body mass index and asthma found by previous studies may be consequences of bipolar disorder or its treatment rather than risk factors. Inverse associations with all the outcome diagnoses for stress resilience, muscular strength and cognitive function may reflect general risks for these psychiatric disorders or intermediary factors.

  • 3.
    Sabet, Julia A.
    et al.
    Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, United States of America; Friedman School of Nutrition Science and Policy, Tufts University, Boston, United States of America .
    Park, Lara K.
    Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, United States of America; Friedman School of Nutrition Science and Policy, Tufts University, Boston, United States of America.
    Iyer, Lakshmanan K.
    Tufts Center for Neuroscience Research, Neuroscience Department, Tufts University School of Medicine, Boston, United States of America; Molecular Cardiology Research Institute, Tufts Medical Center, Boston, United States of America .
    Tai, Albert K.
    Tufts University School of Medicine, Tufts University Core Facility, Boston, United States of America.
    Koh, Gar Yee
    Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, United States of America .
    Pfalzer, Anna C.
    Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, United States of America; Friedman School of Nutrition Science and Policy, Tufts University, Boston, United States of America .
    Parnell, Laurence D.
    Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, United States of America.
    Mason, Joel B.
    Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, United States of America; Friedman School of Nutrition Science and Policy, Tufts University, Boston, United States of America .
    Liu, Zhenhua
    Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, United States of America; Friedman School of Nutrition Science and Policy, Tufts University, Boston, United States of America .
    Byun, Alexander J.
    Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, United States of America.
    Crott, Jimmy W.
    Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Bostons, United States of America; Friedman School of Nutrition Science and Policy, Tufts University, Boston, United States of America .
    Correction: Paternal B Vitamin Intake Is a Determinant of Growth, Hepatic Lipid Metabolism and Intestinal Tumor Volume in Female Apc1638N Mouse Offspring2016In: PLoS ONE, ISSN 1932-6203, E-ISSN 1932-6203, Vol. 11, no 4, article id e0154979Article in journal (Refereed)
  • 4.
    Sabet, Julia A.
    et al.
    Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, United States of America; Friedman School of Nutrition Science and Policy, Tufts University, Boston, United States of America.
    Park, Lara K.
    Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, United States of America; Friedman School of Nutrition Science and Policy, Tufts University, Boston, United States of America.
    Iyer, Lakshmanan K.
    Tufts Center for Neuroscience Research, Neuroscience Department, Tufts University School of Medicine, Boston, United States of America; Molecular Cardiology Research Institute, Tufts Medical Center, Boston, United States of America.
    Tai, Albert K.
    Tufts Center for Neuroscience Research, Neuroscience Department, Tufts University School of Medicine, Boston, United States of America, Molecular Cardiology Research Institute, Tufts Medical Center, Boston, United States of America.
    Koh, Gar Yee
    Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, United States of America.
    Pfalzer, Anna C.
    Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, United States of America; Friedman School of Nutrition Science and Policy ,Tufts University, Boston, United States of America.
    Parnell, Laurence D.
    Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, United States of America.
    Mason, Joel B.
    Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, United States of America; Friedman School of Nutrition Science and Policy, Tufts University, Boston, United States of America.
    Liu, Zhenhua
    Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, United States of America; School of Public Health and Health Sciences, UMass Amherst, Amherst, United States of America .
    Byun, Alexander J.
    Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, United States of America.
    Crott, Jimmy W.
    Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, United States of America; Friedman School of Nutrition Science and Policy, Tufts University, Boston, United States of America.
    Paternal B Vitamin Intake Is a Determinant of Growth, Hepatic Lipid Metabolism and Intestinal Tumor Volume in Female Apc1638N Mouse Offspring2016In: PLoS ONE, ISSN 1932-6203, E-ISSN 1932-6203, Vol. 11, no 3, article id e0151579Article in journal (Refereed)
    Abstract [en]

    BACKGROUND: The importance of maternal nutrition to offspring health and risk of disease is well established. Emerging evidence suggests paternal diet may affect offspring health as well.

    OBJECTIVE: In the current study we sought to determine whether modulating pre-conception paternal B vitamin intake alters intestinal tumor formation in offspring. Additionally, we sought to identify potential mechanisms for the observed weight differential among offspring by profiling hepatic gene expression and lipid content.

    METHODS: Male Apc1638N mice (prone to intestinal tumor formation) were fed diets containing replete (control, CTRL), mildly deficient (DEF), or supplemental (SUPP) quantities of vitamins B2, B6, B12, and folate for 8 weeks before mating with control-fed wild type females. Wild type offspring were euthanized at weaning and hepatic gene expression profiled. Apc1638N offspring were fed a replete diet and euthanized at 28 weeks of age to assess tumor burden.

    RESULTS: No differences in intestinal tumor incidence or burden were found between male Apc1638N offspring of different paternal diet groups. Although in female Apc1638N offspring there were no differences in tumor incidence or multiplicity, a stepwise increase in tumor volume with increasing paternal B vitamin intake was observed. Interestingly, female offspring of SUPP and DEF fathers had a significantly lower body weight than those of CTRL fed fathers. Moreover, hepatic trigylcerides and cholesterol were elevated 3-fold in adult female offspring of SUPP fathers. Weanling offspring of the same fathers displayed altered expression of several key lipid-metabolism genes. Hundreds of differentially methylated regions were identified in the paternal sperm in response to DEF and SUPP diets. Aside from a few genes including Igf2, there was a striking lack of overlap between these genes differentially methylated in sperm and differentially expressed in offspring.

    CONCLUSIONS: In this animal model, modulation of paternal B vitamin intake prior to mating alters offspring weight gain, lipid metabolism and tumor growth in a sex-specific fashion. These results highlight the need to better define how paternal nutrition affects the health of offspring.

1 - 4 of 4
CiteExportLink to result list
Permanent link
Cite
Citation style
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf