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  • 151.
    Abrahamsson, Pär
    et al.
    Örebro universitet, Institutionen för ekonomi, statistik och informatik.
    Eklund, Alexander
    Örebro universitet, Institutionen för ekonomi, statistik och informatik.
    Nyföretagarservice: Rådgivningen och utbildningens roll vid nyföretagande2006Independent thesis Advanced level (degree of Master (One Year)), 10 poäng / 15 hpOppgave
  • 152.
    Abrahamsson, T. R.
    et al.
    Dept Clin & Expt Med, Div Pediat, Linköping Univ, Linköping, Sweden.
    Jakobsson, H. E.
    Dept Microbiol Tumor & Cell Biol, Karolinska Inst, Stockholm, Sweden.
    Andersson, A. F.
    Sch Biotechnol, Div Gene Technol, Sci Life Lab, Royal Inst Technol (KTH ), Stockholm, Sweden.
    Björkstén, Bengt
    Örebro universitet, Institutionen för hälsovetenskap och medicin.
    Engstrand, L.
    Dept Microbiol Tumor & Cell Biol, Karolinska Inst, Stockholm, Sweden; Div Gene Technol, Sci Life Lab, KTH Royal Inst Technol, Sch Biotechnol, Stockholm, Sweden.
    Jenmalm, M. C.
    Dept Clin & Expt Med, Div Pediat, Linköping Univ, Linköping, Sweden; Dept Clin & Expt Med, Div Clin Immunol, Unit Autoimmun & Immune Regulat, Linköping Univ, Linköping, Sweden.
    Low gut microbiota diversity in early infancy precedes asthma at school age2014Inngår i: Clinical and Experimental Allergy, ISSN 0954-7894, E-ISSN 1365-2222, Vol. 44, nr 6, s. 842-850Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Background Low total diversity of the gut microbiota during the first year of life is associated with allergic diseases in infancy, but little is known how early microbial diversity is related to allergic disease later in school age. Objective To assess microbial diversity and characterize the dominant bacteria in stool during the first year of life in relation to the prevalence of different allergic diseases in school age, such as asthma, allergic rhinoconjunctivitis (ARC) and eczema. Methods The microbial diversity and composition was analysed with barcoded 16S rDNA 454 pyrosequencing in stool samples at 1week, 1month and 12months of age in 47 infants which were subsequently assessed for allergic disease and skin prick test reactivity at 7years of age (ClinicalTrials.gov ID NCT01285830). Results Children developing asthma (n=8) had a lower diversity of the total microbiota than non-asthmatic children at 1week (P=0.04) and 1month (P=0.003) of age, whereas allergic rhinoconjunctivitis (n=13), eczema (n=12) and positive skin prick reactivity (n=14) at 7years of age did not associate with the gut microbiota diversity. Neither was asthma associated with the microbiota composition later in infancy (at 12months). Children having IgE-associated eczema in infancy and subsequently developing asthma had lower microbial diversity than those that did not. There were no significant differences, however, in relative abundance of bacterial phyla and genera between children with or without allergic disease. Conclusion and Clinical Relevance Low total diversity of the gut microbiota during the first month of life was associated with asthma but not ARC in children at 7years of age. Measures affecting microbial colonization of the infant during the first month of life may impact asthma development in childhood.

  • 153.
    Abrahamsson, Thomas R.
    et al.
    Dept Clin & Expt Med, Div Pediat, Linköping University, Linköping, Sweden.
    Jakobsson, Hedvig E.
    Dept Microbiol Tumor & Cell Biol, Karolinska Institute, Stockholm, Sweden.
    Andersson, Anders F.
    Sch Biotechnol, Sci Life Lab, KTH Royal Inst Technol, Stockholm, Sweden.
    Björksten, Bengt
    Örebro universitet, Institutionen för hälsovetenskap och medicin. Inst Environm Med, Karolinska Institute, Stockholm, Sweden.
    Engstrand, Lars
    Sch Biotechnol, Sci Life Lab, KTH Royal Inst Technol, Stockholm, Sweden.
    Jenmalm, Maria C.
    Dept Clin & Expt Med, Div Pediat, Linköping University, Linköping, Sweden.; Unit Autoimmun & Immune Regulat, Dept Clin & Expt Med, Div Clin Immunol, Linköping University, Linköping, Sweden.
    Gut microbiota diversity and atopic disease: Does breast-feeding play a role? Reply2013Inngår i: Journal of Allergy and Clinical Immunology, ISSN 0091-6749, E-ISSN 1097-6825, Vol. 131, nr 1, s. 248-249Artikkel i tidsskrift (Fagfellevurdert)
  • 154.
    Abrahamsson, Thomas R.
    et al.
    Department of Clinical and Experimental Medicine, Division of Pediatrics, Linköping University, Linköping, Sweden.
    Jakobsson, Hedvig E.
    Department of Preparedness, Swedish Institute for Communicable Disease Control, Solna, Sweden; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.
    Andersson, Anders F.
    Science for Life Laboratory, School of Biotechnology, KTH Royal Institute of Technology, Stockholm, Sweden .
    Björkstén, Bengt
    Örebro universitet, Institutionen för hälsovetenskap och medicin. Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden; .
    Engstrand, Lars
    Department of Preparedness, Swedish Institute for Communicable Disease Control, Solna, Sweden; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.
    Jenmalm, Maria C.
    Department of Clinical and Experimental Medicine, Division of Pediatrics, Linköping University, Linköping, Sweden; Department of Clinical and Experimental Medicine, Unit of Autoimmunity and Immune Regulation, Linköping University, Linköping, Sweden.
    Low diversity of the gut microbiota in infants with atopic eczema2012Inngår i: Journal of Allergy and Clinical Immunology, ISSN 0091-6749, E-ISSN 1097-6825, Vol. 129, nr 2, s. 434-440.e2Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Background: It is debated whether a low total diversity of the gut microbiota in early childhood is more important than an altered prevalence of particular bacterial species for the increasing incidence of allergic disease. The advent of powerful, cultivation-free molecular methods makes it possible to characterize the total microbiome down to the genus level in large cohorts.

    Objective: We sought to assess microbial diversity and characterize the dominant bacteria in stool during the first year of life in relation to atopic eczema development.

    Methods: Microbial diversity and composition were analyzed with barcoded 16S rDNA 454-pyrosequencing in stool samples at 1 week, 1 month, and 12 months of age in 20 infants with IgE-associated eczema and 20 infants without any allergic manifestation until 2 years of age (ClinicalTrials.gov ID NCT01285830).

    Results: Infants with IgE-associated eczema had a lower diversity of the total microbiota at 1 month (P = .004) and a lower diversity of the bacterial phylum Bacteroidetes and the genus Bacteroides at 1 month (P = .02 and P = .01) and the phylum Proteobacteria at 12 months of age (P = .02). The microbiota was less uniform at 1 month than at 12 months of age, with a high interindividual variability. At 12 months, when the microbiota had stabilized, Proteobacteria, comprising gram-negative organisms, were more abundant in infants without allergic manifestation (Empirical Analysis of Digital Gene Expression in R [edgeR] test: P = .008, q = 0.02).

    Conclusion: Low intestinal microbial diversity during the first month of life was associated with subsequent atopic eczema.

  • 155. Abrahamsson, Thomas R.
    et al.
    Jakobsson, Ted
    Björkstén, Bengt
    Örebro universitet, Institutionen för hälsovetenskap och medicin.
    Oldaeus, Göran
    Jenmalm, Maria C.
    No effect of probiotics on respiratory allergies: a seven-year follow-up of a randomized controlled trial in infancy2013Inngår i: Pediatric Allergy and Immunology, ISSN 0905-6157, E-ISSN 1399-3038, Vol. 24, nr 6, s. 556-561Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Background: Supplementation with the probioticLactobacillus reuteri reduced the incidence of IgE-associated allergic disease in infancy. This treatment might therefore also reduce the risk of asthma and allergic rhinoconjunctivitis in school age.

    Objective: To evaluate whether perinatal and infant supplementation withL.reuteri reduced the prevalence of respiratory allergic disease in school age and to explore whether this supplementation was associated with any long-term side effects.

    Methods: A randomized, placebo-controlled trial with oral supplementation withL.reuteriATCC 55730 (1x10(8)CFU) during the last month of gestation and through the first year of life comprising 232 families with allergic disease, of whom 184 completed a 7-yr follow-up. The primary outcomes at 7yr of age were allergic disease and skin prick test reactivity (ClinicalTrials.govID NCT01285830).

    Results: The prevalence of asthma (15% in the probiotic vs. 16% in placebo group), allergic rhinoconjunctivitis (27% vs. 20%), eczema (21% vs. 19%) and skin prick test reactivity (29% vs. 26%) was similar in the probiotic and placebo group. Growth indices and gastrointestinal symptoms were similar in the two groups. No severe adverse events were reported.

    Conclusion: The effect ofL.reuteri on sensitization andIgE-associated eczema in infancy did not lead to a lower prevalence of respiratory allergic disease in school age. Thus, the effect ofL.reuteri on the immune system seems to be transient. Administration ofL.reuteri during the last weeks of gestation and in infancy was not associated with any long-term side effects.

  • 156.
    Abrahamsson, Valensia
    et al.
    Örebro universitet, Handelshögskolan vid Örebro Universitet.
    Halef, Charbel
    Örebro universitet, Handelshögskolan vid Örebro Universitet.
    Anställdas motivation inom tillverkningsindustrin: En kvalitativ fallstudie med utgångspunkt i förväntansteorin 2018Independent thesis Basic level (degree of Bachelor), 10 poäng / 15 hpOppgave
  • 157.
    Abramsson, Alexander
    et al.
    Örebro universitet, Handelshögskolan vid Örebro Universitet.
    Happonen, Anna
    Örebro universitet, Handelshögskolan vid Örebro Universitet.
    Malmsten, Dennis
    Örebro universitet, Handelshögskolan vid Örebro Universitet.
    Aktieindexobligationer: En studie om struktur och prissättning av produkter på den svenska marknaden2013Independent thesis Basic level (degree of Bachelor), 10 poäng / 15 hpOppgave
  • 158.
    Abramsson, Heidi
    et al.
    Örebro universitet, Akademin för juridik, psykologi och socialt arbete.
    Hummerhielm, Michaela
    Örebro universitet, Akademin för juridik, psykologi och socialt arbete.
    Barn till missbrukande föräldrar: En studie om påverkan och en stödgruppsverksamhet2010Independent thesis Basic level (degree of Bachelor), 10 poäng / 15 hpOppgave
  • 159.
    Abrego, Lisandro
    et al.
    International Monetary Fund, Washington DC, USA.
    Österholm, Pär
    National Institute of Economic Research, Stockholm, Sweden.
    External Linkages and Economic Growth in Colombia: Insights from a Bayesian VAR Model2010Inngår i: The World Economy, ISSN 0378-5920, E-ISSN 1467-9701, Vol. 33, nr 12, s. 1788-1810Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    This paper investigates the sensitivity of Colombian GDP growth to the surrounding macroeconomic environment. We estimate a Bayesian VAR model with informative steady-state priors for the Colombian economy using quarterly data from 1995 to 2007. A variance decomposition shows that world GDP growth and government spending are the most important factors, explaining roughly 17 and 16 per cent of the variance in Colombian GDP growth respectively. The model, which is shown to forecast well out-of-sample, can also be used to analyse alternative scenarios. Generating both endogenous and conditional forecasts, we show that the impact on Colombian GDP growth of a substantial downturn in world GDP growth would be non-negligible but that the decline still would be mild by historical standards.

  • 160.
    Abrikossova, Natalia
    et al.
    Division of Molecular Surface Physics and Nanoscience, Department of Physics, Chemistry and Biology, Linköping University, Linköping, Sweden .
    Skoglund, Caroline
    Division of Molecular Surface Physics and Nanoscience, Department of Physics, Chemistry and Biology, Linköping University, Linköping, Sweden; Division of Clinical Medicine, Department of Biomedicine, Örebro University, Örebro, Sweden.
    Ahrén, Maria
    Division of Molecular Surface Physics and Nanoscience, Department of Physics, Chemistry and Biology, Linköping University, Linköping, Sweden.
    Bengtsson, Torbjörn
    Örebro universitet, Institutionen för hälsovetenskap och medicin. Division of Clinical Medicine, Department of Biomedicine, School of Health and Medical Sciences, Örebro University, Örebro, Sweden.
    Uvdal, Kajsa
    Division of Molecular Surface Physics and Nanoscience, Department of Physics, Chemistry and Biology, Linköping University, Linköping, Sweden.
    Effects of gadolinium oxide nanoparticles on the oxidative burst from human neutrophil granulocytes2012Inngår i: Nanotechnology, ISSN 0957-4484, E-ISSN 1361-6528, Vol. 23, nr 27, artikkel-id 275101Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    We have previously shown that gadolinium oxide (Gd2O3) nanoparticles are promising candidates to be used as contrast agents in magnetic resonance (MR) imaging applications. In this study, these nanoparticles were investigated in a cellular system, as possible probes for visualization and targeting intended for bioimaging applications. We evaluated the impact of the presence of Gd2O3 nanoparticles on the production of reactive oxygen species (ROS) from human neutrophils, by means of luminol-dependent chemiluminescence. Three sets of Gd2O3 nanoparticles were studied, i.e. as synthesized, dialyzed and both PEG-functionalized and dialyzed Gd2O3 nanoparticles. In addition, neutrophil morphology was evaluated by fluorescent staining of the actin cytoskeleton and fluorescence microscopy. We show that surface modification of these nanoparticles with polyethylene glycol (PEG) is essential in order to increase their biocompatibility. We observed that the as synthesized nanoparticles markedly decreased the ROS production from neutrophils challenged with prey (opsonized yeast particles) compared to controls without nanoparticles. After functionalization and dialysis, more moderate inhibitory effects were observed at a corresponding concentration of gadolinium. At lower gadolinium concentration the response was similar to that of the control cells. We suggest that the diethylene glycol (DEG) present in the as synthesized nanoparticle preparation is responsible for the inhibitory effects on the neutrophil oxidative burst. Indeed, in the present study we also show that even a low concentration of DEG, 0.3%, severely inhibits neutrophil function. In summary, the low cellular response upon PEG-functionalized Gd2O3 nanoparticle exposure indicates that these nanoparticles are promising candidates for MR-imaging purposes.

  • 161.
    Abu Baker Karim, Aria
    et al.
    Örebro universitet, Institutionen för naturvetenskap och teknik.
    Schnelzer, Anna
    Örebro universitet, Institutionen för naturvetenskap och teknik.
    Optimering av glidlager och utveckling av dess konstruktion2012Independent thesis Basic level (university diploma), 10 poäng / 15 hpOppgave
    Abstract [sv]

    I detta projekt har vi fördjupat oss i en glidlagerkonstruktion som befinner sig i en skruvpress. Skruvpressen kompakterar en okänd massa som är sekretessbelagd. Robustus har ett förslag på överdimensionering av det nuvarande glidlagret. Målet med projektet var att analysera och optimera några glidlager i förhållande till det befintliga glidlagret samt att ta hänsyn till materialval och den miljö som lagret kommer att befinner sig i. Det som analyserna och optimeringen visade var att det befintliga glidlagret hade den bästa geometrin bland alla lösningar men inte det optimala materialet. Projektet befinner sig i ett tidigt stadium och det behövs en del geometriska förändringar. Det viktigaste av allt är att problemet har identifierats med hjälp av det havererade glidlagret och med en excelmodell.

  • 162.
    Abu Baker Karim, Sara
    et al.
    Örebro universitet, Institutionen för juridik, psykologi och socialt arbete.
    Fröjd, Linda
    Örebro universitet, Institutionen för juridik, psykologi och socialt arbete.
    "Våld som våld!"Socialsekreteras identifiering och arbete med våld i nära relationer samt hedersrelaterat våld och förtryck under utredningsprocess2014Independent thesis Basic level (professional degree), 10 poäng / 15 hpOppgave
  • 163.
    Abu Rweileh, Hatim
    et al.
    Örebro universitet, Institutionen för juridik, psykologi och socialt arbete.
    Ashna, Poya
    Örebro universitet, Institutionen för juridik, psykologi och socialt arbete.
    Stigmatisering: Klient med psykisk diagnos2012Independent thesis Basic level (professional degree), 10 poäng / 15 hpOppgave
  • 164.
    Abuabaid, Hanan
    et al.
    Örebro universitet, Institutionen för naturvetenskap och teknik.
    Karlsson, Mattias
    Örebro universitet, Institutionen för naturvetenskap och teknik.
    Scherbak, Nikolai
    Örebro universitet, Institutionen för naturvetenskap och teknik.
    Olsson, Per-Erik
    Örebro universitet, Institutionen för naturvetenskap och teknik.
    Jass, Jana
    Örebro universitet, Institutionen för naturvetenskap och teknik.
    Probiotic Lactobacillus rhamnosus alters inflammatory responses of bladder epithelial and macrophage-like cells in co-cultureManuskript (preprint) (Annet vitenskapelig)
  • 165.
    Acar, Augin
    et al.
    Örebro universitet, Handelshögskolan vid Örebro Universitet.
    Törmänen, Anton
    Örebro universitet, Handelshögskolan vid Örebro Universitet.
    Rosenberg, Daniel
    Örebro universitet, Handelshögskolan vid Örebro Universitet.
    Legitimitetssökande i en kontroversiell bransch En studie av tre spelbolags hållbarhetsredovisningar2016Independent thesis Basic level (degree of Bachelor), 10 poäng / 15 hpOppgave
  • 166.
    Acar, Daniel
    et al.
    Örebro universitet, Handelshögskolan vid Örebro universitet.
    Acar, David
    Örebro universitet, Handelshögskolan vid Örebro universitet.
    Belöningssystemet: -En fallstudie av Lantmännen Unibake2007Independent thesis Advanced level (degree of Master (One Year)), 10 poäng / 15 hpOppgave
  • 167.
    Acar, Daniel
    et al.
    Örebro universitet, Institutionen för ekonomi, statistik och informatik.
    Demaku, Visar
    Örebro universitet, Institutionen för ekonomi, statistik och informatik.
    Hur redovisar fotbollsklubbar på elitnivå sina spelare?2006Independent thesis Basic level (degree of Bachelor), 10 poäng / 15 hpOppgave
  • 168.
    Acevedo, Andres
    Örebro universitet, Institutionen för juridik, psykologi och socialt arbete.
    Transparens i svensk valkampanjfinansiering2013Independent thesis Advanced level (professional degree), 20 poäng / 30 hpOppgave
    Abstract [en]

    Despite the fact that the issue has been discussed for several decades, there are still no rules in Sweden mandating political parties and candidates to disclose received donations. Because of this lack of transparency, Sweden is not fulfilling some of its international obligations and has fallen behind in the international trend to increase the transparency of election campaign finance. The lack of disclosure rules in Sweden has led to extensive criticism, most notably from the Council of Europe´s group of states against corruption, Greco, who criticized Sweden in light of the guidelines on the subject from the Council of Europe. At this writing, a new proposal for disclosure rules is being prepared at the Department of Justice, DoJ. The proposal is to be presented in spring 2013. For the time being, the only thing that exists regarding transparency of election finance in Sweden is an agreement from 2000, struck between some of the parties in parliament, to voluntarily disclose some of their received donations.

    In 2004 a government report proposed implementing disclosure rules. The proposal received extensive criticism from the reviewing bodies regarding its compliance with the rights protection in the Swedish Instrument of Government, RF. RF provides absolute protection against the government forcing individuals to disclose their opinions in political matters and absolute protection against the government keeping records of individuals' political opinions. Since these rights are absolute, they can be restricted only by constitutional amendment. It is uncertain if disclosure rules can be considered infringements under these absolute provisions, but even if they are considered infringements, it is likely that the disclosure provisions can be designed so as not to violate the RF absolute protections. Furthermore, RF provides relative protection of the freedom of expression and association. Disclosure rules would probably not infringe the freedom of expression but are likely to be considered infringements of the freedom of association. Restrictions of the freedom of association can only be implemented in the order specified in RF and since the order for restricting the freedom of association is very rigid, it is unlikely that such a restriction would be allowed under the current RF. The DoJ has expressed that the pending proposal will not include a proposal for a constitutional amendment.

    For Sweden to fulfill its international obligations in regards of transparency in campaign finance, more extensive disclosure rules must be implemented than those included in the agreement between some parties in parliament and those included in the 2004 proposal. The DoJ has expressed, however, that the pending proposal will be modeled upon both the voluntary agreement and the 2004 proposal.

    It is therefore not entirely unlikely that the pending proposal will be either illegal under the constitution or not far reaching enough, or both.

  • 169.
    Acevedo, Andres
    Örebro universitet, Akademin för juridik, psykologi och socialt arbete.
    Verkställighetsföreskrifter inom det obligatoriska lagområdet: En kritisk granskning2011Independent thesis Basic level (degree of Bachelor), 10 poäng / 15 hpOppgave
  • 170.
    Acevedo Hermansson, Siri
    et al.
    Örebro universitet, Institutionen för juridik, psykologi och socialt arbete.
    Rooth, Lina
    Örebro universitet, Institutionen för juridik, psykologi och socialt arbete.
    ASI - verksamt eller värdelöst?: En kvalitativ undersökning om personalen på socialtjänstens tilltro till bedömningsinstrumentet ASI (Addiction Severity Index)2012Independent thesis Basic level (professional degree), 10 poäng / 15 hpOppgave
    Abstract [sv]

    Evidensbaserad praktik inom socialtjänsten förutsätter att de professionella ställer sig positiva till forskningsbaserad kunskap om insatser och användandet av bedömningsinstrument. I vår studie undersöks vilken tilltro socialarbetare på vuxenenheten i en mindre stad har till bedömningsinstrumentet Addiction Severity Index (ASI). Studien är en kvalitativ undersökning och semistrukturerade intervjuer valdes som metod för att besvara syfte och frågeställningarna. Sammanlagt har sex respondenter intervjuats varav fyra handläggare, en projektledare samt enhetschefen på verksamheten. Forskning visar att handläggare upplever olika fördelar och nackdelar i användandet av ASI. Av resultatet framgår att handläggarna använder ASI Grund regelbundet i sitt arbete men att det finns svårigheter med att implementera ASI Uppföljning. Samtliga handläggare upplever att ASI Grund är tidskrävande och har en del invändningar mot vissa av frågorna. Trots detta uttrycker de ändå att användandet av ASI kan bidra till ett rättsäkerhetsperspektiv, ett strukturerat arbetssätt och en bra grund inför behandlingsplaneringen. I studien diskuteras även förbättringsområden inom ASI. 

  • 171.
    Acevedo, Reinaldo
    et al.
    Biologic Evaluation Department, Finlay Institute of Vaccines, Havana, Cuba.
    Bai, Xilian
    Meningococcal Reference Unit, Public Health England, Manchester, UK.
    Borrow, Ray
    Meningococcal Reference Unit, Public Health England, Manchester, UK.
    Caugant, Dominique A.
    Division of Infection Control and Environmental Health, Norwegian Institute of Public Health, Oslo, Norway.
    Carlos, Josefina
    Department of Pediatrics, College of Medicine, University of the East – Ramon Magsaysay Memorial Medical Center, Quezon City, Philippines.
    Ceyhan, Mehmet
    Faculty of Medicine, Department of Pediatric Infectious Diseases, Hacettepe University, Ankara, Turkey.
    Christensen, Hannah
    Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
    Climent, Yanet
    Biologic Evaluation Department, Finlay Institute of Vaccines, Havana, Cuba.
    De Wals, Philippe
    Department of Social and Preventive Medicine, Laval University, Quebec City QC, Canada.
    Dinleyici, Ener Cagri
    Department of Paediatrics, Eskisehir Osmangazi University Faculty of Medicine, Eskisehir, Turkey.
    Echaniz-Aviles, Gabriela
    Center for Research on Infectious Diseases, Instituto Nacional de Salud Pública, Cuernavaca, México.
    Hakawi, Ahmed
    Infectious Diseases Control, Ministry of Health, Riyadh, Saudi Arabia.
    Kamiya, Hajime
    Infectious Disease Surveillance Center, National Institute of Infectious Diseases, Tokyo, Japan.
    Karachaliou, Andromachi
    Department of Veterinary Medicine, University of Cambridge, Cambridge, UK.
    Lucidarme, Jay
    Meningococcal Reference Unit, Public Health England, Manchester, UK.
    Meiring, Susan
    Division of Public Health Surveillance and Response, National Institute for Communicable Diseases, Johannesburg, South Africa.
    Mironov, Konstantin
    Central Research Institute of Epidemiology, Moscow, Russian Federation.
    Safadi, Marco A. P.
    Department of Pediatrics, FCM Santa Casa de São Paulo School of Medical Sciences, São Paulo, Brazil.
    Shao, Zhujun
    National Institute for Communicable Disease Control and Prevention, Chinese Centre for Disease Control and Prevention, Beijing, China.
    Smith, Vinny
    Meningitis Research Foundation, Bristol, UK.
    Steffen, Robert
    Department of Epidemiology and Prevention of Infectious Diseases, WHO Collaborating Centre for Travellers’ Health, University of Zurich, Zurich, Switzerland.
    Stenmark, Bianca
    Örebro universitet, Institutionen för medicinska vetenskaper. Region Örebro län. Department of Laboratory Medicine.
    Taha, Muhamed-Kheir
    Institut Pasteur, National Reference Centre for Meningococci, Paris, France.
    Trotter, Caroline
    Department of Veterinary Medicine, University of Cambridge, Cambridge, UK.
    Vazquez, Julio A.
    National Centre of Microbiology, Institute of Health Carlos III, Madrid, Spain.
    Zhu, Bingqing
    National Institute for Communicable Disease Control and Prevention, Chinese Centre for Disease Control and Prevention, Beijing, China.
    The Global Meningococcal Initiative meeting on prevention of meningococcal disease worldwide: Epidemiology, surveillance, hypervirulent strains, antibiotic resistance and high-risk populations2019Inngår i: Expert Review of Vaccines, ISSN 1476-0584, E-ISSN 1744-8395, Vol. 18, nr 1, s. 15-30Artikkel, forskningsoversikt (Fagfellevurdert)
    Abstract [en]

    Introduction: The 2018 Global Meningococcal Initiative (GMI) meeting focused on evolving invasive meningococcal disease (IMD) epidemiology, surveillance, and protection strategies worldwide, with emphasis on emerging antibiotic resistance and protection of high-risk populations. The GMI is comprised of a multidisciplinary group of scientists and clinicians representing institutions from several continents.

    Areas covered: Given that the incidence and prevalence of IMD continually varies both geographically and temporally, and surveillance systems differ worldwide, the true burden of IMD remains unknown. Genomic alterations may increase the epidemic potential of meningococcal strains. Vaccination and (to a lesser extent) antimicrobial prophylaxis are the mainstays of IMD prevention. Experiences from across the globe advocate the use of conjugate vaccines, with promising evidence growing for protein vaccines. Multivalent vaccines can broaden protection against IMD. Application of protection strategies to high-risk groups, including individuals with asplenia, complement deficiencies and human immunodeficiency virus, laboratory workers, persons receiving eculizumab, and men who have sex with men, as well as attendees at mass gatherings, may prevent outbreaks. There was, however, evidence that reduced susceptibility to antibiotics was increasing worldwide.

    Expert commentary: The current GMI global recommendations were reinforced, with several other global initiatives underway to support IMD protection and prevention.

  • 172.
    Ackfjärd, Rickard
    et al.
    Örebro universitet, Handelshögskolan vid Örebro Universitet.
    Karlsson, Mattias
    Örebro universitet, Handelshögskolan vid Örebro Universitet.
    Förslag till ett nytt ramverk för utvärdering och utveckling av ARP-poisoning-skydd2016Independent thesis Basic level (degree of Bachelor), 10 poäng / 15 hpOppgave
  • 173.
    Acosta, Stefan
    et al.
    Vascular Center, Malmö University Hospital, Malmö, Sweden.
    Block, Tomas
    Department of Surgical Sciences, Vascular Surgery, Uppsala University, Uppsala, Sweden.
    Björnsson, Steinarr
    Vascular Center, Malmö University Hospital, Malmö, Sweden.
    Resch, Timothy
    Vascular Center, Malmö University Hospital, Malmö, Sweden.
    Björck, Martin
    Department of Surgical Sciences, Vascular Surgery, Uppsala University, Uppsala, Sweden.
    Nilsson, Torbjörn
    Örebro universitet, Institutionen för hälsovetenskap och medicin. Department of Clinical Chemistry, Örebro University Hospital, Örebro, Sweden.
    Diagnostic pitfalls at admission in patients with acute superior mesenteric artery occlusion2012Inngår i: Journal of Emergency Medicine, ISSN 0736-4679, E-ISSN 1090-1280, Vol. 42, nr 6, s. 635-641Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    BACKGROUND: Acute superior mesenteric artery (SMA) occlusion leads to acute intestinal ischemia and is associated with high mortality. Early diagnosis is often missed, and confounding factors leading to diagnostic delays need to be highlighted.

    OBJECTIVES: To identify potential diagnostic laboratory pitfalls at admission in patients with acute SMA occlusion.

    METHODS: Fifty-five patients with acute SMA occlusion were identified from the in-hospital register during a 4-year period, 2005-2009.

    RESULTS: The median age was 76 years; 78% were women. The occlusion was embolic in 53% and thrombotic in 47% of patients. At admission, troponin I was above the clinical decision level (> 0.06 μg/L) for acute ischemic myocardial injury in 9/19 (47%) patients with embolic occlusion. Elevated pancreas amylase and normal plasma lactate were found in 12/45 and 13/27, respectively. A troponin I (TnI) above the clinical decision level was associated with a high frequency of referrals from the general surgeon to a specialist in internal medicine (p = 0.011) or a cardiologist (p = 0.024). The diagnosis was established after computed tomography angiography in 98% of the patients. The overall in-hospital mortality rate was 33%. Attempting intestinal revascularization (n = 43; p < 0.001), with a 95% frequency rate of completion control of the vascular procedure, was associated with a higher survival rate, whereas referral to the cardiologist was associated with a higher mortality rate (p = 0.018).

    CONCLUSION: Elevated TnI was common in acute SMA occlusion, and referral to the cardiologist was found to be associated with adverse outcome. Elevated pancreas amylase and normal plasma lactate values are also potential pitfalls at admission in patients with acute SMA occlusion.

  • 174.
    Acosta, Stefan
    et al.
    Vascular Center, Skåne University Hospital, Malmö, Sweden.
    Nilsson, Torbjörn
    Department of Clinical Chemistry, Örebro University Hospital, Örebro, Sweden.
    Current status on plasma biomarkers for acute mesenteric ischemia2012Inngår i: Journal of Thrombosis and Thrombolysis, ISSN 0929-5305, E-ISSN 1573-742X, Vol. 33, nr 4, s. 355-361Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Clinical diagnosis of acute mesenteric ischemia is difficult. The aim of this review is to provide current status on the search for an accurate plasma biomarker for acute mesenteric ischemia. A search using the medical subject heading terms marker and mesenteric ischemia or intestinal ischemia or superior mesenteric artery occlusion or mesenteric venous thrombosis in the Medline and Embase databases from 1980 to 2011. Studies without a control group or a control group consisted of healthy individuals (human studies), or studies on intestinal reperfusion were excluded. Twenty animal and twelve human studies were identified. In human studies, the studied series of patients had a control group that had a need of laparotomy (n = 2), suspected acute mesenteric ischemia (n = 7), acute abdomen (n = 2) or systemic inflammatory response syndrome (n = 1). D: -dimer has been found to be the most consistent highly sensitive early marker, but specificity was low. The follow-up study on α-glutathione S-transferase yielded inferior sensitivity and accuracy than the preliminary study, clearly questioning the value of this marker. Intestinal fatty acid binding globulin (I-FABP) and D: -lactate are both interesting markers, but the results were conflicting. Different cut-off levels have been used in the studies on I-FABP. The encouraging preliminary result of cobalt-albumin and urinary FABP as an accurate marker needs to be addressed in other study populations. The early clinical and laboratory diagnosis of intestinal ischemia remains a challenge. None of the proposed plasma-derived tests for acute mesenteric ischemia has as yet entered routine clinical practice. The proposed biomarkers need to be evaluated in a prospective clinical research project in patients with acute abdomen.

  • 175. Acosta, Stefan
    et al.
    Nilsson, Torbjörn K
    Örebro universitet, Hälsoakademin.
    Malina, Janne
    Malina, Martin
    L-lactate after embolization of the superior mesenteric artery2007Inngår i: Journal of Surgical Research, ISSN 0022-4804, E-ISSN 1095-8673, Vol. 143, nr 2, s. 320-328Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    BACKGROUND: Plasma markers for intestinal ischemia have not proven to be accurate. The value of L-lactate is unclear. Experimental models based on open surgery confound the effects of surgical trauma with that of ischemia. The aim was to create an endovascular model for acute superior mesenteric artery thromboembolism, and then to study L-lactate and lactate dehydrogenase (LD) activity in plasma and peritoneal fluid in pigs with extensive, high-grade intestinal ischemia. MATERIALS AND METHODS: Nine pigs underwent full superior mesenteric artery embolization with 4 h of intended intestinal ischemia, whereas six were control animals. Sampling of central venous and arterial blood was performed throughout the experiment, ending with laparotomy to collect peritoneal fluid and segmental intestinal biopsies. A pathologist, blinded to the performed interventions, graded the ischemic lesions. RESULTS: There were no differences in plasma L-lactate (P = 0.61) or LD activity levels (P = 0.69), measured at different time points from baseline to end of study, between animals with extensive, high-grade intestinal ischemia and sham. Intraperitoneal L-Lactate (P = 0.005) and LD activity (P = 0.018) levels were elevated compared with sham. There were differences in grades of ischemia in the duodenum (P = 0.003), small intestine (P < 0.001), proximal (P < 0.001), and sigmoid (P = 0.032) colon between experimental animals and sham. The grade of small bowel ischemia (n = 15) correlated to intraperitoneal fluid L-lactate (r = 0.80; P < 0.001) and LD activity levels (r = 0.72; P = 0.003). CONCLUSIONS: This endovascular study in a porcine model showed that L-lactate and LD activity levels in peritoneal fluid, not in plasma, reflect intestinal ischemia. The study suggests that plasma L-lactate not is a useful early marker in patients with suspicion of intestinal ischemia.

  • 176.
    Adam, Eva
    et al.
    Örebro universitet, Institutionen för humaniora, utbildnings- och samhällsvetenskap.
    Malek, Michelle
    Örebro universitet, Institutionen för humaniora, utbildnings- och samhällsvetenskap.
    Stödinsatser: En kvalitativ studie om hur pedagoger upplever sitt arbete i skolan med elever med läs- och skrivsvårigheter2014Independent thesis Basic level (professional degree), 10 poäng / 15 hpOppgave
  • 177.
    Adam, Linnea
    et al.
    Örebro universitet, Hälsoakademin.
    Saied, Morsal
    Familjefokuserad omvårdnad: Barn med kroniska sjukdomar2011Independent thesis Basic level (degree of Bachelor), 10 poäng / 15 hpOppgave
  • 178.
    Adami, Melodi
    et al.
    Örebro universitet, Institutionen för juridik, psykologi och socialt arbete.
    Skagerkvist, Elin
    Örebro universitet, Institutionen för juridik, psykologi och socialt arbete.
    Vägen tillbaka till mitt barn - En kvalitativ studie om hur mammor som under gerillakrig separerats från sina spädbarn, upplever återföreningen2015Independent thesis Advanced level (degree of Master (Two Years)), 20 poäng / 30 hpOppgave
  • 179.
    Adamic, M.
    et al.
    Dermatol Ctr Parmova, Ljubljana, Slovenia.
    Pavlovic, M. D.
    Dermatol Ctr Parmova, Ljubljana, Slovenia; Fac Med, Univ Maribor, Maribor, Slovenia.
    Rubin, A. Troilius
    Ctr Laser & Vasc Anomalies, Dept Dermatol, Skåne Univ Hosp, Malmö, Sweden.
    Palmetun-Ekback, M.
    Region Örebro län. Dept Dermatol, Örebro University Hospital, Örebro, Sweden.
    Boixeda, P.
    Dept Dermatol, Laser Serv, Ramon & Cajal Hosp, Univ Alcala De Henares, Madrid, Spain.
    Guidelines of care for vascular lasers and intense pulse light sources from the European Society for Laser Dermatology2015Inngår i: Journal of the European Academy of Dermatology and Venereology, ISSN 0926-9959, E-ISSN 1468-3083, Vol. 29, nr 9, s. 1661-1678Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    AimLasers and non-coherent intense pulse light sources (IPLS) are based on the principle of selective photothermolysis and can be used for the treatment of many vascular skin lesions. A variety of lasers has been developed for the treatment of congenital and acquired vascular lesions which incorporate these concepts into their design. Although laser and light sources are very popular due to their non-invasive nature, caution should be considered by practitioners and patients to avoid permanent side-effects. The aim of these guidelines is to give evidence-based recommendations for the use of lasers and IPLS in the treatment of vascular lesions. MethodsThese guidelines were produced by a Consensus Panel made up of experts in the field of vascular laser surgery under the auspices of the European Society of Laser Dermatology. Recommendations on the use of vascular lasers and IPLS were made based on the quality of evidence for efficacy, safety, tolerability, cosmetic outcome, patient satisfaction/preference and, where appropriate, on the experts' opinion. The recommendations of these guidelines are graded according to the American College of Chest Physicians Task Force recommendations on Grading Strength of Recommendations and Quality of Evidence in Clinical Guidelines. ResultsLasers and IPLS are very useful and sometimes the only available method to treat various vascular lesions. It is of a paramount importance that the type of laser or IPLS and their specific parameters are adapted to the indication but also that the treating physician is familiar with the device to be used. The crucial issue in treating vascular lesions is to recognize the immediate end-point after laser treatment. This is the single most important factor to ensure both the efficacy of the treatment and avoidance of serious side-effects.

  • 180.
    Adamovic, Tatjana
    et al.
    Dept Mol Med & Surg, Karolinska Inst, Stockholm, Sweden.
    McAllister, Donna
    Dept Surg, Med Coll Wisconsin, Milwaukee WI, USA.
    Wang, Tao
    Dept Biostat, Dept Populat Hlth, Med Coll Wisconsin, Milwaukee WI, USA.
    Adamovic, Dragan
    Örebro universitet, Akademin för naturvetenskap och teknik.
    Rowe, J. Jordi
    Dept Anat Pathol, Cleveland Clin, Cleveland OH, USA.
    Moreno, Carol
    Dept Physiol, Med Coll Wisconsin, Milwaukee WI, USA; Human & Mol Genet Ctr, Med Coll Wisconsin, Milwaukee WI, USA.
    Lazar, Josef
    Human & Mol Genet Ctr, Med Coll Wisconsin, Milwaukee WI, USA; Dept Dermatol, Med Coll Wisconsin, Milwaukee WI, USA.
    Jacob, Howard J.
    Dept Physiol, Med Coll Wisconsin, Milwaukee WI, USA; Med Coll Wisconsin, Human & Mol Genet Ctr, Milwaukee WI, USA; Dept Pediat, Med Coll Wisconsin, Milwaukee WI, USA.
    Sugg, Sonia L.
    Dept Surg, Univ Iowa, Iowa City IA, USA.
    Identification of novel carcinogen-mediated mammary tumor susceptibility loci in the rat using the chromosome substitution technique2010Inngår i: Genes, Chromosomes and Cancer, ISSN 1045-2257, E-ISSN 1098-2264, Vol. 49, nr 11, s. 1035-1045Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    We here report the genetic basis for susceptibility and resistance to carcinogen-mediated [7,12-dimethylbenz[a] anthracene (DMBA)] mammary tumorigenesis using the full panel of SS/BN consomic rat strains, in which substitutions of individual chromosomes from the resistant BN strain onto the genomic background of the susceptible SS strain were made. Analysis of 252 consomic females identified rat mammary Quantitative Trait Loci (QTLs) affecting tumor incidence on chromosomes 3 and 5, latency on chromosomes 3, 9, 14, and 19, and multiplicity on chromosomes 13, 16, and 19. In addition, we unexpectedly identified a novel QTL on chromosome 6 controlling a lethal toxic phenotype in response to DMBA. Upon further investigation with chromosomes 6 and 13 congenic lines, in which an additional 114 rats were investigated, we mapped (1) a novel mammary tumor QTL to a region of 27.1 Mbp in the distal part of RNO6, a region that is entirely separated from the toxicity phenotype, and (2) a novel and powerful mammary tumor susceptibility locus of 4.5 Mbp that mapped to the proximal q-arm of RNO13. Comparison of genetic strain differences using existing rat genome databases enabled us to further construct priority lists containing single breast cancer candidate genes within the defined QTLs, serving as potential functional variants for future testing.

  • 181.
    Adams, A.
    et al.
    Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom.
    Kalla, R.
    Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom.
    Vatn, S.
    Institute of Clinical Medicine, EpiGen, University of Oslo, Oslo, Norway.
    Bonfiglio, F.
    BioCruces Health Research Institue, Bilbao, Spain.
    Nimmo, E.
    Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom.
    Kennedy, N.
    Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom.
    Ventham, N.
    Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom.
    Vatn, M.
    Institute of Clinical Medicine, EpiGen, University of Oslo, Oslo, Norway.
    Ricanek, P.
    Department of Gastroenterology, Akershus University, Akershus, Norway.
    Bergemalm, Daniel
    Örebro universitet, Institutionen för medicinska vetenskaper. Region Örebro län. Department of Gastroenterology, Örebro University Hospital, Örebro, Sweden.
    Halfvarson, Jonas
    Örebro universitet, Institutionen för medicinska vetenskaper. Region Örebro län. Department of Gastroenterology, Örebro University Hospital, Örebro, Sweden.
    Söderholm, J.
    Department of Surgery, Linköping University Hospital, Linköping, Sweden;.
    Pierik, M.
    Department of Gastroenterology and Hepatology, Maastricht University Medical Center (MUMC), Maastricht, Netherlands.
    Törkvist, L.
    Department of Clinical Science, Intervention and Technology, Karolinska Institute, Stockholm, Sweden.
    Gomollon, F.
    University Hospital Clinic Lozano Blesa, Zaragoza, Spain.
    Gut, I.
    CNAG-CRG Centre for Genomic Regulation, Barcelona Institute of Science and Technology, Barcelona, Spain.
    Jahnsen, J.
    Institute of Clinical Medicine, EpiGen, University of Oslo, Oslo, Norway.
    Satsangi, J.
    Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom.
    Epigenetic alterations at diagnosis predict susceptibility, prognosis and treatment escalation in inflammatory bowel disease - IBD Character2017Inngår i: Journal of Crohn's & Colitis, ISSN 1873-9946, E-ISSN 1876-4479, Vol. 11, nr Suppl. 1, s. S108-S108Artikkel i tidsskrift (Fagfellevurdert)
  • 182.
    Adams, Richard
    et al.
    University of Exeter Business School, Exeter, UK.
    Alexander, Allen
    University of Exeter Business School, Exeter, UK.
    Öberg, Christina
    Örebro universitet, Handelshögskolan vid Örebro Universitet.
    Innovation management capabilities for start-ups and spin-offs: A literature review2014Konferansepaper (Fagfellevurdert)
  • 183.
    Adams, Richard
    et al.
    University of Exeter Business School, Exeter, UK.
    Alexander, Allen
    University of Exeter Business School, Exeter, UK.
    Öberg, Christina
    Lund University, Lund, Sweden.
    Innovation management capabilities for start-ups and spin-offs: A literature review2013Konferansepaper (Fagfellevurdert)
    Abstract [en]

    A firm’s ability to innovate is critical to retaining its competitiveness and even survival: in the long run it is the capability to generate a stream of product and process changes that matters. Consequently to secure their position into the future, firms need to be able to develop, maintain and renew their Innovation Management Capability (IMC). In order to improve their firm’s IMC, managers need to know which ‘levers’ to pull. An extensive and diverse body of literature exists that has sought to identify these important factors, and several attempts at synthesis have been made which imply that organisations successfully able to innovate exhibit a number of generic characteristics. The contingency perspective presents a challenge to these views and raises questions about their universal applicability, whether or not different contexts demand different IMCs and to what extent there is variation in generic factors across different contexts. This paper presents a literature review on innovation management capability in relation to firms that are at the early stages of development, whether they are starting out or spinning-off from other organisations. Start-ups and spin-outs (SUSOs) constitute important motors for industrial change, and their IMCs are therefore important considerations. The aim of this review is to assess the pertinence of the IMC construct for organisations in the early stages of their development and uncover any contextual contingencies. The paper indicates that SUSOs are heavily reliant on their linkages, networks and connectivity. This would seem intuitive as at the outset a firm can benefit from having mentors, partners and networks. In the open innovation paradigm, where connectivity and links are essential, this is reinforced. The paper also indicates that the IMC is described somewhat differently for SUSOs than in the general literature, a finding that emphasises how firm newness impacts IMC.

  • 184.
    Adamsson, Greta
    et al.
    Örebro universitet, Institutionen för juridik, psykologi och socialt arbete.
    Meier Kjellström, Carolina
    Örebro universitet, Institutionen för juridik, psykologi och socialt arbete.
    Frivillgorganisationer som exekutörer av sociala insatser - En kvalitativ studie om driftformen för projektet Bostad Först i Örebro kommun2014Independent thesis Basic level (professional degree), 10 poäng / 15 hpOppgave
  • 185.
    Adamsson, Hanna
    et al.
    Örebro universitet, Handelshögskolan vid Örebro universitet.
    Lunander, Anna
    Örebro universitet, Handelshögskolan vid Örebro universitet.
    Rotary - En fallstudie: Betydelsen av en splittring i varumärkesidentiteten2009Independent thesis Advanced level (degree of Master (One Year)), 10 poäng / 15 hpOppgave
  • 186.
    Adamsson, Hanna
    et al.
    Örebro universitet, Handelshögskolan vid Örebro universitet.
    Lunander, Anna
    Örebro universitet, Handelshögskolan vid Örebro universitet.
    Zukanovic, Sandra
    Örebro universitet, Handelshögskolan vid Örebro universitet.
    facebook: En ny kommunikationskanal med stora möjligheter2008Independent thesis Basic level (degree of Bachelor), 10 poäng / 15 hpOppgave
  • 187.
    Adamsson, Heidi
    Örebro universitet, Institutionen för hälsovetenskaper.
    Sjuksköterskors upplevelser av telefonrådgivning: En litteraturstudie2017Independent thesis Basic level (degree of Bachelor), 10 poäng / 15 hpOppgave
  • 188.
    Adamsson, Madelen
    et al.
    Örebro universitet, Akademin för juridik, psykologi och socialt arbete.
    Dahlgren, Leah
    Örebro universitet, Akademin för juridik, psykologi och socialt arbete.
    Anhörigstöd: Kvalitativ utvärdering av samverkan mellan Lindesbergs kommun och frivilliga verksamheter2008Independent thesis Basic level (professional degree), 10 poäng / 15 hpOppgave
  • 189.
    Adamsson, Sara
    Örebro universitet, Institutionen för humaniora, utbildnings- och samhällsvetenskap.
    Att integrera trygghet i planeringen: En fallstudie av Örebro kommuns trygghetsarbete i Vivalla2013Independent thesis Basic level (degree of Bachelor), 10 poäng / 15 hpOppgave
  • 190.
    Adamsson, Sofia
    Örebro universitet, Institutionen för juridik, psykologi och socialt arbete.
    "För oss är matchningen A och O": En studie om matchning mellan barn och familjehem2013Independent thesis Basic level (professional degree), 10 poäng / 15 hpOppgave
  • 191.
    Adan, Farhiya
    et al.
    Örebro universitet, Institutionen för juridik, psykologi och socialt arbete.
    Schibort, Olivia
    Örebro universitet, Institutionen för juridik, psykologi och socialt arbete.
    Privacy invasions and their association with poor parent-adolescent relationship2019Independent thesis Basic level (degree of Bachelor), 10 poäng / 15 hpOppgave
    Abstract [en]

    In this study we examine whether privacy invasions are associatedwith poor parent-adolescent relationship. We also examined if therewere differences between mothers and fathers in the frequency oftheir invasions, as well as the intent of those invasions. Lastly, welooked at associations between privacy invasions and parentadolescentrelationships and if these were modified by parent oradolescent gender. We hypothesized that intentional and frequentprivacy invasions would have a stronger association with poorparent-adolescent relationship than accidental and infrequentinvasions of privacy. The data for this study was selected from alarger database. Participants consisted of 78 adolescents, 39 girlsand 39 boys. Data were collected through questionnaires that bothadolescent and parent answered separately. The adolescents filledout the questionnaires at school in different classrooms. Weconcluded that frequent privacy invasions had a significantassociation with poor parent-adolescent relationship for mothers,but not fathers. Furthermore, the interaction between the frequencyof privacy invasions and the intent was significant for mattering tomothers. However, no significant relations were found for fathers.

  • 192.
    Adawi, Ali
    et al.
    Örebro universitet, Handelshögskolan vid Örebro Universitet.
    Björnius, Emil
    Örebro universitet, Handelshögskolan vid Örebro Universitet.
    "Den enes bröd, den andres spam" En studie om studenters uppfattning om och mottaglighet till e-postreklam2014Independent thesis Basic level (degree of Bachelor), 10 poäng / 15 hpOppgave
  • 193.
    Adawi, Ali
    et al.
    Örebro universitet, Handelshögskolan vid Örebro Universitet.
    Oguz, Muzaffer
    Örebro universitet, Handelshögskolan vid Örebro Universitet.
    CSR-relaterade aktiviteter i kontroversiella branscher - Tobaksbolaget Swedish Match legitimitetsförsök mellan 1999-2014.2016Independent thesis Advanced level (degree of Master (Two Years)), 20 poäng / 30 hpOppgave
  • 194.
    Adayson, Christian
    et al.
    Örebro universitet, Institutionen för naturvetenskap och teknik.
    Ashor, Denkha
    Örebro universitet, Institutionen för naturvetenskap och teknik.
    Analysering av förbättringsförslag till byggproduktion - En studie baserad på Lean2016Independent thesis Basic level (degree of Bachelor), 10 poäng / 15 hpOppgave
    Abstract [sv]

    Under senare år har produktionen inom byggbranschen utvecklats till ett mer kostsamt byggande. Det har blivit sämre produktivitet samt ökade byggfel trots vetenskaplig utveckling. Det kan bland annat konstateras att 40% av medarbetarnas arbetstid går till värdeskapande arbete. Byggsektorn är ineffektiv i jämförelse med andra tillverkningsindustrier som ligger på 65-75% i produktivitet. Det framgår även att kostnaderna i byggsektorn går att minskas med 30-35%. Myndigheterna har i olika rapporter förmedlat dess nuvarande problem och branschens förnyelsebehov.

    Studien gjordes med hjälp av intervjuer och en enkät undersökning på flera byggarbetsplatser för att undersöka ifall problemet kvarstår. Vi valde att inrikta oss mot fyra olika byggföretag som arbetar med lika stora projekt. Med hjälp av detta fås en större överblick av de praktiska arbetsmomenten.

    Syftet är att erbjuda förslag till förbättring med hjälp av Lean till byggproduktionen.

    Arbetet avgränsas till att studera slöseri, ordning och reda samt ständiga förbättringar.

    Arbetet inleddes med att göra en grundlig litteraturstudie. Detta gjordes för att få en helhetsbild av Lean och även för att analysera problemet inom byggbranschen.

    Lean handlar om att göra arbetet mer effektivt genom att hantera resurser på rätt sätt. Det går ut på att eliminera onödigt slöseri samt att arbeta med ständiga förbättringar. Det är ett arbetssätt som har använts inom tillverkningsindustrin och har konstruerats av bilkoncernen Toyota. Med hänsyn till nuläget i byggbranschen ska studien undersöka vilka möjligheter Lean kan tillföra i form av effektivisering och minskning av kostnader för produktionen.

    Det som kan konstateras är att arbetsplatserna fortfarande brister i förståelse för vad slöseri är. De är inte tillräckligt informerade och prioriterar ibland fel form av slöseri. Under intervjuerna framkom det stora brister i kunskap angående frågan. Fel prioriteringar resulterar till att det blir en stökig arbetsplats som i sin tur gör det mindre miljövänligt och därmed kan orsaka arbetsskador.

    Genom att städa och hålla ordning på arbetsplatsen gei möjlighet till en större arbetsyta som är mer flexibel, ger högre kvalitet av utförandet, medarbetarnas ergonomi blir bättre och det blir mindre risk för skador.

  • 195.
    Addison, Tony
    et al.
    WIDER/UNU.
    Levin, Jörgen
    Örebro universitet, Handelshögskolan vid Örebro universitet.
    Revenue mobilization in aid-dependent countries: current and future challengesManuskript (preprint) (Annet vitenskapelig)
    Abstract [en]

    The recent financial crisis and other climate related shocks pose important challenges to fiscal policies in a number of developing countries. The best way for developing countries to respond to the tax challenges are essentially to broaden tax bases, reduce rates and improve tax administration. But equally important, the focus has also to be on economic policies that accelerate growth and expand the tax base. In many developing countries, poor public service delivery, financed with existing revenue, creates dissatisfied citizens which are unwilling to pay taxes. A legitimate and responsive state one that secures the rule of law and keeps corruption under control is important for better mobilisation of tax revenue. With regard to the mix of tax instruments trade taxes will continue to reduce its significance as an important source of revenue. This suggests that indirect taxes such as VAT and direct taxes will be of significant importance in the future. Many developing countries have very narrow tax bases, with large number of exemptions, often designed to protect the interests of powerful groups. In these circumstances broadening the base can have the advantages of raising revenue, improving economic efficiency and achieving greater redistribution. Over the long-term taxation can reduce developing countries’ dependence upon aid and increase its ownership of the development agenda and become accountable to its citizens. This would also reinforce the social contract between state, citizens and the private sector which was how efficient institutions evolved in the developed world.

  • 196.
    Addison, Tony
    et al.
    WIDER/UNU.
    Levin, Jörgen
    Örebro universitet, Handelshögskolan vid Örebro universitet.
    The determinants of tax revenue in sub-Saharan AfricaManuskript (preprint) (Annet vitenskapelig)
  • 197.
    Adediran, Gbotemi A.
    et al.
    Department of Chemistry, Umeå University, Umeå, Sweden.
    Liem-Nguyen, Van
    Örebro universitet, Institutionen för naturvetenskap och teknik. Department of Chemistry, Umeå University, Umeå, Sweden.
    Song, Yu
    Department of Forest Ecology and Management, Swedish University of Agricultural Sciences, Umeå, Sweden.
    Schaefer, Jeffra K.
    Department of Environmental Sciences, Rutgers University, New Brunswick, New Jersey, United States.
    Skyllberg, Ulf
    Department of Forest Ecology and Management, Swedish University of Agricultural Sciences, Umeå, Sweden.
    Björn, Erik
    Department of Chemistry, Umeå University, Umeå, Sweden.
    Microbial Biosynthesis of Thiol Compounds: Implications for Speciation, Cellular Uptake, and Methylation of Hg(II)2019Inngår i: Environmental Science and Technology, ISSN 0013-936X, E-ISSN 1520-5851, Vol. 53, nr 14, s. 8187-8196Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Cellular uptake of inorganic divalent mercury (Hg(II)) is a key step in microbial formation of neurotoxic methylmercury (MeHg), but the mechanisms remain largely unidentified. We show that the iron reducing bacterium Geobacter sulfurreducens produces and exports appreciable amounts of low molecular mass thiol (LMM-RSH) compounds reaching concentrations of about 100 nM in the assay medium. These compounds largely control the chemical speciation and bioavailability of Hg(II) by the formation of Hg(LMM-RS)<INF><INF><INF>2</INF></INF> </INF>complexes (primarily with cysteine) in assays without added thiols. By characterizing these effects, we show that the thermodynamic stability of Hg(II)-complexes is a principal controlling factor for Hg(II) methylation by this bacterium such that less stable complexes with mixed ligation involving LMM-RSH, OH<SUP>-</SUP>, and Cl<SUP>-</SUP> are methylated at higher rates than the more stable Hg(LMM-RS)<INF>2</INF> complexes. The Hg(II) methylation rate across different Hg(LMM-RS)<INF>2</INF> compounds is also influenced by the chemical structure of the complexes. In contrast to the current perception of microbial uptake of Hg, our results adhere to generalized theories for metal biouptake based on metal complexation with cell surface ligands and refine the mechanistic understanding of Hg(II) availability for microbial methylation.

  • 198.
    Adel Pour, Sara
    et al.
    Örebro universitet, Institutionen för juridik, psykologi och socialt arbete.
    Andersson, Tina
    Örebro universitet, Institutionen för juridik, psykologi och socialt arbete.
    Kriminella ungdomars identitetsskapande -En integrativ litteraturöversikt med teoretiska analyser2017Independent thesis Basic level (professional degree), 10 poäng / 15 hpOppgave
  • 199.
    Adem, Sana
    et al.
    Örebro universitet, Institutionen för humaniora, utbildnings- och samhällsvetenskap.
    Gäddnäs, Erin
    Örebro universitet, Institutionen för humaniora, utbildnings- och samhällsvetenskap.
    Personalarbetets förändring och uppkomsten  avPeople and Culture: En kvalitativ studie om People and Culture och hur det skiljer sig från Human Resources2017Independent thesis Basic level (degree of Bachelor), 10 poäng / 15 hpOppgave
    Abstract [en]

    In recent years, the concept of Human Resources has been characterized by stigmatization. Personnel functions with the same name have been perceived as beneficial to management and business's strategic goals rather than the promotion of employee satisfaction. People and Culture is, according to practitioners of personnel management, a new form of personnel management to counter this negative image of HR by focusing on the people of the organization. The aim of this study is to create a deeper understanding of People and Culture. Previous research provides a background for the development of personnel work and describes the impact change in the environment has on the workplace. The theoretical starting points for this study are deregulated work, organizational culture, soft Human Resource work, normative governance as well as a model for external forces for organizational change. Our qualitative study is based on semi-structured interviews with four people who work or have worked with People and Culture and a person who works with Human Resources in an organization that previously had People and Culture. The result has shown that People and Culture can first and foremost be seen as a name trend used as a standpoint to avoid preconceived notions. Secondly, People and Culture can be seen as a widening of personnel work so that cultural work and personnel issues concern the entire organization. The study  also shows that People and Culture works to incorporate the employee into the organizational culture in four stages: marketing, recruitment, socialization and development. Finally, the study's findings indicate that the People and Culture work does not differ significantly from Human Resources in terms of purpose and method. The main difference is that People and Culture is a widening of Human Resource work aimed at the entire organization to take responsibility for staff issues.

  • 200.
    Adenfelt, Gunilla
    et al.
    Örebro universitet, Hälsoakademin.
    Warnemark, Elisabeth
    Örebro universitet, Hälsoakademin.
    Arbetsskador hos sjukgymnaster: -en litteraturstudie2008Independent thesis Basic level (professional degree), 10 poäng / 15 hpOppgave
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