Complete Reference Genome Sequence of the Clinical Neisseria gonorrhoeae Strain H035, with Resistance to the Novel Antimicrobial Zoliflodacin, Identified in Japan in 2000

Golparian, Daniel; Jacobsson, Susanne; Ohnishi, Makoto; Unemo, Magnus

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Complete Reference Genome Sequence of the Clinical Neisseria gonorrhoeae Strain H035, with Resistance to the Novel Antimicrobial Zoliflodacin, Identified in Japan in 2000

Golparian, Daniel

Örebro universitet, Institutionen för medicinska vetenskaper. World Health Organization Collaborating Centre for Gonorrhoea and Other Sexually Transmitted Infections, Department of Laboratory Medicine, Microbiology, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.ORCID-id: 0000-0002-0688-2521

Jacobsson, Susanne

Ohnishi, Makoto

Department of Bacteriology I, National Institute of Infectious Diseases, Tokyo, Japan.

Unemo, Magnus

Örebro universitet, Institutionen för medicinska vetenskaper. Region Örebro län. World Health Organization Collaborating Centre for Gonorrhoea and Other Sexually Transmitted Infections, Department of Laboratory Medicine, Microbiology, Faculty of Medicine and Health, Örebro University, Örebro, Sweden; Institute for Global Health, University College London, London, United Kingdom.ORCID-id: 0000-0003-1710-2081

2023 (engelsk)Inngår i: Microbiology Resource Announcements, E-ISSN 2576-098X, Vol. 12, nr 3, artikkel-id e0113022Artikkel i tidsskrift (Fagfellevurdert) Published

Abstract [en]

Zoliflodacin is a promising novel antimicrobial in clinical development for treatment of gonorrhea; currently, it is in a global phase 3 randomized controlled clinical trial. High activity against global Neisseria gonorrhoeae strains has been shown. We present the complete reference genome of the zoliflodacin-resistant strain H035, which was identified in Japan in 2000.

sted, utgiver, år, opplag, sider

American Society for Microbiology, 2023. Vol. 12, nr 3, artikkel-id e0113022

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URN: urn:nbn:se:oru:diva-104581DOI: 10.1128/mra.01130-22ISI: 000940691300001PubMedID: 36853044Scopus ID: 2-s2.0-85150451848OAI: oai:DiVA.org:oru-104581DiVA, id: diva2:1740601

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Funding agencies:

Örebro County Council Research Committee

Foundation for Medical Research at Örebro University Hospital (Örebro, Sweden)

Tilgjengelig fra: 2023-03-01 Laget: 2023-03-01 Sist oppdatert: 2023-05-19bibliografisk kontrollert

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