Ageing in place is a global trend with high priority on the political agenda. In Sweden, as in many other countries, a transfer from high specialty hospital care to home health care is ongoing, which calls for the need of new knowledge concerning transdisciplinary teamwork, not only between professionals but also between different levels in the health care organization. The situation that unfolds when someone’s home becomes an arena for care opens a complex context, including possible conflicts between a feeling of home and a supportive and attractive workplace. To support the process of healthy ageing, and employing staff in home- and healthcare, it is important to conduct transdisciplinary research on the interaction between researchers from different disciplines, including older people and their living environment, staff performing home- and healthcare to older people living in ordinary housing and stakeholders in society. In this chapter, we will describe in what way a transdisciplinary research approach is appropriate when planning for a study, how this can contribute to research on ageing in place, and also share lessons learnt from this process.