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Individual-Level Effects of a Digital Behavioural Treatment for Chronic Pain: Proof-of-Concept of a Single-Case Experimental Design Study
Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden; Pain Clinic, Capio St. Göran's Hospital, Stockholm, Sweden.
Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden; Department of Psychiatry and Neuropsychology and Alzheimer Centrum Limburg, Mental Health and Neuroscience Research Institute, Maastricht University, Maastricht, the Netherlands.
Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Örebro universitet, Institutionen för beteende-, social- och rättsvetenskap. Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden; Pain Clinic, Capio St. Göran's Hospital, Stockholm, Sweden.ORCID-id: 0000-0001-8350-1836
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2025 (Engelska)Ingår i: European Journal of Pain, ISSN 1090-3801, E-ISSN 1532-2149, Vol. 29, nr 10, artikel-id e70128Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

BACKGROUND: Chronic pain affects 20%-30% of the population worldwide, leading to significant distress, disability and financial burden. Pain management strategies focusing on pain reduction have shown limited effects on functioning; however, behavioural treatments aimed at enhancing resilience have demonstrated strong empirical support. Digital solutions offer new opportunities for delivering evidence-based treatments, but evaluation at the individual level is needed. The aim of this study is to examine individual-level treatment effects of a digital behavioural treatment for chronic pain in a heterogeneous sample.

METHODS: A study with a single-case experimental design (SCED) was conducted with participants (N = 11) experiencing chronic pain (> 3 months) recruited through healthcare. Participants were randomised at baseline (5-10-day A-phase) and completed a 6-module digital treatment based on learning theory and well-established theories applied to chronic pain (6-8-week B-phase), with weekly therapist contact. Digital diaries, prompted twice daily, tracked psychological flexibility and acceptance, pain-related functioning, pain intensity and well-being. Data were analysed using visual analysis and effect size calculations.

RESULTS: N = 11 enrolled and data from n = 10 were analysed (n = 1 refused digital diary, n = 2 partial completers, n = 8 full completers). Pain profiles varied (e.g., chronic migraine, fibromyalgia, lower back pain, etc.). Several participants benefited from the treatment, though results varied across individuals and across outcomes.

CONCLUSION: The digital behavioural treatment showed promise in addressing diverse pain profiles and associated functioning. The variability in responses highlights the benefit of using SCED to explore individual-level effects, thus offering a methodological proof-of-concept. Findings support further development, including tailoring to match individual needs.

SIGNIFICANCE STATEMENT: This proof-of-concept study provides support for the utility of digital behavioural interventions and individual-level evaluation of treatment effects, highlighting the potential of personalised pain treatments. The findings contribute to the growing body of support for digital solutions as effective and accessible approaches to improve functioning and resilience for people with diverse pain experiences.

Ort, förlag, år, upplaga, sidor
John Wiley & Sons, 2025. Vol. 29, nr 10, artikel-id e70128
Nyckelord [en]
N‐of‐1, chronic pain, cognitive behavioural therapy, digital, self‐management, single‐case experimental design
Nationell ämneskategori
Omvårdnad Tillämpad psykologi
Identifikatorer
URN: urn:nbn:se:oru:diva-123800DOI: 10.1002/ejp.70128ISI: 001619147900004PubMedID: 40964970Scopus ID: 2-s2.0-105016705814OAI: oai:DiVA.org:oru-123800DiVA, id: diva2:1999238
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AFA FörsäkringTillgänglig från: 2025-09-19 Skapad: 2025-09-19 Senast uppdaterad: 2026-01-23Bibliografiskt granskad

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Engman, LinneaFlink, IdaBoersma, Katja

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