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On fractures of the distal radius: outcome analysis, the role of socioeconomic factors and surgical considerations
Örebro University, School of Medical Sciences.ORCID iD: 0000-0001-5610-2063
2025 (English)Doctoral thesis, comprehensive summary (Other academic)
Abstract [en]

Distal radius fractures (DRFs) are the most common fractures, yet many patients experience suboptimal recovery. Radiological parameters and patient factors guide treatment decisions, and surgical treatment is aimed at restoring the anatomy. However, the radiological result correlates poorly with the outcome, and so other factors impactingt he outcome must be considered. The present thesis addresses this matter by investigating the outcome and factors potentially influencing the outcome, such as socioeconomic factors, decreased finger motion, and surgical technique. Using data from the Swedish Fracture Register (SFR) and prospectively collected data, four studies were conducted:

• Study I: Analysed the epidemiology, treatment, and outcomes of intraarticular DRFs in the SFR.

• Study II: Examined decreased finger motion in relation to outcomes in 140 patients.

• Study III: Investigated the impact of socioeconomic factors on DRF recovery.

• Study IV: Assessed the risk of median neuropathy associated with the volar central approach in a cohort of 38 patients.

Key findings included the following: a considerable proportion of patients with intraarticular fractures experience disability 1 year after the fracture. Country of birth significantly affects DRF recovery, with non-European patients having higher risk of reported poor outcomes. Patients with decreased finger motion at 4 weeks post-surgery report worse outcomes up to 1 year after the surgery, suggesting its potential as a prognostic tool. The volar central approach carries a considerable risk of median neuropathy, and should be used only when optimal visualization of the distal radius is needed.

Place, publisher, year, edition, pages
Örebro: Örebro University , 2025. , p. 97
Series
Örebro Studies in Medicine, ISSN 1652-4063 ; 318
Keywords [en]
distal radius fracture, volar locking plate, patient-reported outcome, socioeconomic factors, median nerve, nerve conduction study, epidemiology, pulp-to-palm distance
National Category
Surgery
Identifiers
URN: urn:nbn:se:oru:diva-118896ISBN: 9789175296432 (print)ISBN: 9789175296449 (electronic)OAI: oai:DiVA.org:oru-118896DiVA, id: diva2:1931882
Public defence
2025-05-09, Örebro universitet, Campus USÖ, Tidefeltsalen, Södra Grev Rosengatan 32, Örebro, 09:00 (Swedish)
Opponent
Supervisors
Available from: 2025-01-28 Created: 2025-01-28 Last updated: 2025-06-17Bibliographically approved
List of papers
1. Treatment and outcome of AO/OTA type C distal radius fractures: 12 199 fractures from the Swedish Fracture Register
Open this publication in new window or tab >>Treatment and outcome of AO/OTA type C distal radius fractures: 12 199 fractures from the Swedish Fracture Register
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2023 (English)In: Acta Orthopaedica Belgica, ISSN 0001-6462, Vol. 89, no 2, p. 241-247Article in journal (Refereed) Published
Abstract [en]

The aim of this study was to examine the epidemiology, treatment, and patient-reported outcome of AO/OTA type C distal radius fractures (DRF) using data from a large national fracture register. We used prospectively collected data from the Swedish Fracture Register covering all AO/OTA type C DRFs registered between April 2012 and December 2018. Data on fracture type, epidemiology, trauma-mechanism, and treatment had been recorded by the treating physician. Patients had been sent an outcome questionnaire including EQ-VAS, EQ-5D, and the SMFA at the time of injury and 12 months after. A total of 12 199 cases with AO/OTA type C fracture were identified. AO/OTA type C1 fracture was most common, with 5400 cases, followed by AO type C2 with 4304 and AO/OTA type C3 with 2495. Cast treatment and surgical treatment with volar locking plate fixation were the most common treatments. Patient-reported outcome measures worsened significantly one year after the fracture, and 56% reported moderate problems with pain and discomfort one year after the fracture. Patients treated with a volar plate reported a significantly larger deterioration in EQ-5D outcome compared to patients treated with a cast. No treatment method was found to be superior. A good outcome after a type C fracture is possible, but many patients do not recover completely. Our findings indicate a relatively better self-reported outcome for patients treated with a cast, but as treatment was not randomized the clinical relevance is unclear.

Place, publisher, year, edition, pages
Belgian Society of Orthopaedics and Traumatology, 2023
Keywords
Distal radius fracture, Epidemiology, Swedish fracture register, AO, OTA type C, patient -reported outcome measures
National Category
Orthopaedics
Identifiers
urn:nbn:se:oru:diva-110865 (URN)10.52628/89.2.11473 (DOI)001124240400003 ()37924540 (PubMedID)2-s2.0-85174386730 (Scopus ID)
Funder
Region Örebro County, 939040
Available from: 2024-01-22 Created: 2024-01-22 Last updated: 2025-06-17Bibliographically approved
2. Pulp-to-palm distance after plate fixation of a distal radius fracture corresponds to functional outcome
Open this publication in new window or tab >>Pulp-to-palm distance after plate fixation of a distal radius fracture corresponds to functional outcome
2023 (English)In: Archives of physiotherapy, E-ISSN 2057-0082, Vol. 13, no 1, article id 6Article in journal (Refereed) Published
Abstract [en]

INTRODUCTION: Several factors can influence the outcome after a distal radius fracture (DRF). The aim of this study was to assess whether postoperative pulp-to-palm (PTP) distance correlated with functional outcomes after plate fixation of DRF. MATERIALS &

METHODS: This is a secondary analysis of a randomized controlled trial aimed to investigate the effects of plate fixation in patients with type-C fractures. Subjects (N = 135) were divided into 2 groups based on PTP distance (equal to or higher than 0 cm) at 4 weeks postoperatively. Outcome measures were collected prospectively at 3, 6 and 12 months and included Patient-Rated Wrist Evaluation (PRWE), Quick Disabilities of the Arm Shoulder and Hand (QuickDASH) scores, wrist range of motion (ROM), Visual Analog Scale (VAS) pain scores, and hand grip strength.

RESULTS: Overall, at 3 and 6 months patients with PTP > 0 cm had significantly worse outcomes (PRWE, QuickDASH, wrist ROM) than those with PTP =0 cm. At 12 months, QuickDASH and wrist ROM were still significantly worse. In the volar-plating subgroup, patients with PTP > 0 cm had significantly worse wrist ROM and grip strength at 3 months, but no significant differences were found in subsequent follow-ups. In the combined-plating group, patients with PTP > 0 cm had significantly worse QuickDASH, wrist ROM and grip strength at 3 months. At 6 and 12 months, wrist ROM was still significantly worse.

CONCLUSIONS: Measurement of PTP distance appears to be useful to identify patients likely to have worse outcome after plating of a DRF. This could be a tool to improve the allocation of hand rehabilitation resources.

Place, publisher, year, edition, pages
BioMed Central (BMC), 2023
Keywords
Distal radius fracture, Outcome, Patient-related outcome measures, Plating, Pulp-to-palm distance, Rehabilitation, Wrist function
National Category
Orthopaedics
Identifiers
urn:nbn:se:oru:diva-105118 (URN)10.1186/s40945-023-00159-4 (DOI)000999922000001 ()36941730 (PubMedID)2-s2.0-85150932411 (Scopus ID)
Available from: 2023-03-22 Created: 2023-03-22 Last updated: 2025-06-17Bibliographically approved
3. Socioeconomic factors associated with poor patient-reported outcomes of 17,478 patients after a distal radial fracture
Open this publication in new window or tab >>Socioeconomic factors associated with poor patient-reported outcomes of 17,478 patients after a distal radial fracture
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2025 (English)In: Journal of Hand Surgery, European Volume, ISSN 1753-1934, E-ISSN 2043-6289, Vol. 50, no 7, p. 956-964Article in journal (Refereed) Published
Abstract [en]

This study aimed to investigate the association of socioeconomic factors, country of birth and comorbidities with poor patient-reported outcome 1 year after a distal radial fracture. The patient population was obtained from the Swedish Fracture Register. In the study, 17,468 patients 18 years or older were included. Poor outcome was the dependent variable in a multivariate logistic regression analysis. The factors with the strongest association with poor outcome were country of birth outside the European Union (odds ratio (OR) = 2.28; 95% CI = 1.91-2.73), high-energy trauma mechanism (OR = 1.76; 95% CI = 1.46-2.12), a history of anxiety or depression (OR = 1.46; 95% CI = 1.26-1.70), and a Charlson comorbidity index ≥3 (OR = 1.51; 95% CI = 1.17-1.94). Alleviating the effects of these factors could potentially decrease the proportion of patients with a disability after a distal radial fracture.Level of evidence: III.

Place, publisher, year, edition, pages
Sage Publications, 2025
Keywords
Comorbidity, Short Musculoskeletal Function Assessment, country of birth, distal radial fracture, socioeconomic factors, wrist fracture
National Category
Orthopaedics
Identifiers
urn:nbn:se:oru:diva-117171 (URN)10.1177/17531934241293426 (DOI)001347198200001 ()39487749 (PubMedID)2-s2.0-85208176687 (Scopus ID)
Funder
Region Örebro County, 979859
Note

This study was supported by grants from Örebro County Council (ALF-project, grant number: 979859) and the Örebro County Research Committee [grant number: 964508 and 938725].

Available from: 2024-11-04 Created: 2024-11-04 Last updated: 2025-09-08Bibliographically approved
4. The volar central approach for distal radius fractures: A prospective nerve conduction study of 38 patients
Open this publication in new window or tab >>The volar central approach for distal radius fractures: A prospective nerve conduction study of 38 patients
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(English)Manuscript (preprint) (Other academic)
National Category
Surgery
Identifiers
urn:nbn:se:oru:diva-120445 (URN)
Available from: 2025-04-08 Created: 2025-04-08 Last updated: 2025-04-29Bibliographically approved

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