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Wound Cleansing in Chronic Wound Management: Evidence, Measurement, and Clinical Practice
Örebro University, School of Health Sciences.
2026 (English)Doctoral thesis, comprehensive summary (Other academic)
Abstract [en]

Wound cleansing is widely regarded as a foundational component of chronic wound management; however, the empirical evidence supporting commonly recommended cleansing techniques remains limited. Much of the guidance informing current practice is derived from acute wound models, laboratory studies, and expert consensus rather than from comparative studies conducted in chronic wound populations.

The aim of this thesis was to examine the evidence base for wound cleansing practices in chronic wounds and to investigate nurses’ knowledge, attitudes, and practice related to wound cleansing.

The thesis comprises four studies. Study I systematically reviewed evidence comparing irrigation and swabbing techniques in chronic wounds. Study II developed and psychometrically evaluated a questionnaire measuring nurses’ knowledge, attitudes, and practices related to wound cleansing. Study III applied the instrument in an international cross-sectional survey. Study IV conducted confirmatory factor analysis to evaluate the internal structure of the attitudes subscale.

The review identified extremely limited chronic wound-specific evidence for commonly recommended cleansing techniques. The developed instrument demonstrated acceptable psychometric properties. Survey findings showed variation in clinician knowledge and practice, with higher knowledge associated with formal wound care education. Confirmatory analysis supported the multidimensional structure of nurses’ attitudes.

These findings highlight the need for stronger empirical evidence and structured education to support evidence-informed cleansing practices.

Place, publisher, year, edition, pages
Örebro: Örebro University , 2026. , p. 80
Series
Örebro Studies in Medicine, ISSN 1652-4063 ; 359
Keywords [en]
chronic wounds, wound cleansing, wound irrigation, biofilm, nursing practice, knowledge-attitude-practice, questionnaire development, psychometric validation
National Category
Other Health Sciences
Identifiers
URN: urn:nbn:se:oru:diva-127907ISBN: 9789175297866 (print)ISBN: 9789175297873 (electronic)OAI: oai:DiVA.org:oru-127907DiVA, id: diva2:2045315
Public defence
2026-06-12, Örebro universitet, Forumhuset, Hörsal F, Fakultetsgatan 1, Örebro, 13:00 (English)
Opponent
Supervisors
Available from: 2026-03-12 Created: 2026-03-12 Last updated: 2026-06-04Bibliographically approved
List of papers
1. Wound irrigation versus swabbing technique for cleansing noninfected chronic wounds: A systematic review of differences in bleeding, pain, infection, exudate, and necrotic tissue
Open this publication in new window or tab >>Wound irrigation versus swabbing technique for cleansing noninfected chronic wounds: A systematic review of differences in bleeding, pain, infection, exudate, and necrotic tissue
Show others...
2023 (English)In: Journal of tissue viability, ISSN 0965-206X, Vol. 32, no 1, p. 136-143Article, review/survey (Refereed) Published
Abstract [en]

PURPOSE: To systematically summarize and review the existing literature to determine the difference between wound cleansing techniques, irrigation and swabbing, in relation to bleeding, pain, infection, necrotic tissue and exudate in non-infected chronic wounds including pressure injuries, venous and arterial leg ulcers and diabetic foot ulcers.

METHODS: A systematic search of the electronic databases Ovid Medline, Cochrane Database of Systematic Reviews, Cumulative Index to Nursing and Allied Health Literature (CINAHL), and EMBASE was performed to identify all relevant literature in English. The search also included systematic reviews as a method to obtain additional potential citations by manually searching the reference lists. Included studies were assessed for methodological quality using the Cochrane Risk of Bias Tool.

RESULTS: One study met eligibility criteria. Two hundred fifty six patients with wounds healing via secondary intention (n = 256) were included. Wound cleansing via swabbing technique was associated with increased perception of pain and increased rates of infection when compared to the irrigation group (93.4% versus 84.2% p = 0.02 and 5.2% versus 3.3% p = 0.44, respectively). Only a small proportion of this sample met the inclusion criteria, so the results are not considered externally valid.

CONCLUSION: Wound cleansing remains a controversial topic. Despite calls for further research, there continues to remain a large gap in evidence to guide practice. Irrigation continues to replace swabbing in the management of chronic wounds, although evidence of improved outcomes is virtually nonexistent. Although the one study identified was of sound methodological quality, chronic wounds accounted for only a small percentage of the sample. Therefore, results are not generalizable to those with chronic wounds. Further research is needed to determine the effectiveness of basic wound cleansing techniques before considering more costly products.

Place, publisher, year, edition, pages
Elsevier, 2023
Keywords
Bleeding, Chronic wound, Cleansing, Exudate, Infection, Necrotic tissue, Pain
National Category
Surgery
Identifiers
urn:nbn:se:oru:diva-102532 (URN)10.1016/j.jtv.2022.11.002 (DOI)000950431000001 ()36462962 (PubMedID)2-s2.0-85143122489 (Scopus ID)
Available from: 2022-12-05 Created: 2022-12-05 Last updated: 2026-05-20Bibliographically approved
2. Knowledge, attitudes, and practices (KAP) of nurses towards wound cleansing: design and evaluation of measurement properties of a questionnaire
Open this publication in new window or tab >>Knowledge, attitudes, and practices (KAP) of nurses towards wound cleansing: design and evaluation of measurement properties of a questionnaire
2026 (English)In: Journal of tissue viability, ISSN 0965-206X, Vol. 35, no 1, article id 100967Article in journal (Refereed) Published
Abstract [en]

BACKGROUND: Wound cleansing is a fundamental component of chronic wound management; yet, high-quality evidence to guide practice is limited. Understanding nurses' knowledge, attitudes, and practices (KAP) is essential, but no instrument with published evidence of acceptable measurement properties exists.

OBJECTIVE: To develop a KAP questionnaire on wound cleansing for community nurses and evaluate its measurement properties.

METHODS: A multi-phase study was conducted, including literature/consensus item generation; a two-round international Delphi process; pilot cognitive interviews; and field testing in Canada. Knowledge was assessed for item and construct validity; attitude for internal consistency (Cronbach's α); and all KAP items for stability using test-retest reliability.

RESULTS: 26 experts supported content relevance; feedback led to targeted revisions. Field testing involved 130 nurses (83.1 % homecare; >80 % with ≥5 years of wound care experience). Several knowledge items were too easy (≥.90); none negatively discriminated. Exploratory principal components analysis of attitudes yielded three components (63 % of variance); internal consistency ranged from α = 0.41 to α = 0.76. In the subsample (n = 30), knowledge κ values ranged from slight/fair to substantial; some items showed ceiling effects (uniform responses, κ undefined). Attitude and practice item-level intraclass correlation coefficients varied (.07-.95), with several ≥.75 and others <.60. Known-groups comparison supported higher knowledge among formally educated nurses.

CONCLUSION: Evidence supports content validity and a clarified attitudes structure; internal consistency and stability were acceptable for some elements but below the threshold for others. Future refinement and confirmatory testing are warranted.

Place, publisher, year, edition, pages
Elsevier, 2026
Keywords
Attitudes, Home care, Knowledge, Nursing, Practices, Wound cleansing
National Category
Nursing Dermatology and Venereal Diseases
Identifiers
urn:nbn:se:oru:diva-125155 (URN)10.1016/j.jtv.2025.100967 (DOI)001628456700001 ()41274134 (PubMedID)2-s2.0-105022109093 (Scopus ID)
Available from: 2025-11-24 Created: 2025-11-24 Last updated: 2026-05-20Bibliographically approved
3. Knowledge, Attitudes, and Practices of Health Care Professionals Towards Chronic Wound Cleansing: International Cross-Sectional Survey
Open this publication in new window or tab >>Knowledge, Attitudes, and Practices of Health Care Professionals Towards Chronic Wound Cleansing: International Cross-Sectional Survey
(English)Manuscript (preprint) (Other academic)
National Category
Other Health Sciences
Identifiers
urn:nbn:se:oru:diva-128956 (URN)
Available from: 2026-05-20 Created: 2026-05-20 Last updated: 2026-05-20Bibliographically approved
4. Confirmatory Evaluation of the International Structure of the Wound Cleansing KAP Attitudes Subscale
Open this publication in new window or tab >>Confirmatory Evaluation of the International Structure of the Wound Cleansing KAP Attitudes Subscale
(English)Manuscript (preprint) (Other academic)
National Category
Other Health Sciences
Identifiers
urn:nbn:se:oru:diva-128960 (URN)
Available from: 2026-05-20 Created: 2026-05-20 Last updated: 2026-05-20Bibliographically approved

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