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Long-term reoperation rate following primary ventral hernia repair: a register-based study
Örebro University, School of Medical Sciences. Departments of Surgery, School of Medical Sciences, Örebro University Hospital, Örebro University, Stockholm, Sweden; Örebro University Hospital, Faculty of Medicine and Health, Örebro University, Stockholm, Sweden; Department of Surgery, Karlskoga Hospital, Karlskoga, Sweden.ORCID iD: 0000-0002-3603-5606
Örebro University, School of Medical Sciences. Departments of Surgery, School of Medical Sciences, Örebro University Hospital, Örebro University, Stockholm, Sweden; Örebro University Hospital, Faculty of Medicine and Health, Örebro University, Stockholm, Sweden.
Department of Clinical Science and Education Södersjukhuset, Karolinska Institute, Stockholm, Sweden; Department of Surgery, Södersjukhuset, Stockholm, Sweden.
2022 (English)In: Hernia, ISSN 1265-4906, E-ISSN 1248-9204, Vol. 26, no 6, p. 1551-1559Article in journal (Refereed) Published
Abstract [en]

Background: The aim of this study was to analyse the risk for reoperation following primary ventral hernia repair.

Methods: The study was based on umbilical hernia and epigastric hernia repairs registered in the population-based Swedish National Patient Register (NPR) 2010-2019. Reoperation was defined as repeat repair after primary repair.

Results: Altogether 29,360 umbilical hernia repairs and 6514 epigastric hernia repairs were identified. There were 624 reoperations registered following primary umbilical repair and 137 following primary epigastric repairs. In multivariable Cox proportional hazard analysis, the hazard ratio (HR) for reoperation was 0.292 (95% confidence interval (CI) 0.109-0.782) after open onlay mesh repair, 0.484 (CI 0.366-0.641) after open interstitial mesh repair, 0.382 (CI 0.238-0.613) after open sublay mesh repair, 0.453 (CI 0.169-1.212) after open intraperitoneal onlay mesh repair, 1.004 (CI 0.688-1.464) after laparoscopic repair, and 0.940 (CI 0.502-1.759) after other techniques, when compared to open suture repair as reference method. Following umbilical hernia repair, the risk for reoperation was also significantly higher for patients aged < 50 years (HR 1.669, CI 1.389-2.005), for women (HR 1.401, CI 1.186-1.655), and for patients with liver cirrhosis (HR 2.544, CI 1.049-6.170). For patients undergoing epigastric hernia repair, the only significant risk factor for reoperation was age < 50 years (HR 2.046, CI 1.337-3.130).

Conclusions: All types of open mesh repair were associated with lower reoperation rates than open suture repair and laparoscopic repair. Female sex, young age and liver cirrhosis were risk factors for reoperation due to hernia recurrence, regardless of method.

Place, publisher, year, edition, pages
Springer, 2022. Vol. 26, no 6, p. 1551-1559
Keywords [en]
Primary ventral hernia, Umbilical hernia, Epigastric hernia, Hernia repair, Recurrence, Reoperation
National Category
Surgery
Identifiers
URN: urn:nbn:se:oru:diva-100287DOI: 10.1007/s10029-022-02645-3ISI: 000824981600001PubMedID: 35802262Scopus ID: 2-s2.0-85133638065OAI: oai:DiVA.org:oru-100287DiVA, id: diva2:1685405
Funder
Örebro UniversityAvailable from: 2022-08-02 Created: 2022-08-02 Last updated: 2025-04-28Bibliographically approved
In thesis
1. Surgical Treatment of Ventral Hernia and Rectus Diastasis
Open this publication in new window or tab >>Surgical Treatment of Ventral Hernia and Rectus Diastasis
2025 (English)Doctoral thesis, comprehensive summary (Other academic)
Abstract [en]

Background: Postpartum rectus abdominis diastasis (PP-RAD) and primary ventral hernias (PVH) are closely related in women. PP-RAD is caused by separation of the rectus abdominis muscles following pregnancy, leading to core instability and an increased risk of hernia formation. PP-RAD can significantly affect quality of life. The aim of this thesis was to evaluate the risk factors for ventral hernia formation and recurrence. The surgical interventions presented in the thesis aimed to reduce complication and recurrence rates and to improve the quality of life for female patients affected by PP-RAD.

Paper I aimed to evaluate reoperation rates due to recurrence in ventral hernia repairs across different genders, ages, and surgical methods. The study concluded that women and patients younger than 50 had significantly higher reoperation rates regardless of repair method.

Paper II evaluated the impact of parity and delivery method on risk of PVH. A register study on >1.5 million women. The study concluded that risk of hernia repair increased with number of pregnancies and cesarean sections were associated with higher rate of hernia repairs.

Paper III and IV are based on prospective studies evaluating a new Minimally Incision Repair method of Rectus Abdominis Diastasis (MIRRAD) as a day-case surgery. Paper III concluded that MIRRAD is a safe and effective method that can be performed on an outpatient basis, offering a less invasive option for repairing PPRAD.

Paper IV examined the impact of the MIRRAD procedure on patients' quality of life. The findings showed a significant improvement in the quality of life for women with PP-RAD.

Paper V is an RCT of 205 procedures comparing the safety and efficacy of placinga ventral hernia patch in the preperitoneal space with repairing with non-absorbable barbed sutures. The study concluded that preperitoneal ventral hernia patch is a safe and effective method with a lower recurrence rate compared to barbed suture repair.

Place, publisher, year, edition, pages
Örebro: Örebro University, 2025. p. 62
Series
Örebro Studies in Medicine, ISSN 1652-4063 ; 311
Keywords
Ventral Hernia, Rectus Abdominis Diastasis, Quality of Life
National Category
Surgery
Identifiers
urn:nbn:se:oru:diva-119073 (URN)9789175296210 (ISBN)9789175296227 (ISBN)
Public defence
2025-04-29, Örebro universitet, Campus USÖ, Tidefeltsalen, Södra Grev Rosengatan 32, 09:00 (English)
Opponent
Supervisors
Available from: 2025-02-04 Created: 2025-02-04 Last updated: 2025-04-28Bibliographically approved

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Katawazai, AWallin, Göran

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