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Laparoscopic ventral hernia repair with intraperitoneal onlay mesh
Örebro University, School of Medical Sciences.ORCID iD: 0000-0002-2090-4563
2025 (English)Doctoral thesis, comprehensive summary (Other academic)
Abstract [en]

Advancements in technology and medicine have rendered laparoscopic ventral hernia repair (LVHR) more favourable than open ventral hernia repair (OVHR). Albeit associated with risk of postoperative seroma, LVHR may reduce wound infection rates and hospital stays. However, LVHR requires accurate technique and careful patient selection.

Study I was a retrospective study conducted at the Karlskoga Hospital Hernia Centre. From January 2017 to June 2020, 876 ventral hernia operations were performed. We analysed 213 patients who underwent ventral hernia repair with Intraperitoneal Onlay Mesh without defect closure (sIPOM), IPOM with defect closure (IPOM-P), and IPOM with peritoneal bridging (IPOM-pb) and compared the incidence of postoperative seroma, discomfort, recurrence, and complications.

Study II was a randomized controlled trial with 112 participants who underwent laparoscopic ventral hernia repair between November 2018 and December 2020. The participants underwent ultrasonography at 1, 3, 6 and 12 months postoperatively. Postoperative seroma, discomfort, and complications following IPOMpb and sIPOM were analysed.

Study III was a registry-based study of the impact of COVID-19 on emergency and planned hernia repair procedures, divided into two periods; the pre non COVID-19 Period Januari 2016 - December 2019 as a control group and the COVID-19 Period Januari 2020 to December 2021 as the study group.

Study IV was a population-register study based on a retrospective cohort evaluating risk factors for postoperative pain, nausea and vomiting in 4795 patients who underwent ventral hernia repair between 2016 and 2021, with 2409 of them undergoing open ventral hernia repair surgery. Data were assembled from the Swedish ventral hernia register and Swedish perioperative register.

Study I showed that the IPOM-pb approach was as safe and feasible as conventional IPOM, requiring no additional effort from the surgeon or staff.

Study II showed lower incidence of postoperative seroma and discomfort in IPOM with peritoneal bridging in early-stage follow-ups, with no significant difference in subsequent follow-ups.

In study III the pandemic planned surgeries were impacted but the result in this study showed that there was no increase in emergency hernia operations due to delayed planned surgery. Careful observation and caution are crucial during a pandemic.

Study IV showed that postoperative pain, nausea and vomiting are more common in women, emergency surgery, younger age patients, and those who had surgery with inhalation anesthesia compared to total intravenous anesthesia.

Place, publisher, year, edition, pages
Örebro: Örebro University , 2025. , p. 73
Series
Örebro Studies in Medicine, ISSN 1652-4063 ; 301
Keywords [en]
Laparoscopic hernia surgery, Ventral hernia, IPOM
National Category
Surgery
Identifiers
URN: urn:nbn:se:oru:diva-116581ISBN: 9789175295909 (print)ISBN: 9789175295916 (electronic)OAI: oai:DiVA.org:oru-116581DiVA, id: diva2:1904141
Public defence
2025-03-28, Örebro universitet, Campus USÖ, Hörsal X1, Södra Grev Rosengatan 32, Örebro, 09:00 (English)
Opponent
Supervisors
Available from: 2024-10-08 Created: 2024-10-08 Last updated: 2025-04-02Bibliographically approved
List of papers
1. Laparoscopic ventral and incisional hernia repair using intraperitoneal onlay mesh with peritoneal bridging
Open this publication in new window or tab >>Laparoscopic ventral and incisional hernia repair using intraperitoneal onlay mesh with peritoneal bridging
2022 (English)In: Hernia, ISSN 1265-4906, E-ISSN 1248-9204, Vol. 26, no 2, p. 635-646Article in journal (Refereed) Published
Abstract [en]

Purpose: The aim of this study was to assess the feasibility and safety of a novel IPOM procedure with peritoneal bridging (IPOM-pb) for laparoscopic ventral hernia repair, and to compare the outcomes of this procedure with IPOM with- (IPOM-plus) and IPOM without (sIPOM) defect closure.

Method: A single-centre retrospective study comparing a novel IPOM technique with peritoneal bridging (IPOM-pb) with the two commonly used IPOM techniques, IPOM with defect closure (IPOM-plus) and without defect closure (sIPOM). The intraoperative and postoperative data of patients who underwent laparoscopic IPOM ventral hernia repair were reviewed. Preoperative data, recurrence, and postoperative seroma, surgical site infection, and pain, were compared.

Results: From January 2017 to June 2020, a total of 213 patients underwent laparoscopic ventral and incisional hernia repair with IPOM technique. The mean length and width of the ventral hernia was 4.4 +/- 1.8 cm and 3.6 +/- 1.4 cm, respectively, and the mean BMI was 30.1 +/- 5.2 kg/m(2). The mean operating time was 67 +/- 28 min and was longer for IPOM-pb (71 +/- 27 min), less for IPOM-plus (63 +/- 28 min), and least for sIPOM (61 +/- 26 min). The incidence of early postoperative seroma was least in IPOM-pb (1/98, 1%), and similar in the IPOM-plus (4/94, 4%) and sIPOM (1/21, 5%) group. Late postoperative seroma was found only in IPOM-plus (2, 2%). The incidence of early and late postoperative pain was relatively higher in sIPOM (3, 14%; 1, 5%, respectively) compared to IPOM-pb and IPOM-plus in the early (5, 5% and 6, 6%) and late (2, 2% and 1, 1%) postoperative period, respectively. Surgical site infection was higher in sIPOM group (3, 14%), compared to IPOM-pb (1, 1%), and IPOM-plus (3, 3%). Recurrence rates were similar in IPOM-pb group (3/98, 3%) and IPOM-plus (3/94, 3%), and none in sIPOM (0/21).

Conclusion: IPOM with peritoneal bridging is as feasible and safe as conventional IPOM with defect closure and simple non-defect closure. However, a large randomised controlled trial is required to confirm this finding.

Place, publisher, year, edition, pages
Springer, 2022
Keywords
Laparoscopic surgery, Ventral hernia, IPOM, Peritoneal bridging, Defect closure
National Category
Surgery
Identifiers
urn:nbn:se:oru:diva-94884 (URN)10.1007/s10029-021-02502-9 (DOI)000698877800001 ()34559335 (PubMedID)2-s2.0-85115622527 (Scopus ID)
Note

Funding agency:

Örebro University

Available from: 2021-10-13 Created: 2021-10-13 Last updated: 2025-04-02Bibliographically approved
2. Peritoneal Bridging Versus Nonclosure in Laparoscopic Ventral Hernia Repair
Open this publication in new window or tab >>Peritoneal Bridging Versus Nonclosure in Laparoscopic Ventral Hernia Repair
2023 (English)In: Annals of Surgery Open, E-ISSN 2691-3593, Vol. 4, no 1, article id e257Article in journal (Refereed) Published
Abstract [en]

Introduction: Postoperative seroma and pain are common problems following laparoscopic intraperitoneal onlay mesh (IPOM) repair of ventral hernias. These advers outcomes may be avoided by dissecting and using the peritoneum in the hernial sac to bridge the hernia defect.

Methods: This was a patient- an and outcome assesor-blinded, parallel-design, randomized controlled trial compairing nonclosure and peritoeal bridging approaches in patients schedueled for elective midline ventral hernia repair. The primary end point was seroma volume on ultrasonography. The secondary end points were postoperative pain, recurrence, and complications.

Results: Between November 2018 and December 2020, 112 patients were randomized of whom 60 were in the nonclosure group and 52 were in the peritoneal bridging group. The seroma volume in the nonclosure and peritoneal bridging groups were 17cm3(6-53cm3) versus 0cm3(0-26cm3) at 1-moth follow-up (P=0.013). The median volume was zero at 3-, 6-, and 12-month follow-ups in both groups. No significant differences were observed in early postoperative pain (P=0.447) and in recurrencerate (P=0.684). There were 4(7%) and 1(2%) perioperative complictions that lead to reoperations in simple IPOM(sIPOM) and IPOM with peritoneal bridging (IPOM-pb), respectively.

Conclusion: Seroma was less prevalent after IPOM-pb at 1-month follow-up compaired with sIPOM, with simillar posoperative pain 1 week after index of surgery in both groups. At subsequent follow-ups, the differences in seroma were not statiscally significant. Further studies are required to confirm these results. Trial registration (NCT04229940)

Keywords: epigastric hernia, incisional hernia, IPOM with fascia closure, IPOM with peritoneal bridging, laparoscopic hernia repair, simple IPOM, umblical hernia, ventral hernia

Place, publisher, year, edition, pages
Wolters Kluwer, 2023
National Category
Surgery
Identifiers
urn:nbn:se:oru:diva-105903 (URN)10.1097/as9.0000000000000257 (DOI)37600866 (PubMedID)
Available from: 2023-05-10 Created: 2023-05-10 Last updated: 2025-03-05Bibliographically approved
3. Effect of the SARS-CoV-2 pandemic on planned and emergency hernia repair in Sweden: a register-based study
Open this publication in new window or tab >>Effect of the SARS-CoV-2 pandemic on planned and emergency hernia repair in Sweden: a register-based study
2023 (English)In: Hernia, ISSN 1265-4906, E-ISSN 1248-9204, Vol. 27, no 5, p. 1103-1108Article in journal (Refereed) Published
Abstract [en]

PURPOSE: The COVID-19 has had a profound impact on the health care delivery in Sweden, including deprioritization of benign surgeries during the COVID-19 pandemic. The aim of this study was to assess the effect of COVID-19 pandemic on emergency and planned hernia repair in Sweden.

METHODS: Data on hernia repairs from January 2016 to December 2021 were retrieved from the Swedish Patient Register using procedural codes. Two groups were formed: COVID-19 group (January 2020-December 2021) and control group (January 2016-December 2019). Demographic data on mean age, gender, and type of hernia were collected.

RESULTS: This study showed a weak negative correlation between the number of elective hernia repairs performed each month during the pandemic and the number of emergency repairs carried out during the following 3 months for inguinal hernia repair (p = 0.114) and incisional hernia repair (p = 0.193), whereas there was no correlation for femoral or umbilical hernia repairs.

CONCLUSION: The COVID-19 pandemic had a great impact on planned hernia surgeries in Sweden, but our hypothesis that postponing planned repairs would increase the risk of emergency events was not supported.

Place, publisher, year, edition, pages
Springer, 2023
Keywords
Acute hernia repair, COVID-19 pandemic, Delayed hernia repair, Delayed surgery, Planned hernia repair, Postponed hernia repair
National Category
Surgery
Identifiers
urn:nbn:se:oru:diva-107063 (URN)10.1007/s10029-023-02828-6 (DOI)001020750100001 ()37418049 (PubMedID)2-s2.0-85164114066 (Scopus ID)
Available from: 2023-07-10 Created: 2023-07-10 Last updated: 2025-03-05Bibliographically approved
4. Surgery for primary ventral hernias and risk of postoperative pain, nausea: a population-based register study
Open this publication in new window or tab >>Surgery for primary ventral hernias and risk of postoperative pain, nausea: a population-based register study
Show others...
2025 (English)In: Hernia, ISSN 1265-4906, E-ISSN 1248-9204, Vol. 29, no 1, article id 68Article in journal (Refereed) Published
Abstract [en]

PURPOSE: The aim of this study was to evaluate risk factors for postoperative pain and nausea after open repair for primary ventral hernias.

METHOD: A population-based registry study was conducted based on data assembled from the Swedish national ventral hernia repair register between January 2016 and December 2021and cross-matched with the Swedish perioperative register.

RESULTS: Altogether 2064 open ventral hernia repairs were registered, including 816 (39.5%) performed on women. Of these, 91 (4.4%) were registered to suffer postoperative nausea or vomiting (PONV) and 403 (19.5%) postoperative pain (PP). In both univariable and multivariable logistic regression analyses, significant predictors of postoperative nausea and pain included male gender, which was associated with lower odds of both postoperative nausea (multivariable OR: 0.30, 95% CI: 0.18-0.49, P < 0.001) and postoperative pain (multivariable OR: 0.60, 95% CI: 0.44-0.83, P = 0.002). Additional predictors of postoperative nausea included emergency surgery (multivariable OR: 4.08, 95% CI: 1.10-15.08, P = 0.035), operative time > 40 min (multivariable OR: 4.15, 95% CI: 2.24-7.69, P < 0.001). Conversely total intravenous anesthesia was associated with lower incidence of PONV (multivariable OR: 0.40, 95% CI: 0.22-0.74, P = 0.003). Other factors, such as age, BMI, smoking status, ASA classification, hernia size, surgery type, operative time, and anesthesia type, were not significantly associated with postoperative pain after adjusting for other variables.

CONCLUSION: Postoperative nausea and vomiting (PONV) are significantly reduced with total intravenous anesthesia (TIVA) compared to inhalation anesthesia, with no notable difference in postoperative pain between the two methods.

Place, publisher, year, edition, pages
Springer Nature, 2025
Keywords
General anesthesia, Inhalation anesthesia, Postoperative pain and nausea/vomiting, Primary ventral hernia, Umbilical hernia
National Category
Surgery
Identifiers
urn:nbn:se:oru:diva-119682 (URN)10.1007/s10029-025-03256-4 (DOI)001398035000001 ()39812906 (PubMedID)2-s2.0-85215759588 (Scopus ID)
Available from: 2025-03-05 Created: 2025-03-05 Last updated: 2026-01-23Bibliographically approved

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