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2025 (English)In: Hernia, ISSN 1265-4906, E-ISSN 1248-9204, Vol. 29, no 1, article id 68Article in journal (Refereed) Published
Abstract [en]
PURPOSE: The aim of this study was to evaluate risk factors for postoperative pain and nausea after open repair for primary ventral hernias.
METHOD: A population-based registry study was conducted based on data assembled from the Swedish national ventral hernia repair register between January 2016 and December 2021and cross-matched with the Swedish perioperative register.
RESULTS: Altogether 2064 open ventral hernia repairs were registered, including 816 (39.5%) performed on women. Of these, 91 (4.4%) were registered to suffer postoperative nausea or vomiting (PONV) and 403 (19.5%) postoperative pain (PP). In both univariable and multivariable logistic regression analyses, significant predictors of postoperative nausea and pain included male gender, which was associated with lower odds of both postoperative nausea (multivariable OR: 0.30, 95% CI: 0.18-0.49, P < 0.001) and postoperative pain (multivariable OR: 0.60, 95% CI: 0.44-0.83, P = 0.002). Additional predictors of postoperative nausea included emergency surgery (multivariable OR: 4.08, 95% CI: 1.10-15.08, P = 0.035), operative time > 40 min (multivariable OR: 4.15, 95% CI: 2.24-7.69, P < 0.001). Conversely total intravenous anesthesia was associated with lower incidence of PONV (multivariable OR: 0.40, 95% CI: 0.22-0.74, P = 0.003). Other factors, such as age, BMI, smoking status, ASA classification, hernia size, surgery type, operative time, and anesthesia type, were not significantly associated with postoperative pain after adjusting for other variables.
CONCLUSION: Postoperative nausea and vomiting (PONV) are significantly reduced with total intravenous anesthesia (TIVA) compared to inhalation anesthesia, with no notable difference in postoperative pain between the two methods.
Place, publisher, year, edition, pages
Springer Nature, 2025
Keywords
General anesthesia, Inhalation anesthesia, Postoperative pain and nausea/vomiting, Primary ventral hernia, Umbilical hernia
National Category
Surgery
Identifiers
urn:nbn:se:oru:diva-119682 (URN)10.1007/s10029-025-03256-4 (DOI)001398035000001 ()39812906 (PubMedID)2-s2.0-85215759588 (Scopus ID)
2025-03-052025-03-052026-01-23Bibliographically approved