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Global Meningococcal Initiative: Insights on antibiotic resistance, control strategies and advocacy efforts in Western Europe
UK Health Security Agency, Meningococcal Reference Unit, Manchester, UK.
Immunisation Division, UK Health Security Agency, London, UK.
Norwegian Institute of Public Health, Oslo, Norway.
National Reference Center on Meningococci, Laboratory of Bacteriology, Geneva University Hospitals, Geneva, Switzerland.
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2024 (English)In: Journal of Infection, ISSN 0163-4453, E-ISSN 1532-2742, Vol. 89, no 6, article id 106335Article, review/survey (Refereed) Published
Abstract [en]

In Western Europe, many countries have robust and well-established surveillance systems and case reporting mechanisms. IMD incidence across Western Europe is low with a predominance of meningococcal serogroup B (MenB). Case confirmation and antimicrobial susceptibility testing is often standardised in this region, with many countries also having robust vaccination programmes in place. Both MenB and MenACWY vaccines form part of National Immunisation Programmes (NIPs) in most European countries, with Sweden only offering vaccination in special circumstances. Despite these established programmes, there remains a critical need for advocacy efforts in affecting change in diagnosis, testing, and treatment. Recent campaigns, such as the World Meningitis Day digital toolkit, have helped raise awareness and draw attention to meningococcal disease. Awareness around antibiotic resistance has also led to the identification of antibiotic-resistant meningococcal strains, with an increase, albeit small, in these strains noted across the region. Countries such as Spain, Portugal, Germany, Switzerland, and France have either reported strains resistant to penicillin, ciprofloxacin and/or isolates with a reduced susceptibility to third-generation cephalosporins.

Place, publisher, year, edition, pages
Elsevier, 2024. Vol. 89, no 6, article id 106335
Keywords [en]
Europe, meningococcal disease, serogroup, surveillance, vaccination
National Category
Public Health, Global Health and Social Medicine
Identifiers
URN: urn:nbn:se:oru:diva-117165DOI: 10.1016/j.jinf.2024.106335ISI: 001367358000001PubMedID: 39489181Scopus ID: 2-s2.0-85209765951OAI: oai:DiVA.org:oru-117165DiVA, id: diva2:1910257
Available from: 2024-11-04 Created: 2024-11-04 Last updated: 2025-02-20Bibliographically approved

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