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Surgical Treatment of Ventral Hernia and Rectus Diastasis
Örebro University, School of Medical Sciences.ORCID iD: 0000-0002-3603-5606
2025 (English)Doctoral thesis, comprehensive summary (Other academic)
Abstract [en]

Background: Postpartum rectus abdominis diastasis (PP-RAD) and primary ventral hernias (PVH) are closely related in women. PP-RAD is caused by separation of the rectus abdominis muscles following pregnancy, leading to core instability and an increased risk of hernia formation. PP-RAD can significantly affect quality of life. The aim of this thesis was to evaluate the risk factors for ventral hernia formation and recurrence. The surgical interventions presented in the thesis aimed to reduce complication and recurrence rates and to improve the quality of life for female patients affected by PP-RAD.

Paper I aimed to evaluate reoperation rates due to recurrence in ventral hernia repairs across different genders, ages, and surgical methods. The study concluded that women and patients younger than 50 had significantly higher reoperation rates regardless of repair method.

Paper II evaluated the impact of parity and delivery method on risk of PVH. A register study on >1.5 million women. The study concluded that risk of hernia repair increased with number of pregnancies and cesarean sections were associated with higher rate of hernia repairs.

Paper III and IV are based on prospective studies evaluating a new Minimally Incision Repair method of Rectus Abdominis Diastasis (MIRRAD) as a day-case surgery. Paper III concluded that MIRRAD is a safe and effective method that can be performed on an outpatient basis, offering a less invasive option for repairing PPRAD.

Paper IV examined the impact of the MIRRAD procedure on patients' quality of life. The findings showed a significant improvement in the quality of life for women with PP-RAD.

Paper V is an RCT of 205 procedures comparing the safety and efficacy of placinga ventral hernia patch in the preperitoneal space with repairing with non-absorbable barbed sutures. The study concluded that preperitoneal ventral hernia patch is a safe and effective method with a lower recurrence rate compared to barbed suture repair.

Place, publisher, year, edition, pages
Örebro: Örebro University , 2025. , p. 62
Series
Örebro Studies in Medicine, ISSN 1652-4063 ; 311
Keywords [en]
Ventral Hernia, Rectus Abdominis Diastasis, Quality of Life
National Category
Surgery
Identifiers
URN: urn:nbn:se:oru:diva-119073ISBN: 9789175296210 (print)ISBN: 9789175296227 (electronic)OAI: oai:DiVA.org:oru-119073DiVA, id: diva2:1934333
Public defence
2025-04-29, Örebro universitet, Campus USÖ, Tidefeltsalen, Södra Grev Rosengatan 32, 09:00 (English)
Opponent
Supervisors
Available from: 2025-02-04 Created: 2025-02-04 Last updated: 2025-04-28Bibliographically approved
List of papers
1. Long-term reoperation rate following primary ventral hernia repair: a register-based study
Open this publication in new window or tab >>Long-term reoperation rate following primary ventral hernia repair: a register-based study
2022 (English)In: Hernia, ISSN 1265-4906, E-ISSN 1248-9204, Vol. 26, no 6, p. 1551-1559Article in journal (Refereed) Published
Abstract [en]

Background: The aim of this study was to analyse the risk for reoperation following primary ventral hernia repair.

Methods: The study was based on umbilical hernia and epigastric hernia repairs registered in the population-based Swedish National Patient Register (NPR) 2010-2019. Reoperation was defined as repeat repair after primary repair.

Results: Altogether 29,360 umbilical hernia repairs and 6514 epigastric hernia repairs were identified. There were 624 reoperations registered following primary umbilical repair and 137 following primary epigastric repairs. In multivariable Cox proportional hazard analysis, the hazard ratio (HR) for reoperation was 0.292 (95% confidence interval (CI) 0.109-0.782) after open onlay mesh repair, 0.484 (CI 0.366-0.641) after open interstitial mesh repair, 0.382 (CI 0.238-0.613) after open sublay mesh repair, 0.453 (CI 0.169-1.212) after open intraperitoneal onlay mesh repair, 1.004 (CI 0.688-1.464) after laparoscopic repair, and 0.940 (CI 0.502-1.759) after other techniques, when compared to open suture repair as reference method. Following umbilical hernia repair, the risk for reoperation was also significantly higher for patients aged < 50 years (HR 1.669, CI 1.389-2.005), for women (HR 1.401, CI 1.186-1.655), and for patients with liver cirrhosis (HR 2.544, CI 1.049-6.170). For patients undergoing epigastric hernia repair, the only significant risk factor for reoperation was age < 50 years (HR 2.046, CI 1.337-3.130).

Conclusions: All types of open mesh repair were associated with lower reoperation rates than open suture repair and laparoscopic repair. Female sex, young age and liver cirrhosis were risk factors for reoperation due to hernia recurrence, regardless of method.

Place, publisher, year, edition, pages
Springer, 2022
Keywords
Primary ventral hernia, Umbilical hernia, Epigastric hernia, Hernia repair, Recurrence, Reoperation
National Category
Surgery
Identifiers
urn:nbn:se:oru:diva-100287 (URN)10.1007/s10029-022-02645-3 (DOI)000824981600001 ()35802262 (PubMedID)2-s2.0-85133638065 (Scopus ID)
Funder
Örebro University
Available from: 2022-08-02 Created: 2022-08-02 Last updated: 2025-04-28Bibliographically approved
2. Risk for ventral hernia related to parity: A populationbased register study
Open this publication in new window or tab >>Risk for ventral hernia related to parity: A populationbased register study
(English)Manuscript (preprint) (Other academic)
National Category
Surgery
Identifiers
urn:nbn:se:oru:diva-120434 (URN)
Available from: 2025-04-07 Created: 2025-04-07 Last updated: 2025-04-07Bibliographically approved
3. Minimal Incision Repair of Rectus Abdominis Muscle Diastasis (MIRRAD) as Day-Case Surgery: A Prospective Study
Open this publication in new window or tab >>Minimal Incision Repair of Rectus Abdominis Muscle Diastasis (MIRRAD) as Day-Case Surgery: A Prospective Study
(English)Manuscript (preprint) (Other academic)
National Category
Surgery
Identifiers
urn:nbn:se:oru:diva-120435 (URN)
Available from: 2025-04-07 Created: 2025-04-07 Last updated: 2025-04-07Bibliographically approved
4. Impact of Minimal Incision Repair of Rectus Abdominis Diastasis on Quality of Life and Stress Incontinence: A Prospective Study
Open this publication in new window or tab >>Impact of Minimal Incision Repair of Rectus Abdominis Diastasis on Quality of Life and Stress Incontinence: A Prospective Study
2024 (English)In: Journal of abdominal wall surgery : JAWS, E-ISSN 2813-2092, Vol. 3, article id 13830Article in journal (Refereed) Published
Abstract [en]

AIM: This study evaluates the impact of the minimal incision repair of rectus abdominis diastasis (MIRRAD) procedure on physical activity, muscle strength, quality of life, and overall satisfaction in women with postpartum rectus abdominis diastasis (PP-RAD).

METHODS: A cohort of 31 female patients, aged 20-50 years, diagnosed with PP-RAD unresponsive to conservative treatment, underwent the MIRRAD procedure. Assessments were conducted preoperatively and 1 year postoperatively, these included the Modified Abdominal Trunk Function Protocol (MATFP), Disability Rating Index (DRI), and Urinary Disability Index (UDI) questionnaires. Physical activity intensity was monitored using accelerometers. RESULTS: Significant improvements were observed in vigorous physical activities (Z = -2.352, p = 0.019), vector magnitude counts per minute (Z = -2.163, p = 0.031), and steps per minute (Z = -3.131, p = 0.002). DRI showed significant improvements in physical tasks like dressing, walking, and strenuous work (Z ranging from -2.705 to -4.603, p < 0.001). UDI indicated significant improvements in urinary symptoms, including reduced frequency (Z = -2.984, p = 0.003) and less urinary leakage (Z = -2.357, p = 0.018). MATFP demonstrated gains in back and abdominal muscle strength (Z = -4.321, p < 0.001) and trunk stability (Z = -3.991, p < 0.001).

CONCLUSION: The MIRRAD procedure significantly improves physical strength, trunk stability, and urinary function, enhancing daily activities and overall physical health in women with PP-RAD. Further research is recommended to evaluate long-term outcomes.

Place, publisher, year, edition, pages
Frontiers Media S.A., 2024
Keywords
Linea alba, postpartum rectus diastasis, quality of life, rectus abdominis diastasis, ventral hernia
National Category
Physiotherapy
Identifiers
urn:nbn:se:oru:diva-119379 (URN)10.3389/jaws.2024.13830 (DOI)001539201300001 ()39967919 (PubMedID)2-s2.0-85218199416 (Scopus ID)
Available from: 2025-02-20 Created: 2025-02-20 Last updated: 2026-01-23Bibliographically approved
5. Barbed Suture vs Preperitoneal Ventral Patch in Medium Size Ventral Hernia Repair: A Randomised Control Trial
Open this publication in new window or tab >>Barbed Suture vs Preperitoneal Ventral Patch in Medium Size Ventral Hernia Repair: A Randomised Control Trial
(English)Manuscript (preprint) (Other academic)
National Category
Surgery
Identifiers
urn:nbn:se:oru:diva-120436 (URN)
Available from: 2025-04-07 Created: 2025-04-07 Last updated: 2025-04-07Bibliographically approved

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Katawazai, Asmatullah

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