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2025 European guideline on the management of Chlamydia trachomatis infections
Northern and Western Health & Social Care Trusts, Londonderry, UK.
Department of Health Promotion, Care and Public Health Research Institute (CAPHRI), Maastricht University, Maastricht, the Netherlands; Department of Sexual Health, Infectious Diseases and Environmental Health, Living Lab. Public Health Mosa, South Limburg Public Health Service, Heerlen, the Netherlands.
Department of Sexual Health, Infectious Diseases and Environmental Health, Living Lab. Public Health Mosa, South Limburg Public Health Service, Heerlen, the Netherlands; Department of Social Medicine, Care and Public Health Research Institute (CAPHRI), Maastricht University, Maastricht, the Netherlands; Department of Medical Microbiology, Infectious Diseases and Infection Prevention, Dutch National Chlamydia trachomatis Reference Laboratory, Care and Public Health Research Institute (CAPHRI), Maastricht University Medical Centre (MUMC+), Maastricht, the Netherlands.
Institute of Tropical Medicine, Antwerp, Belgium.
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2025 (English)In: International Journal of STD and AIDS (London), ISSN 0956-4624, E-ISSN 1758-1052, Vol. 36, no 6, p. 434-449Article in journal (Refereed) Published
Abstract [en]

Sexually transmitted Chlamydia trachomatis infections remain common globally and most frequently are asymptomatic. The 2025 European C. trachomatis guideline provides up-to-date guidance regarding indications for testing and treatment of C. trachomatis infections. It includes advice on urogenital and extragenital C. trachomatis testing including the use of self-collected specimens; recommendation to use only validated NAATs for diagnosis; and recommendation to treat all C. trachomatis infections with doxycycline as first line in preference to single-dose azithromycin regimens. The absence of evidence and limited value of broad screening in asymptomatic populations for C. trachomatis infections is also discussed.
Place, publisher, year, edition, pages
Royal Society of Medicine Press, 2025. Vol. 36, no 6, p. 434-449
Keywords [en]
Chlamydia trachomatis, Europe, antibiotic, diagnosis, treatment
National Category
Infectious Medicine
Identifiers
URN: urn:nbn:se:oru:diva-119666DOI: 10.1177/09564624251323678ISI: 001436493600001PubMedID: 40037375Scopus ID: 2-s2.0-105000142002OAI: oai:DiVA.org:oru-119666DiVA, id: diva2:1942604
Available from: 2025-03-05 Created: 2025-03-05 Last updated: 2026-01-23Bibliographically approved

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