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Validation of the Scandinavian neurotrauma committee guidelines - A retrospective study in region Örebro county
School of Medical Sciences, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.
Örebro University, School of Medical Sciences. Department of Neurosurgery, Region Örebro County, Örebro University Hospital, Örebro, Sweden.ORCID iD: 0000-0003-3875-5831
Örebro University, School of Medical Sciences. Örebro University Hospital. Department of Neurosurgery.ORCID iD: 0000-0003-0799-2148
Örebro University, School of Medical Sciences. Department of Neurosurgery, Region Örebro County, Örebro University Hospital, Örebro, Sweden.ORCID iD: 0000-0002-2190-9278
2025 (English)In: Brain and Spine, E-ISSN 2772-5294, Vol. 5, article id 104231Article in journal (Refereed) Published
Abstract [en]

Introduction: Traumatic Brain Injury (TBI) is a global health concern and a leading cause of trauma-related death worldwide. Computed tomography (CT) scan is the gold standard for screening for intracranial bleeding following TBI. Most cases of TBI are mild, with negative CT scans. Different instruments and guidelines are employed to better predict which patients need a CT scan and to minimise unnecessary radiation exposure and save resources. One such instrument is the Scandinavian Neurotrauma Committee guidelines.

Research question: To validate and examine adherence to the Scandinavian Neurotrauma Committee guidelines in Region Örebro County.

Material and methods: We executed a retrospective study with review of patient records and data analysis. Descriptive and comparative statistics were used, along with binary logistic regression analysis to account for confounding factors.

Results: A total of 505 cases were reviewed. Sensitivity of the guidelines was measured at 95% with specificity at 29%. The positive and negative predictive values were 0.77 and 0.69, respectively. A total of 17 false negative cases were found. One case required surgery, during which a chronic subdural hematoma was identified. Adherence to guidelines was 56%, with the lack of analysis of S100B primarily accounting for non-adherence. A total of 54 CT scans were performed outside of guideline indications.

Discussion and conclusions: The guidelines can effectively predict which patients need a CT scan. Increased adherence could potentially decrease the number of CT scans, while inclusion of older age limit as an independent rule-in law for CT scans would increase patient safety.

Place, publisher, year, edition, pages
Elsevier, 2025. Vol. 5, article id 104231
Keywords [en]
Adults, CT, Clinical guidelines, Traumatic brain injury, Validation
National Category
Neurology
Identifiers
URN: urn:nbn:se:oru:diva-120278DOI: 10.1016/j.bas.2025.104231ISI: 001448446500001PubMedID: 40165992Scopus ID: 2-s2.0-86000580439OAI: oai:DiVA.org:oru-120278DiVA, id: diva2:1948217
Funder
Promobilia foundation, A24289The Swedish Brain Foundation, FO2024-00400Swedish Research Council, 2023-02044Available from: 2025-03-28 Created: 2025-03-28 Last updated: 2025-04-02Bibliographically approved

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Trivedi, DhanishaVigren, PatrickBüki, Andras

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